The efficacy of the ribonucleotide reductase inhibitor Didox in preclinical models of AML
Cook, Guerry J, Caudell, David L, Elford, Howard L, Pardee, Timothy S
Published in PloS one (17.11.2014)
Published in PloS one (17.11.2014)
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Compromised axon initial segment integrity in EAE is preceded by microglial reactivity and contact
Clark, Kareem C., Josephson, Anna, Benusa, Savannah D., Hartley, Rebecca K., Baer, Matthew, Thummala, Suneel, Joslyn, Martha, Sword, Brooke A., Elford, Howard, Oh, Unsong, Dilsizoglu-Senol, Aysegul, Lubetzki, Catherine, Davenne, Marc, DeVries, George H., Dupree, Jeffrey L.
Published in Glia (01.07.2016)
Published in Glia (01.07.2016)
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Gallic acid inhibits ribonucleotide reductase and cyclooxygenases in human HL-60 promyelocytic leukemia cells
Madlener, Sibylle, Illmer, Christoph, Horvath, Zsuzsanna, Saiko, Philipp, Losert, Annemarie, Herbacek, Irene, Grusch, Michael, Elford, Howard L, Krupitza, Georg, Bernhaus, Astrid, Fritzer-Szekeres, Monika, Szekeres, Thomas
Published in Cancer letters (08.01.2007)
Published in Cancer letters (08.01.2007)
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Didox (3,4-dihydroxybenzohydroxamic acid) reduces the vascular inflammation induced by acute intravascular hemolysis
Silva, Juliete A.F., Gotardo, Érica M.F., Chweih, Hanan, Miguel, Lediana I., Ferreira, Wilson A., Hedlund, Bo, Elford, Howard L., Leonardo, Flavia C., Costa, Fernando F., Conran, Nicola
Published in Blood cells, molecules, & diseases (01.03.2020)
Published in Blood cells, molecules, & diseases (01.03.2020)
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Didox (3,4-dihydroxybenzohydroxamic acid) suppresses IL-33-induced cytokine production in primary mouse mast cells
Caslin, Heather L., McLeod, Jamie Josephine Avila, Spence, Andrew J., Qayum, Amina Abdul, Kolawole, Elizabeth Motunrayo, Taruselli, Marcela T., Paranjape, Anuya, Elford, Howard L., Ryan, John J.
Published in Cellular immunology (01.09.2017)
Published in Cellular immunology (01.09.2017)
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Didox (3,4-dihydroxybenzohydroxamic acid) suppresses IgE-mediated mast cell activation through attenuation of NFκB and AP-1 transcription
McLeod, Jamie Josephine Avila, Caslin, Heather L., Spence, Andrew J., Kolawole, Elizabeth M., Qayum, Amina Abdul, Paranjape, Anuya, Taruselli, Marcela, Haque, Tamara T., Kiwanuka, Kasalina N., Elford, Howard L., Ryan, John J.
Published in Cellular immunology (01.12.2017)
Published in Cellular immunology (01.12.2017)
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Inhibition of allogeneic inflammatory responses by the Ribonucleotide Reductase Inhibitors, Didox and Trimidox
Inayat, Mohammed S, El-Amouri, Ismail S, Bani-Ahmad, Mohammad, Elford, Howard L, Gallicchio, Vincent S, Oakley, Oliver R
Published in Journal of inflammation (London, England) (18.08.2010)
Published in Journal of inflammation (London, England) (18.08.2010)
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Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance
Månsson, Emma, Flordal, Emma, Liliemark, Jan, Spasokoukotskaja, Tatiana, Elford, Howard, Lagercrantz, Svetlana, Eriksson, Staffan, Albertioni, Freidoun
Published in Biochemical pharmacology (15.01.2003)
Published in Biochemical pharmacology (15.01.2003)
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Paradoxical response to prophylactic Didox (N-3, 4 trihydroxybenzamide) treatment in murine cytomegalovirus-infected mice
GO, Vera, TANG-FELDMAN, Yajarayma J, LOCHHEAD, Stephanie R, LOCHHEAD, G. Raymond, YU, Cindy Q, ELFORD, Howard L, INAYAT, Mohammed S, OAKLEY, Oliver R, POMEROY, Claire
Published in Antiviral therapy (01.01.2011)
Published in Antiviral therapy (01.01.2011)
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Didox (A Novel Ribonucleotide Reductase Inhibitor) Overcomes bcl-2 Mediated Radiation Resistance in Prostate Cancer Cell Line PC-3
Inayat, Mohammed S., Chendil, Damodaran, Mohiuddin, Mohammed, Elford, Howard L., Gallicchio, Vincent S., Ahmed, Mansoor M.
Published in Cancer biology & therapy (01.09.2002)
Published in Cancer biology & therapy (01.09.2002)
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Oxygen carriers: A selected review
Inayat, Mohammed S., Bernard, Andrew C., Gallicchio, Vincent S., Garvy, Beth A., Elford, Howard L., Oakley, Oliver R.
Published in Transfusion and apheresis science (01.02.2006)
Published in Transfusion and apheresis science (01.02.2006)
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Synergistic cytotoxicity of the ribonucleotide reductase inhibitor didox (3,4-dihydroxy-benzohydroxamic acid) and the alkylating agent carmustine (BCNU) in 9L rat gliosarcoma cells and DAOY human medulloblastoma cells
HORVATH, Zsuzsanna, HÖCHTL, Thomas, BAUER, Wolfgang, FRITZER-SZEKERES, Monika, ELFORD, Howard L, SZEKERES, Thomas, TIHAN, Tarik
Published in Cancer chemotherapy and pharmacology (01.08.2004)
Published in Cancer chemotherapy and pharmacology (01.08.2004)
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Trimidox, an inhibitor of ribonucleotide reductase, synergistically enhances the inhibition of colony formation by Ara-C in HL-60 human promyelocytic leukemia cells
Fritzer-Szekeres, Monika, Salamon, Alexandra, Grusch, Michael, Horvath, Zsuzsanna, Höchtl, Thomas, Steinbrugger, Richard, Jäger, Walter, Krupitza, Georg, Elford, Howard L, Szekeres, Thomas
Published in Biochemical pharmacology (01.08.2002)
Published in Biochemical pharmacology (01.08.2002)
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Combination of inhibitors of lymphocyte activation (hydroxyurea, trimidox, and didox) and reverse transcriptase (didanosine) suppresses development of murine retrovirus-induced lymphoproliferative disease
Mayhew, Christopher N., Sumpter, Ryan, Inayat, Mohammed, Cibull, Michael, Phillips, Jonathan D., Elford, Howard L., Gallicchio, Vincent S.
Published in Antiviral research (2005)
Published in Antiviral research (2005)
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