The Eukaryotic Proteome Is Shaped by E3 Ubiquitin Ligases Targeting C-Terminal Degrons
Koren, Itay, Timms, Richard T., Kula, Tomasz, Xu, Qikai, Li, Mamie Z., Elledge, Stephen J.
Published in Cell (14.06.2018)
Published in Cell (14.06.2018)
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The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4
Kang, Chanhee, Xu, Qikai, Martin, Timothy D., Li, Mamie Z., Demaria, Marco, Aron, Liviu, Lu, Tao, Yankner, Bruce A., Campisi, Judith, Elledge, Stephen J.
Published in Science (American Association for the Advancement of Science) (25.09.2015)
Published in Science (American Association for the Advancement of Science) (25.09.2015)
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Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response
Elia, Andrew E.H., Boardman, Alexander P., Wang, David C., Huttlin, Edward L., Everley, Robert A., Dephoure, Noah, Zhou, Chunshui, Koren, Itay, Gygi, Steven P., Elledge, Stephen J.
Published in Molecular cell (03.09.2015)
Published in Molecular cell (03.09.2015)
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Origins of lymphatic and distant metastases in human colorectal cancer
Naxerova, Kamila, Reiter, Johannes G., Brachtel, Elena, Lennerz, Jochen K., van de Wetering, Marc, Rowan, Andrew, Cai, Tianxi, Clevers, Hans, Swanton, Charles, Nowak, Martin A., Elledge, Stephen J., Jain, Rakesh K.
Published in Science (American Association for the Advancement of Science) (07.07.2017)
Published in Science (American Association for the Advancement of Science) (07.07.2017)
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Global Identification of Modular Cullin-RING Ligase Substrates
Emanuele, Michael J., Elia, Andrew E.H., Xu, Qikai, Thoma, Claudio R., Izhar, Lior, Leng, Yumei, Guo, Ailan, Chen, Yi-Ning, Rush, John, Hsu, Paul Wei-Che, Yen, Hsueh-Chi Sherry, Elledge, Stephen J.
Published in Cell (14.10.2011)
Published in Cell (14.10.2011)
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The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning
Bruno, Peter M., Lu, Mengrou, Dennis, Kady A., Inam, Haider, Moore, Connor J., Sheehe, John, Elledge, Stephen J., Hemann, Michael T., Pritchard, Justin R.
Published in Proceedings of the National Academy of Sciences - PNAS (25.02.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (25.02.2020)
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A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response
Adamson, Britt, Smogorzewska, Agata, Sigoillot, Frederic D., King, Randall W., Elledge, Stephen J.
Published in Nature cell biology (01.03.2012)
Published in Nature cell biology (01.03.2012)
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The adaptive immune system is a major driver of selection for tumor suppressor gene inactivation
Martin, Timothy D, Patel, Rupesh S, Cook, Danielle R, Choi, Mei Yuk, Patil, Ajinkya, Liang, Anthony C, Li, Mamie Z, Haigis, Kevin M, Elledge, Stephen J
Published in Science (American Association for the Advancement of Science) (17.09.2021)
Published in Science (American Association for the Advancement of Science) (17.09.2021)
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Comprehensive serological profiling of human populations using a synthetic human virome
Xu, George J., Kula, Tomasz, Xu, Qikai, Li, Mamie Z., Vernon, Suzanne D., Ndung'u, Thumbi, Ruxrungtham, Kiat, Sanchez, Jorge, Brander, Christian, Chung, Raymond T., O'Connor, Kevin C., Walker, Bruce, Larman, H. Benjamin, Elledge, Stephen J.
Published in Science (American Association for the Advancement of Science) (05.06.2015)
Published in Science (American Association for the Advancement of Science) (05.06.2015)
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Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay
Fellmann, Christof, Zuber, Johannes, McJunkin, Katherine, Chang, Kenneth, Malone, Colin D., Dickins, Ross A., Xu, Qikai, Hengartner, Michael O., Elledge, Stephen J., Hannon, Gregory J., Lowe, Scott W.
Published in Molecular cell (18.03.2011)
Published in Molecular cell (18.03.2011)
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Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns
Sack, Laura Magill, Davoli, Teresa, Li, Mamie Z., Li, Yuyang, Xu, Qikai, Naxerova, Kamila, Wooten, Eric C., Bernardi, Ronald J., Martin, Timothy D., Chen, Ting, Leng, Yumei, Liang, Anthony C., Scorsone, Kathleen A., Westbrook, Thomas F., Wong, Kwok-Kin, Elledge, Stephen J.
Published in Cell (05.04.2018)
Published in Cell (05.04.2018)
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Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress
Ciccia, Alberto, Nimonkar, Amitabh V., Hu, Yiduo, Hajdu, Ildiko, Achar, Yathish Jagadheesh, Izhar, Lior, Petit, Sarah A., Adamson, Britt, Yoon, John C., Kowalczykowski, Stephen C., Livingston, David M., Haracska, Lajos, Elledge, Stephen J.
Published in Molecular cell (10.08.2012)
Published in Molecular cell (10.08.2012)
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quantitative atlas of mitotic phosphorylation
Dephoure, Noah, Zhou, Chunshui, Villén, Judit, Beausoleil, Sean A, Bakalarski, Corey E, Elledge, Stephen J, Gygi, Steven P
Published in Proceedings of the National Academy of Sciences - PNAS (05.08.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (05.08.2008)
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A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors
Izhar, Lior, Adamson, Britt, Ciccia, Alberto, Lewis, Jedd, Pontano-Vaites, Laura, Leng, Yumei, Liang, Anthony C., Westbrook, Thomas F., Harper, J. Wade, Elledge, Stephen J.
Published in Cell reports (Cambridge) (09.06.2015)
Published in Cell reports (Cambridge) (09.06.2015)
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C-Terminal End-Directed Protein Elimination by CRL2 Ubiquitin Ligases
Lin, Hsiu-Chuan, Yeh, Chi-Wei, Chen, Yen-Fu, Lee, Ting-Ting, Hsieh, Pei-Yun, Rusnac, Domnita V., Lin, Sung-Ya, Elledge, Stephen J., Zheng, Ning, Yen, Hsueh-Chi S.
Published in Molecular cell (17.05.2018)
Published in Molecular cell (17.05.2018)
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Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen
Brass, Abraham L, Dykxhoorn, Derek M, Benita, Yair, Yan, Nan, Engelman, Alan, Xavier, Ramnik J, Lieberman, Judy, Elledge, Stephen J
Published in Science (American Association for the Advancement of Science) (15.02.2008)
Published in Science (American Association for the Advancement of Science) (15.02.2008)
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