Investigation of α‐glucosidase and α‐amylase inhibitory effects of phenoxy chalcones and molecular modeling studies
Kurşun‐Aktar, Bedriye Seda, Adem, Şevki, Tatar‐Yilmaz, Gizem, Hameed, Zeyad Adıl Hameed, Oruç‐Emre, Emine Elçin
Published in Journal of molecular recognition (01.11.2023)
Published in Journal of molecular recognition (01.11.2023)
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Journal Article
Chalcones bearing nitrogen‐containing heterocyclics as multi‐targeted inhibitors: Design, synthesis, biological evaluation and molecular docking studies
Sıcak, Yusuf, Kekeçmuhammed, Hüseyin, Karaküçük‐İyidoğan, Ayşegül, Taşkın‐Tok, Tuğba, Oruç‐Emre, Emine Elçin, Öztürk, Mehmet
Published in Journal of molecular recognition (01.07.2023)
Published in Journal of molecular recognition (01.07.2023)
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Journal Article
Design, in Silico Studies and Biological Evaluation of New Chiral Thiourea and 1,3‐Thiazolidine‐4,5‐dione Derivatives
Evyapan, Samet, Oruç‐Emre, Emine Elçin, Sıcak, Yusuf, Karaküçük‐İyidoğan, Ayşegül, Yılmaz, Gizem Tatar, Öztürk, Mehmet
Published in Chemistry & biodiversity (01.08.2023)
Published in Chemistry & biodiversity (01.08.2023)
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Journal Article
Novel platinum(II) and palladium(II) complexes of thiosemicarbazones derived from 5-substitutedthiophene-2-carboxaldehydes and their antiviral and cytotoxic activities
Karaküçük-İyidoğan, Ayşegül, Taşdemir, Demet, Oruç-Emre, Emine Elçin, Balzarini, Jan
Published in European journal of medicinal chemistry (01.11.2011)
Published in European journal of medicinal chemistry (01.11.2011)
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Journal Article
Novel fluorine‐containing chiral hydrazide‐hydrazones: Design, synthesis, structural elucidation, antioxidant and anticholinesterase activity, and in silico studies
Sıcak, Yusuf, Oruç‐Emre, Emine Elçin, Öztürk, Mehmet, Taşkın‐Tok, Tuğba, Karaküçük‐Iyidoğan, Ayşegül
Published in Chirality (New York, N.Y.) (01.08.2019)
Published in Chirality (New York, N.Y.) (01.08.2019)
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Journal Article
Synthesis of novel chiral metal complexes derived from chiral thiosemicarbazide ligands as potential antioxidant agents
Başaran, Eyüp, Sıcak, Yusuf, Sogukomerogullari, Hatice Gamze, Karaküçük‐Iyidoğan, Ayşegül, Oruç‐Emre, Emine Elçin, Sönmez, Mehmet, Öztürk, Mehmet
Published in Chirality (New York, N.Y.) (01.06.2019)
Published in Chirality (New York, N.Y.) (01.06.2019)
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Journal Article
Synthesis of Novel Chiral Sulfonamide-Bearing 1,2,4-Triazole-3-thione Analogs Derived from D- and L-Phenylalanine Esters as Potential Anti-Influenza Agents
Başaran, Eyüp, Karaküçük-Iyidoğan, Ayşegül, Schols, Dominique, Oruç-Emre, Emine Elçin
Published in Chirality (New York, N.Y.) (01.06.2016)
Published in Chirality (New York, N.Y.) (01.06.2016)
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Journal Article
Design, Synthesis, Pharmacological Activities, Structure–Activity Relationship, and In Silico Studies of Novel 5‑Substituted-2-(morpholinoimino)-thiazolidin-4-ones
Sıcak, Yusuf, Aktar, Bedriye Seda Kurşun, Yılmaz, Gizem Tatar, Öztürk, Fatma Aydoğmuş, Öztürk, Mehmet, Tok, Tuğba Taşkın, Emre, Emine Elçin Oruç
Published in ACS omega (17.10.2023)
Published in ACS omega (17.10.2023)
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Journal Article
Synthesis, Molecular Modeling, and Biological Evaluation of Novel Chiral Thiosemicarbazone Derivatives as Potent Anticancer Agents
Taşdemir, Demet, Karaküçük-İyidoğan, Ayşegül, Ulaşli, Mustafa, Taşkin-Tok, Tuğba, Oruç-Emre, Emİne Elçİn, Bayram, Hasan
Published in Chirality (New York, N.Y.) (01.02.2015)
Published in Chirality (New York, N.Y.) (01.02.2015)
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Journal Article
Design and Synthesis of Novel Thioureas Derived from 4‐(4‐Fluorophenoxy)aniline as Anticancer Agents
Yıldız, İnci Nejla, Oruç‐Emre, Emine Elçin, Taşdemir, Demet, Karaküçük‐İyidoğan, Ayşegül, Ulaşlı, Mustafa, Bayram, Hasan
