CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells
Klatt, Nichole R, Shudo, Emi, Ortiz, Alex M, Engram, Jessica C, Paiardini, Mirko, Lawson, Benton, Miller, Michael D, Else, James, Pandrea, Ivona, Estes, Jacob D, Apetrei, Cristian, Schmitz, Joern E, Ribeiro, Ruy M, Perelson, Alan S, Silvestri, Guido
Published in PLoS pathogens (01.01.2010)
Published in PLoS pathogens (01.01.2010)
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A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo
Riddick, Nadeene E, Hermann, Emilia A, Loftin, Lamorris M, Elliott, Sarah T, Wey, Winston C, Cervasi, Barbara, Taaffe, Jessica, Engram, Jessica C, Li, Bing, Else, James G, Li, Yingying, Hahn, Beatrice H, Derdeyn, Cynthia A, Sodora, Donald L, Apetrei, Cristian, Paiardini, Mirko, Silvestri, Guido, Collman, Ronald G
Published in PLoS pathogens (01.08.2010)
Published in PLoS pathogens (01.08.2010)
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Critical role of CD4 T cells in maintaining lymphoid tissue structure for immune cell homeostasis and reconstitution
Zeng, Ming, Paiardini, Mirko, Engram, Jessica C., Beilman, Greg J., Chipman, Jeffrey G., Schacker, Timothy W., Silvestri, Guido, Haase, Ashley T.
Published in Blood (30.08.2012)
Published in Blood (30.08.2012)
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Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques
Ortiz, Alexandra M, Klatt, Nichole R, Li, Bing, Yi, Yanjie, Tabb, Brian, Hao, Xing Pei, Sternberg, Lawrence, Lawson, Benton, Carnathan, Paul M, Cramer, Elizabeth M, Engram, Jessica C, Little, Dawn M, Ryzhova, Elena, Gonzalez-Scarano, Francisco, Paiardini, Mirko, Ansari, Aftab A, Ratcliffe, Sarah, Else, James G, Brenchley, Jason M, Collman, Ronald G, Estes, Jacob D, Derdeyn, Cynthia A, Silvestri, Guido
Published in The Journal of clinical investigation (01.11.2011)
Published in The Journal of clinical investigation (01.11.2011)
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Severe Depletion of Mucosal CD4+ T Cells in AIDS-Free Simian Immunodeficiency Virus-Infected Sooty Mangabeys
Gordon, Shari N, Klatt, Nichole R, Bosinger, Steven E, Brenchley, Jason M, Milush, Jeffrey M, Engram, Jessica C, Dunham, Richard M, Paiardini, Mirko, Klucking, Sara, Danesh, Ali, Strobert, Elizabeth A, Apetrei, Cristian, Pandrea, Ivona V, Kelvin, David, Douek, Daniel C, Staprans, Silvija I, Sodora, Donald L, Silvestri, Guido
Published in The Journal of immunology (1950) (01.09.2007)
Published in The Journal of immunology (1950) (01.09.2007)
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Viral CTL escape mutants are generated in lymph nodes and subsequently become fixed in plasma and rectal mucosa during acute SIV infection of macaques
Vanderford, Thomas H, Bleckwehl, Chelsea, Engram, Jessica C, Dunham, Richard M, Klatt, Nichole R, Feinberg, Mark B, Garber, David A, Betts, Michael R, Silvestri, Guido
Published in PLoS pathogens (01.05.2011)
Published in PLoS pathogens (01.05.2011)
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Dynamics of Simian Immunodeficiency Virus SIVmac239 Infection in Pigtail Macaques
KLATT, Nlchole R, CANARY, Lauren A, SILVESTRI, Guido, BRENCHLEY, Jason M, VANDERFORD, Thomas H, VINTON, Caroi L, ENGRAM, Jessica C, DUNHAM, Richard M, CRONISE, Heather E, SWERCZEK, Joanna M, LAFONT, Bernard A. P, PICKER, Louis J
Published in Journal of Virology (01.01.2012)
Published in Journal of Virology (01.01.2012)
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Elevated Levels of Innate Immune Modulators in Lymph Nodes and Blood Are Associated with More-Rapid Disease Progression in Simian Immunodeficiency Virus-Infected Monkeys
DURUDAS, Andre, MILUSH, Jeffrey M, CHEN, Hui-Ling, ENGRAM, Jessica C, SILVESTRI, Guido, SODORA, Donald L
Published in Journal of Virology (01.12.2009)
Published in Journal of Virology (01.12.2009)
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Short-Lived Infected Cells Support Virus Replication in Sooty Mangabeys Naturally Infected with Simian Immunodeficiency Virus: Implications for AIDS Pathogenesis
GORDON, Shari N, DUNHAM, Richard M, HA YOUN LEE, HAASE, Ashley T, MILLER, Michael D, KAUR, Amitinder, STAPRANS, Silvija I, PERELSON, Alan S, FEINBERG, Mark B, SILVESTRI, Guido, ENGRAM, Jessica C, ESTES, Jacob, ZICHUN WANG, KLATT, Nichole R, PAIARDINI, Mirko, PANDREA, Ivona V, APETREI, Cristian, SODORA, Donald L
Published in Journal of Virology (01.04.2008)
Published in Journal of Virology (01.04.2008)
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Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys
Klatt, Nichole R, Villinger, Francois, Bostik, Pavel, Gordon, Shari N, Pereira, Lara, Engram, Jessica C, Mayne, Ann, Dunham, Richard M, Lawson, Benton, Ratcliffe, Sarah J, Sodora, Donald L, Else, James, Reimann, Keith, Staprans, Silvija I, Haase, Ashley T, Estes, Jacob D, Silvestri, Guido, Ansari, Aftab A
Published in The Journal of clinical investigation (01.06.2008)
Published in The Journal of clinical investigation (01.06.2008)
