Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics
Schoch, Angela, Kettenberger, Hubert, Mundigl, Olaf, Winter, Gerhard, Engert, Julia, Heinrich, Julia, Emrich, Thomas
Published in Proceedings of the National Academy of Sciences - PNAS (12.05.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (12.05.2015)
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Journal Article
STN7 is not essential for developmental acclimation of Arabidopsis to light intensity
Flannery, Sarah E., Pastorelli, Federica, Emrich‐Mills, Thomas Z., Casson, Stuart A., Hunter, C. Neil, Dickman, Mark J., Jackson, Philip J., Johnson, Matthew P.
Published in The Plant journal : for cell and molecular biology (01.06.2023)
Published in The Plant journal : for cell and molecular biology (01.06.2023)
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A Two-pronged Binding Mechanism of IgG to the Neonatal Fc Receptor Controls Complex Stability and IgG Serum Half-life
Jensen, Pernille Foged, Schoch, Angela, Larraillet, Vincent, Hilger, Maximiliane, Schlothauer, Tilman, Emrich, Thomas, Rand, Kasper Dyrberg
Published in Molecular & cellular proteomics (01.03.2017)
Published in Molecular & cellular proteomics (01.03.2017)
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Journal Article
A multiplex real-time PCR assay for rapid detection and differentiation of 25 bacterial and fungal pathogens from whole blood samples
Lehmann, Lutz Eric, Hunfeld, Klaus-Peter, Emrich, Thomas, Haberhausen, Gerd, Wissing, Heimo, Hoeft, Andreas, Stüber, Frank
Published in Medical microbiology and immunology (01.09.2008)
Published in Medical microbiology and immunology (01.09.2008)
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A novel approach to investigate the effect of methionine oxidation on pharmacokinetic properties of therapeutic antibodies
Stracke, Jan, Emrich, Thomas, Rueger, Petra, Schlothauer, Tilman, Kling, Lothar, Knaupp, Alexander, Hertenberger, Hubert, Wolfert, Andreas, Spick, Christian, Lau, Wilma, Drabner, Georg, Reiff, Ulrike, Koll, Hans, Papadimitriou, Apollon
Published in mAbs (03.09.2014)
Published in mAbs (03.09.2014)
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Journal Article
Analytical FcRn affinity chromatography for functional characterization of monoclonal antibodies
Schlothauer, Tilman, Rueger, Petra, Stracke, Jan Olaf, Hertenberger, Hubert, Fingas, Felix, Kling, Lothar, Emrich, Thomas, Drabner, Georg, Seeber, Stefan, Auer, Johannes, Koch, Stefan, Papadimitriou, Apollon
Published in mAbs (01.07.2013)
Published in mAbs (01.07.2013)
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Journal Article
Antibody variable sequences have a pronounced effect on cellular transport and plasma half-life
Grevys, Algirdas, Frick, Rahel, Mester, Simone, Flem-Karlsen, Karine, Nilsen, Jeannette, Foss, Stian, Sand, Kine Marita Knudsen, Emrich, Thomas, Fischer, Jens Andre Alexander, Greiff, Victor, Sandlie, Inger, Schlothauer, Tilman, Andersen, Jan Terje
Published in iScience (18.02.2022)
Published in iScience (18.02.2022)
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Specific immune modulation of experimental colitis drives enteric alpha-synuclein accumulation and triggers age-related Parkinson-like brain pathology
Grathwohl, Stefan, Quansah, Emmanuel, Maroof, Nazia, Steiner, Jennifer A, Spycher, Liz, Benmansour, Fethalla, Duran-Pacheco, Gonzalo, Siebourg-Polster, Juliane, Oroszlan-Szovik, Krisztina, Remy, Helga, Haenggi, Markus, Stawiski, Marc, Selhausen, Matthias, Mailver, Pierre, Wolfert, Andreas, Emrich, Thomas, Madaj, Zachary, Su, Arel, Escobar Galvis, Martha L, Mueller, Christoph, Herrmann, Annika, Brundin, Patrik, Britschgi, Markus
Published in Free Neuropathology (18.05.2021)
Published in Free Neuropathology (18.05.2021)
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Journal Article
Determination of critical quality attributes for monoclonal antibodies using quality by design principles
Alt, Nadja, Zhang, Taylor Y., Motchnik, Paul, Taticek, Ron, Quarmby, Valerie, Schlothauer, Tilman, Beck, Hermann, Emrich, Thomas, Harris, Reed J.
