Drug Targeting of Plasminogen Activator Inhibitor-1 Inhibits Metabolic Dysfunction and Atherosclerosis in a Murine Model of Metabolic Syndrome
Khoukaz, Hekmat B, Ji, Yan, Braet, Drew J, Vadali, Manisha, Abdelhamid, Ahmed A, Emal, Cory D, Lawrence, Daniel A, Fay, William P
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2020)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2020)
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Journal Article
Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1
Li, Shih-Hon, Reinke, Ashley A, Sanders, Karen L, Emal, Cory D, Whisstock, James C, Stuckey, Jeanne A, Lawrence, Daniel A
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
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Journal Article
Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation
Tammaro, A., Kers, J., Emal, D., Stroo, I., Teske, G. J. D., Butter, L. M., Claessen, N., Damman, J., Derive, M., Navis, G., Florquin, S., Leemans, J. C., Dessing, M. C.
Published in Scientific reports (08.12.2016)
Published in Scientific reports (08.12.2016)
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Compartmentalized Actions of the Plasminogen Activator Inhibitors, PAI-1 and Nsp, in Ischemic Stroke
Torrente, Daniel, Su, Enming Joseph, Fredriksson, Linda, Warnock, Mark, Bushart, David, Mann, Kris M., Emal, Cory D., Lawrence, Daniel A.
Published in Translational stroke research (01.10.2022)
Published in Translational stroke research (01.10.2022)
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Structure-Activity Relationships for Inhibition of Cysteine Protease Activity and Development of Plasmodium falciparum by Peptidyl Vinyl Sulfones
SHENAI, Bhaskar R, LEE, Belinda J, ALVAREZ-HERNANDEZ, Alejandro, CHONG, Pek Y, EMAL, Cory D, NEITZ, R. Jeffrey, ROUSH, William R, ROSENTHAL, Philip J
Published in Antimicrobial Agents and Chemotherapy (01.01.2003)
Published in Antimicrobial Agents and Chemotherapy (01.01.2003)
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Characterization of a Novel Class of Polyphenolic Inhibitors of Plasminogen Activator Inhibitor-1
Cale, Jacqueline M., Li, Shih-Hon, Warnock, Mark, Su, Enming J., North, Paul R., Sanders, Karen L., Puscau, Maria M., Emal, Cory D., Lawrence, Daniel A.
Published in The Journal of biological chemistry (12.03.2010)
Published in The Journal of biological chemistry (12.03.2010)
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High-affinity binding of plasminogen-activator inhibitor 1 complexes to LDL receptor–related protein 1 requires lysines 80, 88, and 207
Migliorini, Mary, Li, Shih-Hon, Zhou, Anqi, Emal, Cory D., Lawrence, Daniel A., Strickland, Dudley K.
Published in The Journal of biological chemistry (03.01.2020)
Published in The Journal of biological chemistry (03.01.2020)
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Dual-reporter high-throughput screen for small-molecule in vivo inhibitors of plasminogen activator inhibitor type-1 yields a clinical lead candidate
Reinke, Ashley A., Li, Shih-Hon, Warnock, Mark, Shaydakov, Maxim E., Guntaka, Naga Sandhya, Su, Enming J., Diaz, Jose A., Emal, Cory D., Lawrence, Daniel A.
Published in The Journal of biological chemistry (01.02.2019)
Published in The Journal of biological chemistry (01.02.2019)
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Druggable Hot Spots in the Schistosomiasis Cathepsin B1 Target Identified by Functional and Binding Mode Analysis of Potent Vinyl Sulfone Inhibitors
Jílková, Adéla, Rubešová, Petra, Fanfrlík, Jindřich, Fajtová, Pavla, Řezáčová, Pavlína, Brynda, Jiří, Lepšík, Martin, Mertlíková-Kaiserová, Helena, Emal, Cory D, Renslo, Adam R, Roush, William R, Horn, Martin, Caffrey, Conor R, Mareš, Michael
Published in ACS infectious diseases (14.05.2021)
Published in ACS infectious diseases (14.05.2021)
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Outcomes of culture-negative vs. culture-positive infective endocarditis: the ESC-EORP EURO-ENDO registry
Kong, William K F, Salsano, Antonio, Giacobbe, Daniele Roberto, Popescu, Bogdan A, Laroche, Cécile, Duval, Xavier, Schueler, Robert, Moreo, Antonella, Colonna, Paolo, Piper, Cornelia, Calvo-Iglesias, Francisco, Badano, Luigi P, Srdanovic, Ilija, Boutoille, David, Huttin, Olivier, Stöhr, Elisabeth, Timóteo, Ana Teresa, Vaskelyte, Jolanta Justina, Sadeghpour, Anita, Tornos, Pilar, Abid, Leila, Poh, Kian Keong, Habib, Gilbert, Lancellotti, Patrizio
Published in European heart journal (01.08.2022)
Published in European heart journal (01.08.2022)
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Structure activity studies of a novel cytotoxic benzodiazepine
Boitano, Anthony, Emal, Cory D, Leonetti, Francesco, Blatt, Neal B, Dineen, Thomas A, Ellman, Jonathan A, Roush, William R, Opipari, Anthony W, Glick, Gary D
Published in Bioorganic & medicinal chemistry letters (06.10.2003)
Published in Bioorganic & medicinal chemistry letters (06.10.2003)
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Journal Article
High-affinity binding of plasminogen-activator inhibitor 1 complexes to LDL receptor-related protein 1 requires lysines 80, 88, and 207
Migliorini, Mary, Li, Shih-Hon, Zhou, Anqi, Emal, Cory D, Lawrence, Daniel A, Strickland, Dudley K
Published in The Journal of biological chemistry (03.01.2020)
Get full text
Published in The Journal of biological chemistry (03.01.2020)
Journal Article
Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1
Li, Shih-Hon, Reinke, Ashley A., Sanders, Karen L., Emal, Cory D., Whisstock, James C., Stuckey, Jeanne A., Lawrence, Daniel A.
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
Get full text
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2013)
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