Antisense STAT3 inhibitor decreases viability of myelodysplastic and leukemic stem cells
Shastri, Aditi, Choudhary, Gaurav, Teixeira, Margarida, Gordon-Mitchell, Shanisha, Ramachandra, Nandini, Bernard, Lumie, Bhattacharyya, Sanchari, Lopez, Robert, Pradhan, Kith, Giricz, Orsolya, Ravipati, Goutham, Wong, Li-Fan, Cole, Sally, Bhagat, Tushar D, Feld, Jonathan, Dhar, Yosman, Bartenstein, Matthias, Thiruthuvanathan, Victor J, Wickrema, Amittha, Ye, B Hilda, Frank, David A, Pellagatti, Andrea, Boultwood, Jacqueline, Zhou, Tianyuan, Kim, Youngsoo, MacLeod, A Robert, Epling-Burnette, P K, Ye, Minwei, McCoon, Patricia, Woessner, Richard, Steidl, Ulrich, Will, Britta, Verma, Amit
Published in The Journal of clinical investigation (01.12.2018)
Published in The Journal of clinical investigation (01.12.2018)
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Clonal expansion of T NK-cells during tyrosine kinase inhibitor dasatinib therapy
Mustjoki, S, Ekblom, M, Arstila, T P, Dybedal, I, Epling-Burnette, P K, Guilhot, F, Hjorth-Hansen, H, Höglund, M, Kovanen, P, Laurinolli, T, Liesveld, J, Paquette, R, Pinilla-Ibarz, J, Rauhala, A, Shah, N, Simonsson, B, Sinisalo, M, Steegmann, J L, Stenke, L, Porkka, K
Published in Leukemia (01.08.2009)
Published in Leukemia (01.08.2009)
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Autoimmune diseases and myelodysplastic syndromes
Komrokji, Rami S., Kulasekararaj, Austin, Al Ali, Najla H., Kordasti, Shahram, Bart‐Smith, Emily, Craig, Benjamin M., Padron, Eric, Zhang, Ling, Lancet, Jeffrey E., Pinilla‐Ibarz, Javier, List, Alan F., Mufti, Ghulam J., Epling‐Burnette, Pearlie K.
Published in American journal of hematology (01.05.2016)
Published in American journal of hematology (01.05.2016)
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Journal Article
Role of Polyamines in Immune Cell Functions
Hesterberg, Rebecca S, Cleveland, John L, Epling-Burnette, Pearlie K
Published in Medical Sciences (08.03.2018)
Published in Medical Sciences (08.03.2018)
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Journal Article
Book Review
SHP2 inhibition displays efficacy as a monotherapy and in combination with JAK2 inhibition in preclinical models of myeloproliferative neoplasms
Pandey, Garima, Mazzacurati, Lucia, Rowsell, Tegan M., Horvat, Nathan P., Amin, Narmin E., Zhang, Guolin, Akuffo, Afua A., Colin‐Leitzinger, Christelle M., Haura, Eric B., Kuykendall, Andrew T., Zhang, Ling, Epling‐Burnette, Pearlie K., Reuther, Gary W.
Published in American journal of hematology (01.06.2024)
Published in American journal of hematology (01.06.2024)
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inflammatory microenvironment in MDS
Yang, Lili, Qian, Yaqin, Eksioglu, Erika, Epling-Burnette, Pearlie K, Wei, Sheng
Published in Cellular and molecular life sciences : CMLS (01.05.2015)
Published in Cellular and molecular life sciences : CMLS (01.05.2015)
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Journal Article
CD16xCD33 bispecific killer cell engager (BiKE) activates NK cells against primary MDS and MDSC CD33+ targets
Gleason, Michelle K., Ross, Julie A., Warlick, Erica D., Lund, Troy C., Verneris, Michael R., Wiernik, Andres, Spellman, Stephen, Haagenson, Michael D., Lenvik, Alexander J., Litzow, Mark R., Epling-Burnette, Pearlie K., Blazar, Bruce R., Weiner, Louis M., Weisdorf, Daniel J., Vallera, Daniel A., Miller, Jeffrey S.
Published in Blood (08.05.2014)
Published in Blood (08.05.2014)
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Journal Article
critical role for phosphatase haplodeficiency in the selective suppression of deletion 5q MDS by lenalidomide
Wei, Sheng, Chen, Xianghong, Rocha, Kathy, Epling-Burnette, P.K, Djeu, Julie Y, Liu, Qing, Byrd, John, Sokol, Lubomir, Lawrence, Nick, Pireddu, Roberta, Dewald, Gordon, Williams, Ann, Maciejewski, Jaroslaw, List, Alan
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (04.08.2009)
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Journal Article
Icariin and its derivative, ICT, exert anti-inflammatory, anti-tumor effects, and modulate myeloid derived suppressive cells (MDSCs) functions
Zhou, Junmin, Wu, Jinfeng, Chen, Xianghong, Fortenbery, Nicole, Eksioglu, Erika, Kodumudi, Krithika N., PK, Epling-Burnette, Dong, Jingcheng, Djeu, Julie Y., Wei, Sheng
Published in International immunopharmacology (01.07.2011)
Published in International immunopharmacology (01.07.2011)
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Journal Article
Lenalidomide promotes p53 degradation by inhibiting MDM2 auto-ubiquitination in myelodysplastic syndrome with chromosome 5q deletion
Wei, S, Chen, X, McGraw, K, Zhang, L, Komrokji, R, Clark, J, Caceres, G, Billingsley, D, Sokol, L, Lancet, J, Fortenbery, N, Zhou, J, Eksioglu, E A, Sallman, D, Wang, H, Epling-Burnette, P K, Djeu, J, Sekeres, M, Maciejewski, J P, List, A
Published in Oncogene (28.02.2013)
Published in Oncogene (28.02.2013)
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Journal Article
Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation
Park, Derek S, Akuffo, Afua A, Muench, David E, Grimes, H Leighton, Epling-Burnette, Pearlie K, Maini, Philip K, Anderson, Alexander R A, Bonsall, Michael B
Published in PLoS computational biology (01.04.2019)
Published in PLoS computational biology (01.04.2019)
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Journal Article
Cross‐sectional associations between cutaneous viral infections and regulatory T lymphocytes in circulation
Hampras, S.S., Tommasino, M., Zhao, Y., Messina, J.L., Giuliano, A.R., Fenske, N.A., Cherpelis, B., Hesterberg, R.S., Akuffo, A.A., Amorrortu, R.P., Balliu, J., Vijayan, L., Gheit, T., Epling‐Burnette, P.K., Rollison, D.E.
