In Silico Assessment of Efficacy and Safety of IKur Inhibitors in Chronic Atrial Fibrillation: Role of Kinetics and State-Dependence of Drug Binding
Ellinwood, Nicholas, Dobrev, Dobromir, Morotti, Stefano, Grandi, Eleonora
Published in Frontiers in pharmacology (07.11.2017)
Published in Frontiers in pharmacology (07.11.2017)
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Two heads are better than one: current landscape of integrating QSP and machine learning
Zhang Tongli, Androulakis, Ioannis P, Bonate, Peter, Cheng, Limei, Helikar Tomáš, Parikh Jaimit, Rackauckas Christopher, Subramanian Kalyanasundaram, Cho, Carolyn R, Borisov, Ivan, Broderick, Gordon, Damian Valeriu, Dariolli Rafael, Demin Oleg, Ellinwood, Nicholas, Fey, Dirk, Gulati Abhishek, Helikar Tomas, Jordie Eric, Musante, Cynthia, Saez-Rodriguez, Julio, Sobie, Eric
Published in Journal of pharmacokinetics and pharmacodynamics (01.02.2022)
Published in Journal of pharmacokinetics and pharmacodynamics (01.02.2022)
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Artificial Intelligence for Quantitative Modeling in Drug Discovery and Development: An Innovation and Quality Consortium Perspective on Use Cases and Best Practices
Terranova, Nadia, Renard, Didier, Shahin, Mohamed H., Menon, Sujatha, Cao, Youfang, Hop, Cornelis E.C.A., Hayes, Sean, Madrasi, Kumpal, Stodtmann, Sven, Tensfeldt, Thomas, Vaddady, Pavan, Ellinwood, Nicholas, Lu, James
Published in Clinical pharmacology and therapeutics (01.04.2024)
Published in Clinical pharmacology and therapeutics (01.04.2024)
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Two heads are better than one: current landscape of integrating QSP and machine learning: An ISoP QSP SIG white paper by the working group on the integration of quantitative systems pharmacology and machine learning
Zhang, Tongli, Androulakis, Ioannis P., Bonate, Peter, Cheng, Limei, Helikar, Tomáš, Parikh, Jaimit, Rackauckas, Christopher, Subramanian, Kalyanasundaram, Cho, Carolyn R.
Published in Journal of pharmacokinetics and pharmacodynamics (01.02.2022)
Published in Journal of pharmacokinetics and pharmacodynamics (01.02.2022)
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Sodium Homeostasis Dynamically Regulates Sinoatrial Node Pacemaker Activity
Morotti, Stefano, Rickert, Christian, St Clair, Joshua, Ellinwood, Nicholas, Proenza, Catherine, Grandi, Eleonora
Published in Biophysical journal (03.02.2017)
Published in Biophysical journal (03.02.2017)
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Effects of Modulation of Small-Conductance Calcium-Activated Potassium Current on Atrial Electrophysiology and Arrhythmogenesis: A Population-Based Computational Study
Morotti, Stefano, Ellinwood, Nicholas, Ni, Haibo, Koivumäki, Jussi T., Maleckar, Mary M., Heijman, Jordi, Dobrev, Dobromir, Grandi, Eleonora
Published in Biophysical journal (02.02.2018)
Published in Biophysical journal (02.02.2018)
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Erratum: "Revealing kinetics and state-dependent binding properties of I Kur -targeting drugs that maximize atrial fibrillation selectivity" [Chaos 27, 093918 (2017)]
Ellinwood, Nicholas, Dobrev, Dobromir, Morotti, Stefano, Grandi, Eleonora
Published in Chaos (Woodbury, N.Y.) (01.10.2017)
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Published in Chaos (Woodbury, N.Y.) (01.10.2017)
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