Efficacy and safety of olorinab, a full agonist of the cannabinoid receptor 2, for the treatment of abdominal pain in patients with irritable bowel syndrome: Results from a phase 2b randomized placebo‐controlled trial (CAPTIVATE)
Chang, Lin, Cash, Brooks D., Lembo, Anthony, Kunkel, David C., English, Brett A., Lindstrom, Beatriz, Gu, Guibao, Skare, Sharon, Gilder, Kye, Turner, Stewart, Cataldi, Fabio, Lipkis, Donald, Tack, Jan
Published in Neurogastroenterology and motility (01.05.2023)
Published in Neurogastroenterology and motility (01.05.2023)
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Disposed to Distraction: Genetic Variation in the Cholinergic System Influences Distractibility But Not Time-on-Task Effects
Berry, Anne S., Demeter, Elise, Sabhapathy, Surya, English, Brett A., Blakely, Randy D., Sarter, Martin, Lustig, Cindy
Published in Journal of cognitive neuroscience (01.09.2014)
Published in Journal of cognitive neuroscience (01.09.2014)
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Clinically Significant Psychotropic Drug-Drug Interactions in the Primary Care Setting
English, Brett A., Dortch, Marcus, Ereshefsky, Larry, Jhee, Stanford
Published in Current psychiatry reports (01.08.2012)
Published in Current psychiatry reports (01.08.2012)
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The role of fMRI in drug development
Carmichael, Owen, Schwarz, Adam J., Chatham, Christopher H., Scott, David, Turner, Jessica A., Upadhyay, Jaymin, Coimbra, Alexandre, Goodman, James A., Baumgartner, Richard, English, Brett A., Apolzan, John W., Shankapal, Preetham, Hawkins, Keely R.
Published in Drug discovery today (01.02.2018)
Published in Drug discovery today (01.02.2018)
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Tachycardia, reduced vagal capacity, and age-dependent ventricular dysfunction arising from diminished expression of the presynaptic choline transporter
English, Brett A, Appalsamy, Martin, Diedrich, Andre, Ruggiero, Alicia M, Lund, David, Wright, Jane, Keller, Nancy R, Louderback, Katherine M, Robertson, David, Blakely, Randy D
Published in American journal of physiology. Heart and circulatory physiology (01.09.2010)
Published in American journal of physiology. Heart and circulatory physiology (01.09.2010)
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Safety, Pharmacokinetics, and Efficacy of Olorinab, a Peripherally Acting, Highly Selective, Full Agonist of the Cannabinoid Receptor 2, in a Phase 2a Study of Patients With Chronic Abdominal Pain Associated With Crohn’s Disease
Yacyshyn, Bruce R, Hanauer, Stephen, Klassen, Preston, English, Brett A, Stauber, Kathe, Barish, Charles F, Gilder, Kye, Turner, Stewart, Higgins, Peter D R
Published in Crohn's & colitis 360 (01.01.2021)
Published in Crohn's & colitis 360 (01.01.2021)
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Use of translational pharmacodynamic biomarkers in early-phase clinical studies for schizophrenia
English, Brett A, Thomas, Kelan, Johnstone, Jack, Bazih, Adam, Gertsik, Lev, Ereshefsky, Larry
Published in Biomarkers in medicine (01.01.2014)
Published in Biomarkers in medicine (01.01.2014)
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Genetic variation in alpha2-adrenoreceptors and heart rate recovery after exercise
Kohli, Utkarsh, Diedrich, André, Kannankeril, Prince J, Muszkat, Mordechai, Sofowora, Gbenga G, Hahn, Maureen K, English, Brett A, Blakely, Randy D, Stein, C Michael, Kurnik, Daniel
Published in Physiological genomics (01.09.2015)
Published in Physiological genomics (01.09.2015)
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EFFECTS OF SCOPOLAMINE ON WORKING MEMORY TASK AND RESTING FUNCTIONAL CONNECTIVITY USING FMRI IN HEALTHY KOREAN SUBJECTS
English, Brett A, Osimo, Niki, Korb, Alex, Bazih, Adam, Rodriguez, Cameron, Sotomayor, Byron, Gertsik, Lev, Ereshefsky, Larry
