Dabrafenib; preclinical characterization, increased efficacy when combined with trametinib, while BRAF/MEK tool combination reduced skin lesions
King, Alastair J, Arnone, Marc R, Bleam, Maureen R, Moss, Katherine G, Yang, Jingsong, Fedorowicz, Kelly E, Smitheman, Kimberly N, Erhardt, Joseph A, Hughes-Earle, Angela, Kane-Carson, Laurie S, Sinnamon, Robert H, Qi, Hongwei, Rheault, Tara R, Uehling, David E, Laquerre, Sylvie G
Published in PloS one (03.07.2013)
Published in PloS one (03.07.2013)
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Journal Article
Caspase 3 Activation Is Essential for Neuroprotection in Preconditioning
McLaughlin, BethAnn, Hartnett, Karen A., Erhardt, Joseph A., Legos, Jeffrey J., White, Ray F., Barone, Frank C., Aizenman, Elias
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (21.01.2003)
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Journal Article
p38 Activation Is Required Upstream of Potassium Current Enhancement and Caspase Cleavage in Thiol Oxidant-Induced Neuronal Apoptosis
McLaughlin, BethAnn, Pal, Sumon, Tran, Minhnga P, Parsons, Andrew A, Barone, Frank C, Erhardt, Joseph A, Aizenman, Elias
Published in The Journal of neuroscience (15.05.2001)
Published in The Journal of neuroscience (15.05.2001)
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Journal Article
Up-Regulation of Secretory Leukocyte Protease Inhibitor (SLPI) in the Brain after Ischemic Stroke: Adenoviral Expression of SLPI Protects Brain from Ischemic Injury
Wang, Xinkang, Li, Xiang, Xu, Lin, Zhan, Yutian, Yaish-Ohad, Shoshanit, Erhardt, Joseph A, Barone, Frank C, Feuerstein, Giora Z
Published in Molecular pharmacology (01.10.2003)
Published in Molecular pharmacology (01.10.2003)
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Journal Article
Benzofuran-substituted urea derivatives as novel P2Y1 receptor antagonists
Thalji, Reema K., Aiyar, Nambi, Davenport, Elizabeth A., Erhardt, Joseph A., Kallal, Lorena A., Morrow, Dwight M., Senadhi, Shobha, Burns-Kurtis, Cynthia L., Marino, Joseph P.
Published in Bioorganic & medicinal chemistry letters (01.07.2010)
Published in Bioorganic & medicinal chemistry letters (01.07.2010)
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Journal Article
Comparative analyses of the small molecule thrombopoietin receptor agonist eltrombopag and thrombopoietin on in vitro platelet function
Erhardt, Joseph A, Erickson-Miller, Connie L, Aivado, Manuel, Abboud, Melanie, Pillarisetti, Kodandaram, Toomey, John R
Published in Experimental hematology (01.09.2009)
Published in Experimental hematology (01.09.2009)
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Journal Article
Quantitative changes in interleukin proteins following focal stroke in the rat
Legos, Jeffrey J, Whitmore, Robert G, Erhardt, Joseph A, Parsons, Andrew A, Tuma, Ronald F, Barone, Frank C
Published in Neuroscience letters (24.03.2000)
Published in Neuroscience letters (24.03.2000)
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Journal Article
Expression of PEP-19 inhibits apoptosis in PC12 cells
Erhardt, J A, Legos, J J, Johanson, R A, Slemmon, J R, Wang, X
Published in Neuroreport (27.11.2000)
Published in Neuroreport (27.11.2000)
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Journal Article
Benzofuran-substituted urea derivatives as novel P2Y(1) receptor antagonists
Thalji, Reema K, Aiyar, Nambi, Davenport, Elizabeth A, Erhardt, Joseph A, Kallal, Lorena A, Morrow, Dwight M, Senadhi, Shobha, Burns-Kurtis, Cynthia L, Marino, Jr, Joseph P
Published in Bioorganic & medicinal chemistry letters (15.07.2010)
Published in Bioorganic & medicinal chemistry letters (15.07.2010)
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Journal Article
The Novel β-Blocker, Carvedilol, Provides Neuroprotection in Transient Focal Stroke
Savitz, Sean I., Erhardt, Joseph A., Anthony, James V., Gupta, Gaurav, Li, Xiang, Barone, Frank C., Rosenbaum, Daniel M.
Published in Journal of cerebral blood flow and metabolism (01.08.2000)
Published in Journal of cerebral blood flow and metabolism (01.08.2000)
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Journal Article
SB 239063, a novel p38 inhibitor, attenuates early neuronal injury following ischemia
Legos, Jeffrey J., Erhardt, Joseph A., White, Raymond F., Lenhard, Stephen C., Chandra, Sudeep, Parsons, Andrew A., Tuma, Ronald F., Barone, Frank C.
Published in Brain research (16.02.2001)
Published in Brain research (16.02.2001)
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Journal Article
The selective p38 inhibitor SB-239063 protects primary neurons from mild to moderate excitotoxic injury
Legos, Jeffrey J, McLaughlin, BethAnn, Skaper, Stephen D, Strijbos, Paul J.L.M, Parsons, Andrew A, Aizenman, Elias, Herin, Greta A, Barone, Frank C, Erhardt, Joseph A
Published in European journal of pharmacology (28.06.2002)
Published in European journal of pharmacology (28.06.2002)
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Journal Article
A Novel F Box Protein, NFB42, Is Highly Enriched in Neurons and Induces Growth Arrest
Erhardt, J A, Hynicka, W, DiBenedetto, A, Shen, N, Stone, N, Paulson, H, Pittman, R N
Published in The Journal of biological chemistry (25.12.1998)
Published in The Journal of biological chemistry (25.12.1998)
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Journal Article
Selective inhibitors of apoptotic caspases: implications for novel therapeutic strategies
Nuttall, Mark E., Lee, Dennis, McLaughlin, BethAnn, Erhardt, Joseph A.
Published in Drug Discovery Today (01.01.2001)
Published in Drug Discovery Today (01.01.2001)
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Book Review
Journal Article
Activation of Caspase-3/Caspase-3-Like Activity in Rat Cardiomyocytes by an RGD Peptide, but not the GPIIb/IIIa Antagonist Lotrafiban
Erhardt, Joseph A., Ohlstein, Eliot H., Toomey, John R., Gabriel, Melanie A., Willette, Robert N., Yue, Tian-Li, Barone, Frank C., Parsons, Andrew A.
Published in Thrombosis research (15.07.2001)
Published in Thrombosis research (15.07.2001)
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Journal Article
Conference Proceeding
Benzofuran-substituted urea derivatives as novel P2Y sub(1) receptor antagonists
Thalji, Reema K, Aiyar, Nambi, Davenport, Elizabeth A, Erhardt, Joseph A, Kallal, Lorena A, Morrow, Dwight M, Senadhi, Shobha, Burns-Kurtis, Cynthia L
Published in Bioorganic & medicinal chemistry letters (15.07.2010)
Published in Bioorganic & medicinal chemistry letters (15.07.2010)
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Journal Article
P2X1 stimulation promotes thrombin receptor‐mediated platelet aggregation
ERHARDT, J. A., TOOMEY, J. R., DOUGLAS, S. A., JOHNS, D. G.
Published in Journal of thrombosis and haemostasis (01.04.2006)
Published in Journal of thrombosis and haemostasis (01.04.2006)
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