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A Distinctive DNA Damage Response in Human Hematopoietic Stem Cells Reveals an Apoptosis-Independent Role for p53 in Self-Renewal
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Barriers to horizontal cell transformation by extracellular vesicles containing oncogenic H-ras
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Mutant H3 histones drive human pre-leukemic hematopoietic stem cell expansion and promote leukemic aggressiveness
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Published in Nature communications (28.06.2019)
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Reduced Lymphoid Lineage Priming Promotes Human Hematopoietic Stem Cell Expansion
van Galen, Peter, Kreso, Antonija, Wienholds, Erno, Laurenti, Elisa, Eppert, Kolja, Lechman, Eric R., Mbong, Nathan, Hermans, Karin, Dobson, Stephanie, April, Craig, Fan, Jian-Bing, Dick, John E.
Published in Cell stem cell (02.01.2014)
Published in Cell stem cell (02.01.2014)
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Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation
Da Costa, Elodie M, Armaos, Gregory, McInnes, Gabrielle, Beaudry, Annie, Moquin-Beaudry, Gaël, Bertrand-Lehouillier, Virginie, Caron, Maxime, Richer, Chantal, St-Onge, Pascal, Johnson, Jeffrey R, Krogan, Nevan, Sai, Yuka, Downey, Michael, Rafei, Moutih, Boileau, Meaghan, Eppert, Kolja, Flores-Díaz, Ema, Haman, André, Hoang, Trang, Sinnett, Daniel, Beauséjour, Christian, McGraw, Serge, Raynal, Noël J-M
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CD200 expression marks leukemia stem cells in human AML
Ho, Jenny M., Dobson, Stephanie M., Voisin, Veronique, McLeod, Jessica, Kennedy, James A., Mitchell, Amanda, Jin, Liqing, Eppert, Kolja, Bader, Gary, Minden, Mark D., Dick, John E., Wang, Jean C.Y.
Published in Blood advances (10.11.2020)
Published in Blood advances (10.11.2020)
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von Willebrand factor expression in osteosarcoma metastasis
Eppert, Kolja, Wunder, Jay S, Aneliunas, Vicky, Kandel, Rita, Andrulis, Irene L
Published in Modern pathology (01.03.2005)
Published in Modern pathology (01.03.2005)
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Co-amplification and overexpression of CDK4, SAS and MDM2 occurs frequently in human parosteal osteosarcomas
WUNDER, J. S, EPPERT, K, BURROW, S. R, GOGKOZ, N, BELL, R. S, ANDRULIS, I. L
Published in Oncogene (21.01.1999)
Published in Oncogene (21.01.1999)
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The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress
van Galen, Peter, Kreso, Antonija, Mbong, Nathan, Kent, David G., Fitzmaurice, Timothy, Chambers, Joseph E., Xie, Stephanie, Laurenti, Elisa, Hermans, Karin, Eppert, Kolja, Marciniak, Stefan J., Goodall, Jane C., Green, Anthony R., Wouters, Bradly G., Wienholds, Erno, Dick, John E.
Published in Nature (London) (12.06.2014)
Published in Nature (London) (12.06.2014)
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High-Throughput Chemical Screen on Acute Myeloid Leukemia Stem Cells Identifies Novel Anti-LSC Compounds
Iasenza, Isabella Angela, Safa, Safia, Barabe, Frederic, Cellot, Sonia, Wilhelm, Brian T., Eppert, Kolja
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Stem cell gene expression programs influence clinical outcome in human leukemia
Eppert, Kolja, Takenaka, Katsuto, Lechman, Eric R, Waldron, Levi, Nilsson, Björn, van Galen, Peter, Metzeler, Klaus H, Poeppl, Armando, Ling, Vicki, Beyene, Joseph, Canty, Angelo J, Danska, Jayne S, Bohlander, Stefan K, Buske, Christian, Minden, Mark D, Golub, Todd R, Jurisica, Igor, Ebert, Benjamin L, Dick, John E
Published in Nature medicine (01.09.2011)
Published in Nature medicine (01.09.2011)
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GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo
Pabst, Caroline, Bergeron, Anne, Lavallée, Vincent-Philippe, Yeh, Jonathan, Gendron, Patrick, Norddahl, Gudmundur L., Krosl, Jana, Boivin, Isabel, Deneault, Eric, Simard, Jessica, Imren, Suzan, Boucher, Geneviève, Eppert, Kolja, Herold, Tobias, Bohlander, Stefan K., Humphries, Keith, Lemieux, Sébastien, Hébert, Josée, Sauvageau, Guy, Barabé, Frédéric
Published in Blood (21.04.2016)
Published in Blood (21.04.2016)
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The Role of Histone H3-K27M Mutation in Preleukemic HSC Expansion
Dakik, Hassan, Boileau, Meaghan, Worme, Samantha, Jessa, Selin, Iasenza, Isabella, Neumann, Andrea, Sun, Yi Ling, Saby, Manon, Craig, Morgan, Kleinman, Claudia L, Eppert, Kolja
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Mechanisms and Antitumor Activity of a Binary EGFR/DNA-Targeting Strategy Overcomes Resistance of Glioblastoma Stem Cells to Temozolomide
Sharifi, Zeinab, Abdulkarim, Bassam, Meehan, Brian, Rak, Janusz, Daniel, Paul, Schmitt, Julie, Lauzon, Nidia, Eppert, Kolja, Duncan, Heather M, Petrecca, Kevin, Guiot, Marie-Christine, Jean-Claude, Bertrand, Sabri, Siham
Published in Clinical cancer research (15.12.2019)
Published in Clinical cancer research (15.12.2019)
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The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
Zhang, Jinghui, Ding, Li, Holmfeldt, Linda, Wu, Gang, Heatley, Sue L., Payne-Turner, Debbie, Easton, John, Chen, Xiang, Wang, Jianmin, Rusch, Michael, Lu, Charles, Chen, Shann-Ching, Wei, Lei, Collins-Underwood, J. Racquel, Ma, Jing, Roberts, Kathryn G., Pounds, Stanley B., Ulyanov, Anatoly, Becksfort, Jared, Gupta, Pankaj, Huether, Robert, Kriwacki, Richard W., Parker, Matthew, McGoldrick, Daniel J., Zhao, David, Alford, Daniel, Espy, Stephen, Bobba, Kiran Chand, Song, Guangchun, Pei, Deqing, Cheng, Cheng, Roberts, Stefan, Barbato, Michael I., Campana, Dario, Coustan-Smith, Elaine, Shurtleff, Sheila A., Raimondi, Susana C., Kleppe, Maria, Cools, Jan, Shimano, Kristin A., Hermiston, Michelle L., Doulatov, Sergei, Eppert, Kolja, Laurenti, Elisa, Notta, Faiyaz, Dick, John E., Basso, Giuseppe, Hunger, Stephen P., Loh, Mignon L., Devidas, Meenakshi, Wood, Brent, Winter, Stuart, Dunsmore, Kimberley P., Fulton, Robert S., Fulton, Lucinda L., Hong, Xin, Harris, Christopher C., Dooling, David J., Ochoa, Kerri, Johnson, Kimberly J., Obenauer, John C., Evans, William E., Pui, Ching-Hon, Naeve, Clayton W., Ley, Timothy J., Mardis, Elaine R., Wilson, Richard K., Downing, James R., Mullighan, Charles G.
Published in Nature (London) (12.01.2012)
Published in Nature (London) (12.01.2012)
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