Persistent Fibroadipogenic Progenitor Expansion Following Transient DUX4 Expression Provokes a Profibrotic State in a Mouse Model for FSHD
Bosnakovski, Darko, Oyler, David, Mitanoska, Ana, Douglas, Madison, Ener, Elizabeth T, Shams, Ahmed S, Kyba, Michael
Published in International journal of molecular sciences (11.02.2022)
Published in International journal of molecular sciences (11.02.2022)
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Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma
Bosnakovski, Darko, Ener, Elizabeth T., Cooper, Mark S., Gearhart, Micah D., Knights, Kevin A., Xu, Natalie C., Palumbo, Christian A., Toso, Erik A., Marsh, Graham P., Maple, Hannah J., Kyba, Michael
Published in Oncogenesis (New York, NY) (12.10.2021)
Published in Oncogenesis (New York, NY) (12.10.2021)
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Journal Article
Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein
Bosnakovski, Darko, Toso, Erik A., Ener, Elizabeth T., Gearhart, Micah D., Yin, Lulu, Lüttmann, Felipe F., Magli, Alessandro, Shi, Ke, Kim, Johnny, Aihara, Hideki, Kyba, Michael
Published in iScience (20.10.2023)
Published in iScience (20.10.2023)
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Journal Article
Transcriptional and cytopathological hallmarks of FSHD in chronic DUX4-expressing mice
Bosnakovski, Darko, Shams, Ahmed S, Yuan, Ce, da Silva, Meiricris T, Ener, Elizabeth T, Baumann, Cory W, Lindsay, Angus J, Verma, Mayank, Asakura, Atsushi, Lowe, Dawn A, Kyba, Michael
Published in The Journal of clinical investigation (01.05.2020)
Published in The Journal of clinical investigation (01.05.2020)
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Low level DUX4 expression disrupts myogenesis through deregulation of myogenic gene expression
Bosnakovski, Darko, Gearhart, Micah D., Toso, Erik A., Ener, Elizabeth T., Choi, Si Ho, Kyba, Michael
Published in Scientific reports (16.11.2018)
Published in Scientific reports (16.11.2018)
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A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression, and cell death
Bosnakovski, Darko, da Silva, Meiricris T, Sunny, Sithara T, Ener, Elizabeth T, Toso, Erik A, Yuan, Ce, Cui, Ziyou, Walters, Michael A, Jadhav, Ajit, Kyba, Michael
Published in Science advances (01.09.2019)
Published in Science advances (01.09.2019)
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Journal Article
Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein
Bosnakovski, Darko, Toso, Erik A, Ener, Elizabeth T, Gearhart, Micah D, Yin, Lulu, Lüttmann, Felipe F, Magli, Alessandro, Shi, Ke, Kim, Johnny, Aihara, Hideki, Kyba, Michael
Published in bioRxiv (22.01.2023)
Published in bioRxiv (22.01.2023)
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