Drug screening for human genetic diseases using iPSC models
Elitt, Matthew S, Barbar, Lilianne, Tesar, Paul J
Published in Human molecular genetics (01.08.2018)
Published in Human molecular genetics (01.08.2018)
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Journal Article
Rapid functional genetics of the oligodendrocyte lineage using pluripotent stem cells
Lager, Angela M, Corradin, Olivia G, Cregg, Jared M, Elitt, Matthew S, Shick, H Elizabeth, Clayton, Benjamin L L, Allan, Kevin C, Olsen, Hannah E, Madhavan, Mayur, Tesar, Paul J
Published in Nature communications (13.09.2018)
Published in Nature communications (13.09.2018)
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Journal Article
Geminin promotes neural fate acquisition of embryonic stem cells by maintaining chromatin in an accessible and hyperacetylated state
Yellajoshyula, Dhananjay, Patterson, Ethan S, Elitt, Matthew S, Kroll, Kristen L
Published in Proceedings of the National Academy of Sciences - PNAS (22.02.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (22.02.2011)
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Journal Article
Chemical Screening Identifies Enhancers of Mutant Oligodendrocyte Survival and Unmasks a Distinct Pathological Phase in Pelizaeus-Merzbacher Disease
Elitt, Matthew S., Shick, H. Elizabeth, Madhavan, Mayur, Allan, Kevin C., Clayton, Benjamin L.L., Weng, Chen, Miller, Tyler E., Factor, Daniel C., Barbar, Lilianne, Nawash, Baraa S., Nevin, Zachary S., Lager, Angela M., Li, Yan, Jin, Fulai, Adams, Drew J., Tesar, Paul J.
Published in Stem cell reports (11.09.2018)
Published in Stem cell reports (11.09.2018)
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Journal Article
Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination
Hubler, Zita, Allimuthu, Dharmaraja, Bederman, Ilya, Elitt, Matthew S, Madhavan, Mayur, Allan, Kevin C, Shick, H Elizabeth, Garrison, Eric, T Karl, Molly, Factor, Daniel C, Nevin, Zachary S, Sax, Joel L, Thompson, Matthew A, Fedorov, Yuriy, Jin, Jing, Wilson, William K, Giera, Martin, Bracher, Franz, Miller, Robert H, Tesar, Paul J, Adams, Drew J
Published in Nature (London) (01.08.2018)
Published in Nature (London) (01.08.2018)
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Journal Article
Suppression of proteolipid protein rescues Pelizaeus-Merzbacher disease
Elitt, Matthew S, Barbar, Lilianne, Shick, H Elizabeth, Powers, Berit E, Maeno-Hikichi, Yuka, Madhavan, Mayur, Allan, Kevin C, Nawash, Baraa S, Gevorgyan, Artur S, Hung, Stevephen, Nevin, Zachary S, Olsen, Hannah E, Hitomi, Midori, Schlatzer, Daniela M, Zhao, Hien T, Swayze, Adam, LePage, David F, Jiang, Weihong, Conlon, Ronald A, Rigo, Frank, Tesar, Paul J
Published in Nature (London) (17.09.2020)
Published in Nature (London) (17.09.2020)
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Journal Article
Enhancers of Human and Rodent Oligodendrocyte Formation Predominantly Induce Cholesterol Precursor Accumulation
Sax, Joel L., Hershman, Samantha N., Hubler, Zita, Allimuthu, Dharmaraja, Elitt, Matthew S., Bederman, Ilya, Adams, Drew J.
Published in ACS chemical biology (19.08.2022)
Published in ACS chemical biology (19.08.2022)
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Journal Article
Cellular Maturation of Oligodendrocytes is Governed by Transient Gene Melting
Allan, Kevin C, Miller, Tyler E, Morton, Andrew R, Scavuzzo, Marissa A, Elitt, Matthew S, Clayton, Benjamin Ll, Hu, Lucille R, Vrabic, Jost K, Olsen, Hannah E, Factor, Daniel C, Henninger, Jonathan E, Young, Richard A, Lin, Charles Y, Scacheri, Peter C, Tesar, Paul J
Published in bioRxiv (18.11.2022)
Published in bioRxiv (18.11.2022)
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Paper
Therapeutic suppression of proteolipid protein rescues Pelizaeus-Merzbacher Disease in mice
Elitt, Matthew S, Barbar, Lilianne, Shick, H Elizabeth, Powers, Berit E, Maeno-Hikitchi, Yuka, Madhavan, Mayur, Allan, Kevin C, Nawash, Baraa S, Nevin, Zachary S, Olsen, Hannah E, Hitomi, Midori, Lepage, David F, Jiang, Weihong, Conlon, Ronald A, Rigo, Frank, Tesar, Paul J
Published in bioRxiv (31.12.2018)
Published in bioRxiv (31.12.2018)
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Paper
Compounds and methods for promoting myelination
HUBLER ZITA, ADAMS DARREN, ELITT MATTHEW, ALIMUTHU, DINESH, TESAR PAUL
Year of Publication 24.06.2022
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Year of Publication 24.06.2022
Patent
COMPOUNDS AND METHODS OF PROMOTING MYELINATION
ALLIMUTHU DHARMARAJA, HUBLER ZITA, ADAMS DREW, ELITT MATTHEW, TESAR PAUL
Year of Publication 21.05.2019
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Year of Publication 21.05.2019
Patent