GATA4 loss of function in liver cancer impedes precursor to hepatocyte transition
Enane, Francis O, Shuen, Wai Ho, Gu, Xiaorong, Quteba, Ebrahem, Przychodzen, Bartlomiej, Makishima, Hideki, Bodo, Juraj, Ng, Joanna, Chee, Chit Lai, Ba, Rebecca, Seng Koh, Lip, Lim, Janice, Cheong, Rachael, Teo, Marissa, Hu, Zhenbo, Ng, Kwok Peng, Maciejewski, Jaroslaw, Radivoyevitch, Tomas, Chung, Alexander, Ooi, London Lucien, Tan, Yu Meng, Cheow, Peng-Chung, Chow, Pierce, Chan, Chung Yip, Lim, Kiat Hon, Yerian, Lisa, Hsi, Eric, Toh, Han Chong, Saunthararajah, Yogen
Published in The Journal of clinical investigation (01.09.2017)
Published in The Journal of clinical investigation (01.09.2017)
Get full text
Journal Article
PBRM1 loss in kidney cancer unbalances the proximal tubule master transcription factor hub to repress proximal tubule differentiation
Gu, Xiaorong, Enane, Francis, Tohme, Rita, Schuerger, Caroline, Radivoyevitch, Tomas, Parker, Yvonne, Zuberi, Eric, Przychodzen, Bartlomiej, Jha, Babal Kant, Lindner, Daniel, Rini, Brian, Saunthararajah, Yogen
Published in Cell reports (Cambridge) (21.09.2021)
Published in Cell reports (Cambridge) (21.09.2021)
Get full text
Journal Article
Automation of high-throughput mRNA-seq library preparation: a robust, hands-free and time efficient methodology
Santacruz, Diana, Enane, Francis O, Fundel-Clemens, Katrin, Giner, Martin, Wolf, Gernot, Onstein, Svenja, Klimek, Christoph, Smith, Zachary, Wijayawardena, Bhagya, Viollet, Coralie
Published in SLAS discovery (01.03.2022)
Published in SLAS discovery (01.03.2022)
Get full text
Journal Article
Corrigendum to “Automation of high-throughput mRNA-seq library preparation: a robust, hands-free and time efficient methodology” [SLAS Discovery, Volume 27 (2022) P140-147/2472-5552]
Santacruz, Diana, Enane, Francis O, Fundel-Clemens, Katrin, Giner, Martin, Wolf, Gernot, Onstein, Svenja, Klimek, Christoph, Smith, Zachary, Wijayawardena, Bhagya, Viollet, Coralie
Published in SLAS discovery (01.07.2024)
Published in SLAS discovery (01.07.2024)
Get full text
Journal Article
Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates
Gu, Xiaorong, Ebrahem, Quteba, Mahfouz, Reda Z, Hasipek, Metis, Enane, Francis, Radivoyevitch, Tomas, Rapin, Nicolas, Przychodzen, Bartlomiej, Hu, Zhenbo, Balusu, Ramesh, Cotta, Claudiu V, Wald, David, Argueta, Christian, Landesman, Yosef, Martelli, Maria Paola, Falini, Brunangelo, Carraway, Hetty, Porse, Bo T, Maciejewski, Jaroslaw, Jha, Babal K, Saunthararajah, Yogen
Published in The Journal of clinical investigation (01.10.2018)
Published in The Journal of clinical investigation (01.10.2018)
Get full text
Journal Article
Abstract 1088: Advancing non-cytotoxic DNMT1-targeting to treat chemorefractory pancreatic cancer
Tohme, Rita, Enane, Francis, Schuerger, Caroline, Gu, Xiaorong, Fishel, Melissa, Pink, John, Lindner, Daniel, Sohal, Davendra, Saunthararajah, Yogen
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Get full text
Journal Article
Abstract 3520: PBRM1 inactivation in renal cell cancer alters master transcription factor hub composition to repress instead of activate epithelial-differentiation
Gu, Xiaorong, Enane, Francis, Mahfouz, Reda, Radivoyevitch, Tomas, Przychodzen, Bartlomiej, Parker, Yvonne, Lindner, Daniel, Rini, Brian, Saunthararajah, Yogen
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Get full text
Journal Article
Corrigendum to "Automation of high-throughput mRNA-seq library preparation: a robust, hands-free and time efficient methodology" SLAS Discovery, Volume 27 (2022) P140-147/2472-5552