Published in Biologicals (01.09.2016)
Published in Biologicals (01.09.2016)
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Journal Article
Low immunogenicity of emicizumab in persons with haemophilia A
Schmitt, Christophe, Emrich, Thomas, Chebon, Sammy, Fernandez, Elena, Petry, Claire, Yoneyama, Koichiro, Kiialainen, Anna, Howard, Monet, Niggli, Markus, Paz‐Priel, Ido, Chang, Tiffany
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2021)
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01.11.2021)
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Journal Article
Analysis of human telomerase reverse transcriptase mRNA (hTERT) expression in myxoid liposarcomas using LightCycler real-time quantitative reverse transcriptase-polymerase chain reaction
Schneider-Stock, Regine, Emrich, Thomas, Peters, Brigitte, Jaeger, Viola, Roessner, Albert
Published in Electrophoresis (01.04.2001)
Published in Electrophoresis (01.04.2001)
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Journal Article
Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity
Sum, Eva, Rapp, Moritz, Fröbel, Philipp, Le Clech, Marine, Dürr, Harald, Giusti, Anna Maria, Perro, Mario, Speziale, Dario, Kunz, Leo, Menietti, Elena, Brünker, Peter, Hopfer, Ulrike, Lechmann, Martin, Sobieniecki, Andrzej, Appelt, Birte, Adelfio, Roberto, Nicolini, Valeria, Freimoser-Grundschober, Anne, Jordaan, Whitney, Labiano, Sara, Weber, Felix, Emrich, Thomas, Christen, François, Essig, Birgit, Romero, Pedro, Trumpfheller, Christine, Umaña, Pablo
Published in Clinical cancer research (15.07.2021)
Published in Clinical cancer research (15.07.2021)
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Quantitative polymerase chain reaction in the bioanalytical laboratory and technical and scientific considerations for nonclinical and clinical assay characterization, validation and sample analysis
Laurén, Anna, Braun, Manuela, Cazzin, Chiara, Colleti, Kelly, Cox, Chris, Dietz, Lisa, Emrich, Thomas, Geddes, Kristin, Herr, Kate, Iles, Tracy, Rogue, Alexandra, Verlinden, Yvan, Timmerman, Philip
Published in Bioanalysis (01.08.2022)
Published in Bioanalysis (01.08.2022)
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메타버스 콘텐츠 모달리티 매핑
EMRICH THOMAS, BENTON RIGEL GARETH, MURPHY CHUTORIAN ERIK, BARTSCHAT CHRISTOPH MICHAEL, UDWIN JOEL, BUTKO NICHOLAS
Year of Publication 18.07.2024
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Year of Publication 18.07.2024
Patent
2019 White Paper on Recent Issues in Bioanalysis: FDA Immunogenicity Guidance, Gene Therapy, Critical Reagents, Biomarkers and Flow Cytometry Validation (Part 3 – Recommendations on 2019 FDA Immunogenicity Guidance, Gene Therapy Bioanalytical Challenges, Strategies for Critical Reagent Management, Biomarker Assay Validation, Flow Cytometry Validation & CLSI H62)
Piccoli, Steven, Mehta, Devangi, Vitaliti, Alessandra, Allinson, John, Amur, Shashi, Eck, Steve, Green, Cherie, Hedrick, Michael, Hopper, Shirley, Ji, Allena, Joyce, Alison, Litwin, Virginia, Maher, Kevin, Mathews, Joel, Peng, Kun, Safavi, Afshin, Wang, Yow-Ming, Zhang, Yan, Amaravadi, Lakshmi, Palackal, Nisha, Thankamony, Sai, Beaver, Chris, Bame, Eris, Emrich, Thomas, Grimaldi, Christine, Haulenbeek, Jonathan, Kakkanaiah, Vellalore, Lanham, David, Mayer, Andrew, Trampont, Paul C, Vermet, Laurent, Dakappagari, Naveen, Fleener, Catherine, Garofolo, Fabio, Rogers, Cynthia, Tangri, Shabnam, Xu, Yuanxin, Liang, Meina, Rajadhyaksha, Manoj, Richards, Susan, Schweighardt, Becky, Purushothama, Shobha, Baltrukonis, Daniel, Brumm, Jochen, Cherry, Elana, Delcarpini, Jason, Gleason, Carol, Kirshner, Susan, Kubiak, Robert, Pan, Luying, Partridge, Michael, Pedras-Vasconcelos, João, Qu, Qiang, Skibeli, Venke, Saunders, Therese Solstad, Staack, Roland F, Stubenrauch, Kay, Torri, Al, Verthelyi, Daniela, Yan, Haoheng, Gorovits, Boris, Palmer, Rachel, Milton, Mark, Long, Brian, Corsaro, Bart, Farrokhi, Vahid, Fiscella, Michele, Henderson, Neil, Jawa, Vibha, McNally, Jim, Murphy, Rocio, Waldner, Hanspeter, Yang, Tong-Yuan
Published in Bioanalysis (01.12.2019)
Published in Bioanalysis (01.12.2019)
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Comparative assessment of immune complex-mediated hypersensitivity reactions with biotherapeutics in the non-human primate: Critical parameters, safety and lessons for future studies
Kronenberg, Sven, Husar, Elisabeth, Schubert, Christine, Freichel, Christian, Emrich, Thomas, Lechmann, Martin, Giusti, Anna Maria, Regenass, Franziska
Published in Regulatory toxicology and pharmacology (01.08.2017)
Published in Regulatory toxicology and pharmacology (01.08.2017)
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