Published in Alzheimer's & dementia (01.07.2014)
Published in Alzheimer's & dementia (01.07.2014)
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Genetic variation in the presynaptic norepinephrine transporter is associated with blood pressure responses to exercise in healthy humans
Kohli, Utkarsh, Hahn, Maureen K, English, Brett A, Sofowora, Gbenga G, Muszkat, Mordechai, Li, Chun, Blakely, Randy D, Stein, C Michael, Kurnik, Daniel
Published in Pharmacogenetics and genomics (01.04.2011)
Published in Pharmacogenetics and genomics (01.04.2011)
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Journal Article
Choline transporter gene variation is associated with attention-deficit hyperactivity disorder
English, Brett A, Hahn, Maureen K, Gizer, Ian R, Mazei-Robison, Michelle, Steele, Angela, Kurnik, Daniel M, Stein, Mark A, Waldman, Irwin D, Blakely, Randy D
Published in Journal of neurodevelopmental disorders (01.12.2009)
Published in Journal of neurodevelopmental disorders (01.12.2009)
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A placebo-controlled study of nefazodone for the treatment of chronic posttraumatic stress disorder: a preliminary study
Davis, Lori L, Jewell, Michele E, Ambrose, Sandra, Farley, Jason, English, Brett, Bartolucci, Al, Petty, Frederick
Published in Journal of clinical psychopharmacology (01.06.2004)
Published in Journal of clinical psychopharmacology (01.06.2004)
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P139 OLORINAB, A PERIPHERALLY RESTRICTED, HIGHLY SELECTIVE AGONIST OF THE CANNABINOID RECEPTOR TYPE 2 FOR THE MANAGEMENT OF VISCERAL PAIN IN INFLAMMATORY BOWEL DISEASE (IBD) – PRECLINICAL AND EARLY CLINICAL DEVELOPMENT
Lindstrom, Beatriz F., Ruckle, Jon L., Turner, Stewart A., Stauber, Kathe, Brierley, Stuart M., English, Brett A., Yacyshyn, Bruce
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2019)
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Journal Article
P139 OLORINAB, A PERIPHERALLY RESTRICTED, HIGHLY SELECTIVE AGONIST OF THE CANNABINOID RECEPTOR TYPE 2 FOR THE MANAGEMENT OF VISCERAL PAIN IN INFLAMMATORY BOWEL DISEASE (IBD) – PRECLINICAL AND EARLY CLINICAL DEVELOPMENT
Lindstrom, Beatriz F, Ruckle, Jon L, Turner, Stewart A, Stauber, Kathe, Brierley, Stuart M, English, Brett A, Yacyshyn, Bruce
Published in Inflammatory bowel diseases (07.02.2019)
Published in Inflammatory bowel diseases (07.02.2019)
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Su1930 – Safety and Efficacy of Olorinab, a Peripherally Restricted, Highly Selective, Cannabinoid Receptor 2 Agonist in a Phase 2A Study in Chronic Abdominal Pain Associated with Crohn’s Disease
Yacyshyn, Bruce, Ginsberg, Daniel C., Gilder, Kye, Walsh, Brandon, English, Brett, Turner, Stewart A., Klassen, Preston, Hanauer, Stephen B., Barish, Charles F., Higgins, Peter D.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
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Journal Article
Genetic variation in alpha sub(2)-adrenoreceptors and heart rate recovery after exercise
Kohli, Utkarsh, Diedrich, Andre, Kannankeril, Prince J, Muszkat, Mordechai, Sofowora, Gbenga G, Hahn, Maureen K, English, Brett A, Blakely, Randy D, Stein, C Michael, Kurnik, Daniel
Published in Physiological genomics (01.09.2015)
Published in Physiological genomics (01.09.2015)
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Journal Article
Genetic variation in alpha 2 -adrenoreceptors and heart rate recovery after exercise
Kohli, Utkarsh, Diedrich, André, Kannankeril, Prince J., Muszkat, Mordechai, Sofowora, Gbenga G., Hahn, Maureen K., English, Brett A., Blakely, Randy D., Stein, C. Michael, Kurnik, Daniel
Published in Physiological genomics (01.09.2015)
Published in Physiological genomics (01.09.2015)
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