Published in British journal of dermatology (1951) (01.06.2019)
Published in British journal of dermatology (1951) (01.06.2019)
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Journal Article
Induction of myelodysplasia by myeloid-derived suppressor cells
Chen, Xianghong, Eksioglu, Erika A, Zhou, Junmin, Zhang, Ling, Djeu, Julie, Fortenbery, Nicole, Epling-Burnette, Pearlie, Van Bijnen, Sandra, Dolstra, Harry, Cannon, John, Youn, Je-in, Donatelli, Sarah S, Qin, Dahui, De Witte, Theo, Tao, Jianguo, Wang, Huaquan, Cheng, Pingyan, Gabrilovich, Dmitry I, List, Alan, Wei, Sheng
Published in The Journal of clinical investigation (01.11.2013)
Published in The Journal of clinical investigation (01.11.2013)
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Journal Article
Expansion of effector memory regulatory T cells represents a novel prognostic factor in lower risk myelodysplastic syndrome
Mailloux, Adam W, Sugimori, Chiharu, Komrokji, Rami S, Yang, Lili, Maciejewski, Jaroslaw P, Sekeres, Mikkael A, Paquette, Ronald, Loughran, Jr, Thomas P, List, Alan F, Epling-Burnette, Pearlie K
Published in The Journal of immunology (1950) (15.09.2012)
Published in The Journal of immunology (1950) (15.09.2012)
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Journal Article
Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression
Epling-Burnette, P K, Liu, J H, Catlett-Falcone, R, Turkson, J, Oshiro, M, Kothapalli, R, Li, Y, Wang, J M, Yang-Yen, H F, Karras, J, Jove, R, Loughran, Jr, T P
Published in The Journal of clinical investigation (01.02.2001)
Published in The Journal of clinical investigation (01.02.2001)
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Journal Article
GM-CSF–dependent pSTAT5 sensitivity is a feature with therapeutic potential in chronic myelomonocytic leukemia
Padron, Eric, Painter, Jeffrey S., Kunigal, Sateesh, Mailloux, Adam W., McGraw, Kathy, McDaniel, Jessica M., Kim, Eunhee, Bebbington, Christopher, Baer, Mark, Yarranton, Geoffrey, Lancet, Jeffrey, Komrokji, Rami S., Abdel-Wahab, Omar, List, Alan F., Epling-Burnette, Pearlie K.
Published in Blood (20.06.2013)
Published in Blood (20.06.2013)
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Journal Article
Metabolic Vulnerabilities and Epigenetic Dysregulation in Myeloproliferative Neoplasms
Sharma, Vasundhara, Wright, Kenneth L, Epling-Burnette, Pearlie K, Reuther, Gary W
Published in Frontiers in immunology (30.11.2020)
Published in Frontiers in immunology (30.11.2020)
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Journal Article
Ligand-mediated protein degradation reveals functional conservation among sequence variants of the CUL4-type E3 ligase substrate receptor cereblon
Akuffo, Afua A., Alontaga, Aileen Y., Metcalf, Rainer, Beatty, Matthew S., Becker, Andreas, McDaniel, Jessica M., Hesterberg, Rebecca S., Goodheart, William E., Gunawan, Steven, Ayaz, Muhammad, Yang, Yan, Karim, Md Rezaul, Orobello, Morgan E., Daniel, Kenyon, Guida, Wayne, Yoder, Jeffrey A., Rajadhyaksha, Anjali M., Schönbrunn, Ernst, Lawrence, Harshani R., Lawrence, Nicholas J., Epling-Burnette, Pearlie K.
Published in The Journal of biological chemistry (20.04.2018)
Published in The Journal of biological chemistry (20.04.2018)
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Journal Article
Efficacy of ALK5 inhibition in myelofibrosis
Yue, Lanzhu, Bartenstein, Matthias, Zhao, Wanke, Ho, Wanting Tina, Han, Ying, Murdun, Cem, Mailloux, Adam W, Zhang, Ling, Wang, Xuefeng, Budhathoki, Anjali, Pradhan, Kith, Rapaport, Franck, Wang, Huaquan, Shao, Zonghong, Ren, Xiubao, Steidl, Ulrich, Levine, Ross L, Zhao, Zhizhuang Joe, Verma, Amit, Epling-Burnette, Pearlie K
Published in JCI insight (06.04.2017)
Published in JCI insight (06.04.2017)
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