Santacruz, Diana, Enane, Francis O, Fundel-Clemens, Katrin, Giner, Martin, Wolf, Gernot, Onstein, Svenja, Klimek, Christoph, Smith, Zachary, Wijayawardena, Bhagya, Viollet, Coralie
Published in SLAS discovery (01.07.2024)
Published in SLAS discovery (01.07.2024)
Get full text
Journal Article
Abstract 2872: Cytoplasmic localization of PU.1 with mutated NPM1 causes myeloid differentiation arrest
Gu, Xiaorong, Mahfouz, Reda, Zhang, Ji, Enane, Francis, Hu, Zhenbo, Radivoyevitch, Tomas, Wald, David, Martelli, Maria Paola, Falini, Brunangelo, Landesman, Yosef, Maciejewski, Jaroslaw, Saunthararajah, Yogen
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Get full text
Journal Article
The Mechanism By Which Mutant Nucleophosmin (NPM1) Creates Leukemic Self-Renewal Is Readily Reversed
Gu, Xiaorong, Mahfouz, Reda Z., Ebrahem, Quteba, Enane, Francis, Radivoyevitch, Tomas, Clemente, Michael J., Przychodzen, Bartlomiej P, Hu, Zhenbo, Balusu, Ramesh, Cotta, Claudiu V., Wald, David N., Landesman, Yosef, Martelli, Maria Paola, Falini, Brunangelo, Maciejewski, Jaroslaw P, Saunthararajah, Yogenthiran
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
Get full text
Journal Article
The Mechanisms By Which Mutant-NPM1 Uncouples Differentiation from Proliferation Are Reversed By Several Drugs, Enabling Rational Multi-Component Non-Cytotoxic Differentiation Therapy
Gu, Xiaorong, Ebrahem, Quteba, Mahfouz, Reda Z., Hasipek, Metis, Enane, Francis, Radivoyevitch, Tomas, Rapin, Nicolas, Przychodzen, Bartlomiej P., Balusu, Ramesh, Cotta, Claudiu V, Wald, David, Hu, Zhenbo, Landesman, Yosef, Martelli, Maria Paola, Falini, Brunangelo, Carraway, Hetty E., Maciejewski, Jaroslaw P., Jha, Babal K, Saunthararajah, Yogenthiran
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
Get full text
Journal Article
PHF6 - Somatic Mutations and Their Role in Pathophysiology of MDS and AML
Przychodzen, Bartlomiej, Gu, Xiaorong, You, Dewen, Hirsch, Cassandra M., Clemente, Michael J., Viny, Aaron D., Levine, Ross L., Haferlach, Torsten, Maggendorfer, Manja, Sekeres, Mikkael A., Carraway, Hetty E., Nazha, Aziz, Enane, Francis, Maciejewski, Jaroslaw P.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
Get full text
Journal Article
A Specific Mechanism By Which NPM1 mutations Impede Myeloid Differentiation Also Explains The Link With DNMT3A Mutation
Gu, Xiaorong, Mahfouz, Reda Z, Enane, Francis, Hu, Zhenbo, Clemente, Michael J., Przychodzen, Bartlomiej P, Sekeres, Mikkael A., Advani, Anjali S., Kalaycio, Matt, Maciejewski, Jaroslaw P., Saunthararajah, Yogen
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
Get full text
Journal Article
Translational significance of a newly identified hepatocellular carcinoma tumor suppressor gene on chromosome 8p
Toh, Han Chong, Enane, Francis, Teo, Marissa, Makishima, Hideki, Ng, JoAnna, Chee, Chit Lai, Ang, Soo Fan, Lim, Kiat Hon, Saunthararajah, Yogen
Published in Journal of clinical oncology (20.05.2013)
Published in Journal of clinical oncology (20.05.2013)
Get full text
Journal Article
Abstract 3518: Frequent mutation and deletion of GATA4 in hepatocellular carcinoma represses proliferation terminating late-maturation genes CEBPD and HNF4A by reversible epigenetic mechanisms
Enane, Francis O., Teo, Marissa, Makishima, Hideki, Hu, Zhenbo, Toh, Han Chong, Saunthararajah, Yogen, Ng, Joanna, Lai, Chit, Ang, Soo Fan, Hon, Lim Kiat
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Get full text
Journal Article