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A Five-Year Longitudinal Analysis of Sooty Mangabeys Naturally Infected with Simian Immunodeficiency Virus Reveals a Slow but Progressive Decline in CD4+ T-Cell Count Whose Magnitude Is Not Predicted by Viral Load or Immune Activation
Taaffe, Jessica, Chahroudi, Ann, Engram, Jessica, Sumpter, Beth, Meeker, Tracy, Ratcliffe, Sarah, Paiardini, Mirko, Else, James, Silvestri, Guido
Published in Journal of Virology (01.06.2010)
Published in Journal of Virology (01.06.2010)
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Adenovirus Vector-Induced Immune Responses in Nonhuman Primates: Responses to Prime Boost Regimens
Tatsis, Nia, Lasaro, Marcio O, Lin, Shih-Wen, Xiang, Zhi Q, Zhou, Dongming, DiMenna, Lauren, Li, Hua, Bian, Ang, Abdulla, Sarah, Li, Yan, Giles-Davis, Wynetta, Engram, Jessica, Ratcliffe, Sarah J, Silvestri, Guido, Ertl, Hildegund C, Betts, Michael R
Published in The Journal of immunology (1950) (15.05.2009)
Published in The Journal of immunology (1950) (15.05.2009)
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Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates
Engram, Jessica C., Cervasi, Barbara, Borghans, Jose A.M., Klatt, Nichole R., Gordon, Shari N., Chahroudi, Ann, Else, James G., Mittler, Robert S., Sodora, Donald L., de Boer, Rob J., Brenchley, Jason M., Silvestri, Guido, Paiardini, Mirko
Published in Blood (05.08.2010)
Published in Blood (05.08.2010)
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Vaccine-Induced, Simian Immunodeficiency Virus-Specific CD8+ T Cells Reduce Virus Replication but Do Not Protect from Simian Immunodeficiency Virus Disease Progression
Engram, Jessica C, Dunham, Richard M, Makedonas, George, Vanderford, Thomas H, Sumpter, Beth, Klatt, Nichole R, Ratcliffe, Sarah J, Garg, Seema, Paiardini, Mirko, McQuoid, Monica, Altman, John D, Staprans, Silvija I, Betts, Michael R, Garber, David A, Feinberg, Mark B, Silvestri, Guido
Published in The Journal of immunology (1950) (01.07.2009)
Published in The Journal of immunology (1950) (01.07.2009)
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Is the Gut the Major Source of Virus in Early Simian Immunodeficiency Virus Infection?
LAY, Matthew D. H, PETRAVIC, Janka, GORDON, Shari N, ENGRAM, Jessica, SILVESTRI, Guido, DAVENPORT, Miles P
Published in Journal of Virology (01.08.2009)
Published in Journal of Virology (01.08.2009)
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Bone marrow–based homeostatic proliferation of mature T cells in nonhuman primates: implications for AIDS pathogenesis
Paiardini, Mirko, Cervasi, Barbara, Engram, Jessica C., Gordon, Shari N., Klatt, Nichole R., Muthukumar, Alagarraju, Else, James, Mittler, Robert S., Staprans, Silvija I., Sodora, Donald L., Silvestri, Guido
Published in Blood (15.01.2009)
Published in Blood (15.01.2009)
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Vaccine-induced T cells Provide Partial Protection Against High-dose Rectal SIVmac239 Challenge of Rhesus Macaques
Lasaro, Marcio O, Haut, Larissa H, Zhou, Xiangyang, Xiang, Zhiquan, Zhou, Dongming, Li, Yan, Giles-Davis, Wynetta, Li, Hua, Engram, Jessica C, DiMenna, Lauren J, Bian, Ang, Sazanovich, Marina, Parzych, Elizabeth M, Kurupati, Raj, Small, Juliana C, Wu, Te-Lang, Leskowitz, Rachel M, Klatt, Nicole R, Brenchley, Jason M, Garber, David A, Lewis, Mark, Ratcliffe, Sarah J, Betts, Michael R, Silvestri, Guido, Ertl, Hildegund C
Published in Molecular therapy (01.02.2011)
Published in Molecular therapy (01.02.2011)
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Introduction of mismatches in a random shRNA-encoding library improves potency for phenotypic selection
Wang, Yongping, Speier, Jacqueline S, Engram-Pearl, Jessica, Wilson, Robert B
Published in PloS one (03.02.2014)
Published in PloS one (03.02.2014)
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Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells
Milush, Jeffrey M, Mir, Kiran D, Sundaravaradan, Vasudha, Gordon, Shari N, Engram, Jessica, Cano, Christopher A, Reeves, Jacqueline D, Anton, Elizabeth, O'Neill, Eduardo, Butler, Eboneé, Hancock, Kathy, Cole, Kelly S, Brenchley, Jason M, Else, James G, Silvestri, Guido, Sodora, Donald L
Published in The Journal of clinical investigation (01.03.2011)
Published in The Journal of clinical investigation (01.03.2011)
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Correlates of Preserved CD4+ T Cell Homeostasis during Natural, Nonpathogenic Simian Immunodeficiency Virus Infection of Sooty Mangabeys: Implications for AIDS Pathogenesis
Sumpter, Beth, Dunham, Richard, Gordon, Shari, Engram, Jessica, Hennessy, Margaret, Kinter, Audrey, Paiardini, Mirko, Cervasi, Barbara, Klatt, Nichole, McClure, Harold, Milush, Jeffrey M, Staprans, Silvija, Sodora, Donald L, Silvestri, Guido
Published in The Journal of immunology (1950) (01.02.2007)
Published in The Journal of immunology (1950) (01.02.2007)
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