Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA
Schwartz, Schraga, Bernstein, Douglas A., Mumbach, Maxwell R., Jovanovic, Marko, Herbst, Rebecca H., León-Ricardo, Brian X., Engreitz, Jesse M., Guttman, Mitchell, Satija, Rahul, Lander, Eric S., Fink, Gerald, Regev, Aviv
Published in Cell (25.09.2014)
Published in Cell (25.09.2014)
Get full text
Journal Article
RNA-RNA Interactions Enable Specific Targeting of Noncoding RNAs to Nascent Pre-mRNAs and Chromatin Sites
Engreitz, Jesse M., Sirokman, Klara, McDonel, Patrick, Shishkin, Alexander A., Surka, Christine, Russell, Pamela, Grossman, Sharon R., Chow, Amy Y., Guttman, Mitchell, Lander, Eric S.
Published in Cell (25.09.2014)
Published in Cell (25.09.2014)
Get full text
Journal Article
Local regulation of gene expression by lncRNA promoters, transcription and splicing
Engreitz, Jesse M., Haines, Jenna E., Perez, Elizabeth M., Munson, Glen, Chen, Jenny, Kane, Michael, McDonel, Patrick E., Guttman, Mitchell, Lander, Eric S.
Published in Nature (London) (17.11.2016)
Published in Nature (London) (17.11.2016)
Get full text
Journal Article
The Lin28/let-7 Axis Regulates Glucose Metabolism
Zhu, Hao, Shyh-Chang, Ng, Segrè, Ayellet V., Shinoda, Gen, Shah, Samar P., Einhorn, William S., Takeuchi, Ayumu, Engreitz, Jesse M., Hagan, John P., Kharas, Michael G., Urbach, Achia, Thornton, James E., Triboulet, Robinson, Gregory, Richard I., Altshuler, David, Daley, George Q.
Published in Cell (30.09.2011)
Published in Cell (30.09.2011)
Get full text
Journal Article
Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations
Fulco, Charles P., Nasser, Joseph, Jones, Thouis R., Munson, Glen, Bergman, Drew T., Subramanian, Vidya, Grossman, Sharon R., Anyoha, Rockwell, Doughty, Benjamin R., Patwardhan, Tejal A., Nguyen, Tung H., Kane, Michael, Perez, Elizabeth M., Durand, Neva C., Lareau, Caleb A., Stamenova, Elena K., Aiden, Erez Lieberman, Lander, Eric S., Engreitz, Jesse M.
Published in Nature genetics (01.12.2019)
Published in Nature genetics (01.12.2019)
Get full text
Journal Article
The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome
Engreitz, Jesse M, Pandya-Jones, Amy, McDonel, Patrick, Shishkin, Alexander, Sirokman, Klara, Surka, Christine, Kadri, Sabah, Xing, Jeffrey, Goren, Alon, Lander, Eric S, Plath, Kathrin, Guttman, Mitchell
Published in Science (American Association for the Advancement of Science) (16.08.2013)
Published in Science (American Association for the Advancement of Science) (16.08.2013)
Get full text
Journal Article
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability
Munschauer, Mathias, Nguyen, Celina T., Sirokman, Klara, Hartigan, Christina R., Hogstrom, Larson, Engreitz, Jesse M., Ulirsch, Jacob C., Fulco, Charles P., Subramanian, Vidya, Chen, Jenny, Schenone, Monica, Guttman, Mitchell, Carr, Steven A., Lander, Eric S.
Published in Nature (London) (01.09.2018)
Published in Nature (London) (01.09.2018)
Get full text
Journal Article
Systematic mapping of functional enhancer-promoter connections with CRISPR interference
Fulco, Charles P., Munschauer, Mathias, Anyoha, Rockwell, Munson, Glen, Grossman, Sharon R., Perez, Elizabeth M., Kane, Michael, Cleary, Brian, Lander, Eric S., Engreitz, Jesse M.