Published in Journal of the Chinese Chemical Society (Taipei) (01.03.2017)
Published in Journal of the Chinese Chemical Society (Taipei) (01.03.2017)
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Journal Article
Homoleptic metal complexes derived from hydrazones as ligand; synthesis, cytotoxic activity, photoluminescence properties and ADMET studies
Sarıoğlu, Ahmet Oral, Bulut, Zafer, Kahraman, Demet Taşdemir, Güler, Semih, Güngör, Özge, Karaküçük-İyidoğan, Ayşegül, Oruç-Emre, Emine Elçin
Published in Journal of molecular structure (05.05.2024)
Published in Journal of molecular structure (05.05.2024)
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Journal Article
Chiral thioureas containing naphthalene moiety as selective butyrylcholinesterase inhibitors: Design, synthesis, cholinesterase inhibition activity and molecular docking studies
Karaküçük-İyidoğan, Ayşegül, Sıcak, Yusuf, Uysal, Demet Begüm, Taşkın-Tok, Tuğba, Öztürk, Mehmet, Oruç-Emre, Emine Elçin
Published in Journal of molecular structure (05.01.2025)
Published in Journal of molecular structure (05.01.2025)
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Development of new chiral 1,2,4-triazole-3-thiones and 1,3,4-thiadiazoles with promising in vivo anticonvulsant activity targeting GABAergic system and voltage-gated sodium channels (VGSCs)
Karakucuk-Iyidogan, Aysegul, Basaran, Eyup, Tatar-Yilmaz, Gizem, Oruc-Emre, Emine Elcin
Published in Bioorganic chemistry (01.10.2024)
Published in Bioorganic chemistry (01.10.2024)
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Journal Article
New piperidine-hydrazone derivatives: Synthesis, biological evaluations and molecular docking studies as AChE and BChE inhibitors
Karaman, Nurcan, Sıcak, Yusuf, Taşkın-Tok, Tuğba, Öztürk, Mehmet, Karaküçük-İyidoğan, Ayşegül, Dikmen, Miris, Koçyiğit-Kaymakçıoğlu, Bedia, Oruç-Emre, Emine Elçin
Published in European journal of medicinal chemistry (29.11.2016)
Published in European journal of medicinal chemistry (29.11.2016)
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Journal Article
Synthesis of benzoyl hydrazones having 4-hydroxy-3,5-dimethoxy phenyl ring, their biological activities, and molecular modeling studies on enzyme inhibition activities
Kurşun Aktar, Bedriye Seda, Sicak, Yusuf, Tatar, Gizem, Oruç-Emre, Emine Elçin
Published in Turkish journal of chemistry (01.01.2022)
Published in Turkish journal of chemistry (01.01.2022)
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Journal Article
Experimental, spectroscopic and theoretical investigation of (+)-(R)-5-[1-(Benzenesulfonamido)-2-phenylethyl]-4-phenethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
Başaran, Eyüp, Demircioğlu, Zeynep, Tarı, Gonca Özdemir, Ceylan, Ümit, Karaküçük-İyidoğan, Ayşegül, Oruç-Emre, Emine Elçin, Aygün, Muhittin
Published in Journal of molecular structure (05.03.2022)
Published in Journal of molecular structure (05.03.2022)
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Journal Article
Designing heterocyclic chalcones, benzoyl/sulfonyl hydrazones: An insight into their biological activities and molecular docking study
Kurşun Aktar, Bedriye Seda, Sıcak, Yusuf, Tok, Tuğba Taşkın, Oruç-Emre, Emine Elçin, Yağlıoğlu, Ayse Şahin, Iyidoğan, Ayşegül Karaküçük, Öztürk, Mehmet, Demirtaş, Ibrahim
Published in Journal of molecular structure (05.07.2020)
Published in Journal of molecular structure (05.07.2020)
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Journal Article
Discovery of new chiral sulfonamides bearing benzoxadiazole as HIF inhibitors for non-small cell lung cancer therapy: design, microwave-assisted synthesis, binding affinity, in vitro antitumoral activities and in silico studies
Kahraman, Demet Tasdemir, Karakucuk-Iyidogan, Aysegul, Saygideger, Yasemin, Oruc-Emre, Emine Elcin, Taskin-Tok, Tugba, Basaran, Eyup, Ilhan, Sedat, Demir, Burcu Saygideger, Uren, Aykut, Bayram, Hasan
Published in New journal of chemistry (07.02.2022)
Published in New journal of chemistry (07.02.2022)
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