Upadacitinib pharmacokinetics and exposure‐response analyses of efficacy and safety in psoriatic arthritis patients – Analyses of phase III clinical trials
Muensterman, Elena, Engelhardt, Benjamin, Gopalakrishnan, Sathej, Anderson, Jaclyn K., Mohamed, Mohamed‐Eslam F.
Published in Clinical and translational science (01.01.2022)
Published in Clinical and translational science (01.01.2022)
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Journal Article
A Bayesian approach to estimating hidden variables as well as missing and wrong molecular interactions in ordinary differential equation-based mathematical models
Engelhardt, Benjamin, Kschischo, Maik, Fröhlich, Holger
Published in Journal of the Royal Society interface (01.06.2017)
Published in Journal of the Royal Society interface (01.06.2017)
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Journal Article
Model Informed Dosing Regimen and Phase I Results of the Anti‐PD‐1 Antibody Budigalimab (ABBV‐181)
Powderly, John, Spira, Alexander, Kondo, Shunsuke, Doi, Toshihiko, Luke, Jason J., Rasco, Drew, Gao, Bo, Tanner, Minna, Cassier, Philippe A., Gazzah, Anas, Italiano, Antoine, Tosi, Diego, Afar, Daniel E., Parikh, Apurvasena, Engelhardt, Benjamin, Englert, Stefan, Lambert, Stacie L., Kasichayanula, Sreeneeranj, Mensing, Sven, Menon, Rajeev, Vosganian, Gregory, Tolcher, Anthony
Published in Clinical and translational science (01.01.2021)
Published in Clinical and translational science (01.01.2021)
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Journal Article
Dose optimization and exposure-response analyses to support optimal dose of ABBV-400, a novel C-met–targeting antibody drug conjugate, in patients with metastatic colorectal cancer (mCRC)
Biesdorf de Almeida, Carla, Engelhardt, Benjamin, Babel, Heiko, Badillo, Jesus D, Sharma, Manish, Powderly, John D., Neagu Aristide, Martha Raluca, Freise, Kevin Jay, Mensing, Sven, Parikh, Apurvasena
Published in Journal of clinical oncology (01.06.2024)
Published in Journal of clinical oncology (01.06.2024)
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Journal Article
Exposure-response relationships of venetoclax in combination with carfilzomib and dexamethasone in relapsed/refractory t(11;14) multiple myeloma patients
Badawi, Mohamed Ali, Engelhardt, Benjamin, Dobkowska, Edyta, Deng, Rong, Kaufman, Jonathan L, Menon, Rajeev, Salem, Ahmed Hamed
Published in Investigational new drugs (10.10.2024)
Published in Investigational new drugs (10.10.2024)
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Journal Article
Learning (from) the errors of a systems biology model
Engelhardt, Benjamin, Frőhlich, Holger, Kschischo, Maik
Published in Scientific reports (11.02.2016)
Published in Scientific reports (11.02.2016)
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Journal Article
Dosing of Venetoclax in Pediatric Patients with Relapsed Acute Myeloid Leukemia: Analysis of Developmental Pharmacokinetics and Exposure-Response Relationships
Badawi, Mohamed, Gopalakrishnan, Sathej, Engelhardt, Benjamin, Palenski, Tammy, Karol, Seth E., Rubnitz, Jeffrey E., Menon, Rajeev, Salem, Ahmed Hamed
Published in Clinical therapeutics (01.10.2024)
Published in Clinical therapeutics (01.10.2024)
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Journal Article
P-229 Exposure-response analysis of venetoclax in combination with carfilzomib and dexamethasone in t(11;14)-positive relapsed/refractory multiple myeloma patients
Badawi, Mohamed, Engelhardt, Benjamin, Dobkowska, Edyta, Deng, Rong, Kaufman, Jonathan, Menon, Rajeev, Salem, Ahmed Hamed
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
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Journal Article
Exposure-Response Analysis Supports a Lower Dose of Venetoclax in t(11;14)-Positive Relapsed/Refractory Multiple Myeloma Patients When Combined with Daratumumab and Dexamethasone
Badawi, Mohamed A, Engelhardt, Benjamin, Badillo, Jesus, Suleiman, Ahmed Abbas, Lash Fleming, Leanne, Luo, Yan, Kaufman, Jonathan L., Bahlis, Nizar Jacques, Menon, Rajeev, Salem, Ahmed Hamed
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Use of Clinical Trial Simulations to Compare the Performance of Different Approaches for Population Analyses of Pediatric Pharmacokinetic Data
Temrikar, Zaid, Muensterman, Elena, Engelhardt, Benjamin, Mohamed, Mohamed-Eslam F
Published in Journal of clinical pharmacology (01.07.2023)
Published in Journal of clinical pharmacology (01.07.2023)
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Journal Article
Proposed Scheme for Dosing Venetoclax in Pediatric Patients with Relapsed/Refractory Acute Myeloid Leukemia: Analysis of Developmental Pharmacokinetics and Exposure-Response Relationships
Badawi, Mohamed A, Gopalakrishnan, Sathej, Engelhardt, Benjamin, Palenski, Tammy L., Kim, Su Young, Karol, Seth E., Rubnitz, Jeffrey E., Menon, Rajeev, Salem, Ahmed Hamed
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Venetoclax in biomarker‐selected multiple myeloma patients: Impact of exposure on clinical efficacy and safety
Badawi, Mohamed, Coppola, Sheryl, Eckert, Doerthe, Gopalakrishnan, Sathej, Engelhardt, Benjamin, Doelger, Eva, Huang, Weize, Dobkowska, Edyta, Kumar, Shaji, Menon, Rajeev M., Salem, Ahmed Hamed
Published in Hematological oncology (01.01.2024)
Published in Hematological oncology (01.01.2024)
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Journal Article
Modelling and mathematical analysis of the M$_{2}$ receptor-dependent joint signalling and secondary messenger network in CHO cells
Engelhardt, Benjamin, Holze, Janine, Elliott, Christina, Baillie, George S, Kschischo, Maik, Fröhlich, Holger
Published in Mathematical medicine and biology (11.09.2018)
Published in Mathematical medicine and biology (11.09.2018)
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Journal Article
MDS-090: Semi-Mechanistic Model to Aid Clinical Understanding of Myelodysplastic Syndromes
Thakre, Neha, Maier, Corinna, Zha, Jiuhong, Menon, Rajeev, Engelhardt, Benjamin, Wolff, Johannes, Garcia-Manero, Guillermo, Wei, Andrew, Miles, Dale, Mensing, Sven, Gopalakrishnan, Sathej
Published in Clinical lymphoma, myeloma and leukemia (01.09.2020)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2020)
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Journal Article
COMBINATIONS WITH AN ANTI HUMAN CD39 ANTIBODY, AN ANTI HUMAN PD-1 ANTIBODY, AND CHEMOTHERAPY IN GASTRIC CANCER
Beers, Courtney, Lerner, Alana, Polepally, Akshanth R, Afar, Daniel E.H, Moon, Peter S, Moesta, Achim, Engelhardt, Benjamin, Karakunnel, Joyson
Year of Publication 09.05.2024
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Year of Publication 09.05.2024
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