Drug-induced perturbations of the bile acid pool, cholestasis, and hepatotoxicity: mechanistic considerations beyond the direct inhibition of the bile salt export pump
Rodrigues, A David, Lai, Yurong, Cvijic, Mary Ellen, Elkin, Lisa L, Zvyaga, Tatyana, Soars, Matthew G
Published in Drug metabolism and disposition (01.04.2014)
Published in Drug metabolism and disposition (01.04.2014)
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Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain
Tokarski, John S., Zupa-Fernandez, Adriana, Tredup, Jeffrey A., Pike, Kristen, Chang, ChiehYing, Xie, Dianlin, Cheng, Lihong, Pedicord, Donna, Muckelbauer, Jodi, Johnson, Stephen R., Wu, Sophie, Edavettal, Suzanne C., Hong, Yang, Witmer, Mark R., Elkin, Lisa L., Blat, Yuval, Pitts, William J., Weinstein, David S., Burke, James R.
Published in The Journal of biological chemistry (24.04.2015)
Published in The Journal of biological chemistry (24.04.2015)
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Application of an in vitro OAT assay in drug design and optimization of renal clearance
Soars, Matthew G., Barton, Patrick, Elkin, Lisa L., Mosure, Kathleen W., Sproston, Joanne L., Riley, Robert J.
Published in Xenobiotica (01.07.2014)
Published in Xenobiotica (01.07.2014)
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Imidazo[1,2-a]pyrazine diaryl ureas: Inhibitors of the receptor tyrosine kinase EphB4
Mitchell, Scott A., Danca, Mihaela Diana, Blomgren, Peter A., Darrow, James W., Currie, Kevin S., Kropf, Jeffrey E., Lee, Seung H., Gallion, Steven L., Xiong, Jin-Ming, Pippin, Douglas A., DeSimone, Robert W., Brittelli, David R., Eustice, David C., Bourret, Aaron, Hill-Drzewi, Melissa, Maciejewski, Patricia M., Elkin, Lisa L.
Published in Bioorganic & medicinal chemistry letters (15.12.2009)
Published in Bioorganic & medicinal chemistry letters (15.12.2009)
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Inhibitor Scaffolds as New Allele Specific Kinase Substrates
Kraybill, Brian C, Elkin, Lisa L, Blethrow, Justin D, Morgan, David O, Shokat, Kevan M
Published in Journal of the American Chemical Society (16.10.2002)
Published in Journal of the American Chemical Society (16.10.2002)
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