Published in Science (American Association for the Advancement of Science) (11.11.2016)
Published in Science (American Association for the Advancement of Science) (11.11.2016)
Get full text
Journal Article
Cohesin Loss Eliminates All Loop Domains
Rao, Suhas S.P., Huang, Su-Chen, Glenn St Hilaire, Brian, Engreitz, Jesse M., Perez, Elizabeth M., Kieffer-Kwon, Kyong-Rim, Sanborn, Adrian L., Johnstone, Sarah E., Bascom, Gavin D., Bochkov, Ivan D., Huang, Xingfan, Shamim, Muhammad S., Shin, Jaeweon, Turner, Douglass, Ye, Ziyi, Omer, Arina D., Robinson, James T., Schlick, Tamar, Bernstein, Bradley E., Casellas, Rafael, Lander, Eric S., Aiden, Erez Lieberman
Published in Cell (05.10.2017)
Published in Cell (05.10.2017)
Get full text
Journal Article
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease
Ameen, Mohamed, Sundaram, Laksshman, Shen, Mengcheng, Banerjee, Abhimanyu, Kundu, Soumya, Nair, Surag, Shcherbina, Anna, Gu, Mingxia, Wilson, Kitchener D., Varadarajan, Avyay, Vadgama, Nirmal, Balsubramani, Akshay, Wu, Joseph C., Engreitz, Jesse M., Farh, Kyle, Karakikes, Ioannis, Wang, Kevin C., Quertermous, Thomas, Greenleaf, William J., Kundaje, Anshul
Published in Cell (22.12.2022)
Published in Cell (22.12.2022)
Get full text
Journal Article
Recurrent and functional regulatory mutations in breast cancer
Rheinbay, Esther, Parasuraman, Prasanna, Grimsby, Jonna, Tiao, Grace, Engreitz, Jesse M., Kim, Jaegil, Lawrence, Michael S., Taylor-Weiner, Amaro, Rodriguez-Cuevas, Sergio, Rosenberg, Mara, Hess, Julian, Stewart, Chip, Maruvka, Yosef E., Stojanov, Petar, Cortes, Maria L., Seepo, Sara, Cibulskis, Carrie, Tracy, Adam, Pugh, Trevor J., Lee, Jesse, Zheng, Zongli, Ellisen, Leif W., Iafrate, A. John, Boehm, Jesse S., Gabriel, Stacey B., Meyerson, Matthew, Golub, Todd R., Baselga, Jose, Hidalgo-Miranda, Alfredo, Shioda, Toshi, Bernards, Andre, Lander, Eric S., Getz, Gad
Published in Nature (London) (06.07.2017)
Published in Nature (London) (06.07.2017)
Get full text
Journal Article
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood
Joung, Julia, Engreitz, Jesse M., Konermann, Silvana, Abudayyeh, Omar O., Verdine, Vanessa K., Aguet, Francois, Gootenberg, Jonathan S., Sanjana, Neville E., Wright, Jason B., Fulco, Charles P., Tseng, Yuen-Yi, Yoon, Charles H., Boehm, Jesse S., Lander, Eric S., Zhang, Feng
Published in Nature (London) (17.08.2017)
Published in Nature (London) (17.08.2017)
Get full text
Journal Article
Compatibility rules of human enhancer and promoter sequences
Bergman, Drew T., Jones, Thouis R., Liu, Vincent, Ray, Judhajeet, Jagoda, Evelyn, Siraj, Layla, Kang, Helen Y., Nasser, Joseph, Kane, Michael, Rios, Antonio, Nguyen, Tung H., Grossman, Sharon R., Fulco, Charles P., Lander, Eric S., Engreitz, Jesse M.
Published in Nature (London) (07.07.2022)
Published in Nature (London) (07.07.2022)
Get full text
Journal Article
Combining SNP-to-gene linking strategies to identify disease genes and assess disease omnigenicity
Gazal, Steven, Weissbrod, Omer, Hormozdiari, Farhad, Dey, Kushal K., Nasser, Joseph, Jagadeesh, Karthik A., Weiner, Daniel J., Shi, Huwenbo, Fulco, Charles P., O’Connor, Luke J., Pasaniuc, Bogdan, Engreitz, Jesse M., Price, Alkes L.
Published in Nature genetics (01.06.2022)
Published in Nature genetics (01.06.2022)
Get full text
Journal Article
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
Moynihan, Kelly D, Opel, Cary F, Szeto, Gregory L, Tzeng, Alice, Zhu, Eric F, Engreitz, Jesse M, Williams, Robert T, Rakhra, Kavya, Zhang, Michael H, Rothschilds, Adrienne M, Kumari, Sudha, Kelly, Ryan L, Kwan, Byron H, Abraham, Wuhbet, Hu, Kevin, Mehta, Naveen K, Kauke, Monique J, Suh, Heikyung, Cochran, Jennifer R, Lauffenburger, Douglas A, Wittrup, K Dane, Irvine, Darrell J
Published in Nature medicine (01.12.2016)
Published in Nature medicine (01.12.2016)
Get full text
Journal Article
A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression
Gupta, Rajat M., Hadaya, Joseph, Trehan, Aditi, Zekavat, Seyedeh M., Roselli, Carolina, Klarin, Derek, Emdin, Connor A., Hilvering, Catharina R.E., Bianchi, Valerio, Mueller, Christian, Khera, Amit V., Ryan, Russell J.H., Engreitz, Jesse M., Issner, Robbyn, Shoresh, Noam, Epstein, Charles B., de Laat, Wouter, Brown, Jonathan D., Schnabel, Renate B., Bernstein, Bradley E., Kathiresan, Sekar
Published in Cell (27.07.2017)
Published in Cell (27.07.2017)
Get full text
Journal Article
Identifying disease-critical cell types and cellular processes by integrating single-cell RNA-sequencing and human genetics
Jagadeesh, Karthik A., Dey, Kushal K., Montoro, Daniel T., Mohan, Rahul, Gazal, Steven, Engreitz, Jesse M., Xavier, Ramnik J., Price, Alkes L., Regev, Aviv
Published in Nature genetics (01.10.2022)
Published in Nature genetics (01.10.2022)
Get full text
Journal Article
Ribosome Levels Selectively Regulate Translation and Lineage Commitment in Human Hematopoiesis
Khajuria, Rajiv K., Munschauer, Mathias, Ulirsch, Jacob C., Fiorini, Claudia, Ludwig, Leif S., McFarland, Sean K., Abdulhay, Nour J., Specht, Harrison, Keshishian, Hasmik, Mani, D.R., Jovanovic, Marko, Ellis, Steven R., Fulco, Charles P., Engreitz, Jesse M., Schütz, Sabina, Lian, John, Gripp, Karen W., Weinberg, Olga K., Pinkus, Geraldine S., Gehrke, Lee, Regev, Aviv, Lander, Eric S., Gazda, Hanna T., Lee, Winston Y., Panse, Vikram G., Carr, Steven A., Sankaran, Vijay G.
Published in Cell (22.03.2018)
Published in Cell (22.03.2018)
Get full text
Journal Article