Phosphoinositide 3-kinase γ/δ inhibition limits infarct size after myocardial ischemia/reperfusion injury
Doukas, John, Wrasidlo, Wolfgang, Noronha, Glenn, Dneprovskaia, Elena, Fine, Richard, Weis, Sara, Hood, John, DeMaria, Anthony, Soll, Richard, Cheresh, David
Published in Proceedings of the National Academy of Sciences - PNAS (26.12.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (26.12.2006)
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Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRβ/B-RAF
Murphy, Eric A, Shields, David J, Stoletov, Konstantin, Dneprovskaia, Elena, McElroy, Michele, Greenberg, Joshua I, Lindquist, Jeff, Acevedo, Lisette M, Anand, Sudarshan, Majeti, Bharat Kumar, Tsigelny, Igor, Saldanha, Adrian, Walsh, Breda, Hoffman, Robert M, Bouvet, Michael, Klemke, Richard L, Vogt, Peter K, Arnold, Lee, Wrasidlo, Wolfgang, Cheresh, David A
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Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2010)
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Inhibitors of ABL and the ABL-T315I mutation
Noronha, Glenn, Cao, Jianguo, Chow, Chun P, Dneprovskaia, Elena, Fine, Richard M, Hood, John, Kang, Xinshan, Klebansky, Boris, Lohse, Dan, Mak, Chi Ching, McPherson, Andre, Palanki, Moorthy S S, Pathak, Ved P, Renick, Joel, Soll, Richard, Zeng, Binqi
Published in Current topics in medicinal chemistry (01.07.2008)
Published in Current topics in medicinal chemistry (01.07.2008)
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Synthesis of a model system for the preparation of phloroglucinol containing natural products
Kraus, George A, Dneprovskaia, Elena, Nguyen, Tuan H, Jeon, Insik
Published in Tetrahedron (03.11.2003)
Published in Tetrahedron (03.11.2003)
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Discovery and preliminary structure–activity relationship studies of novel benzotriazine based compounds as Src inhibitors
Noronha, Glenn, Barrett, Kathy, Cao, Jianguo, Dneprovskaia, Elena, Fine, Richard, Gong, Xianchang, Gritzen, Colleen, Hood, John, Kang, Xinshan, Klebansky, Boris, Li, G., Liao, W., Lohse, Dan, Mak, Chi Ching, McPherson, Andrew, Palanki, Moorthy S.S., Pathak, Ved P., Renick, Joel, Soll, Richard, Splittgerber, Ute, Wrasidlo, Wolfgang, Zeng, Binqi, Zhao, Ningning, Zhou, Y.
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
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Aerosolized phosphoinositide 3-kinase gamma/delta inhibitor TG100-115 [3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol] as a therapeutic candidate for asthma and chronic obstructive pulmonary disease
Doukas, John, Eide, Lisa, Stebbins, Karin, Racanelli-Layton, Adrienne, Dellamary, Luis, Martin, Michael, Dneprovskaia, Elena, Noronha, Glenn, Soll, Richard, Wrasidlo, Wolfgang, Acevedo, Lisette M, Cheresh, David A
Published in The Journal of pharmacology and experimental therapeutics (01.03.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2009)
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Discovery of 3,3‘-(2,4-Diaminopteridine-6,7-diyl)diphenol as an Isozyme-Selective Inhibitor of PI3K for the Treatment of Ischemia Reperfusion Injury Associated with Myocardial Infarction
Palanki, Moorthy S. S, Dneprovskaia, Elena, Doukas, John, Fine, Richard M, Hood, John, Kang, Xinshan, Lohse, Dan, Martin, Michael, Noronha, Glenn, Soll, Richard M, Wrasidlo, Wolfgang, Yee, Shiyin, Zhu, Hong
Published in Journal of medicinal chemistry (06.09.2007)
Published in Journal of medicinal chemistry (06.09.2007)
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Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine—a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays
Noronha, Glenn, Barrett, Kathy, Boccia, Antonio, Brodhag, Tessa, Cao, Jianguo, Chow, Chun P., Dneprovskaia, Elena, Doukas, John, Fine, Richard, Gong, Xianchang, Gritzen, Colleen, Gu, Hong, Hanna, Ehab, Hood, John D., Hu, Steven, Kang, Xinshan, Key, Jann, Klebansky, Boris, Kousba, Ahmed, Li, Ge, Lohse, Dan, Mak, Chi Ching, McPherson, Andrew, Palanki, Moorthy S.S., Pathak, Ved P., Renick, Joel, Shi, Feng, Soll, Richard, Splittgerber, Ute, Stoughton, Silva, Tang, Suhan, Yee, Shiyin, Zeng, Binqi, Zhao, Ningning, Zhu, Hong
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
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Aerosolized Phosphoinositide 3-Kinase γ/δ Inhibitor TG100-115 [3-[2,4-Diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol] as a Therapeutic Candidate for Asthma and Chronic Obstructive Pulmonary Disease
John Doukas, Lisa Eide, Karin Stebbins, Adrienne Racanelli-Layton, Luis Dellamary, Michael Martin, Elena Dneprovskaia, Glenn Noronha, Richard Soll, Wolfgang Wrasidlo, Lisette M. Acevedo, David A. Cheresh
Published in The Journal of pharmacology and experimental therapeutics (01.03.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2009)
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Journal Article
Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFR[beta]/B-RAF
Murphy, Eric A, Shields, David J, Stoletov, Konstantin, Dneprovskaia, Elena, McElroy, Michele, Greenberg, Joshua I, Lindquist, Jeff, Acevedo, Lisette M, Anand, Sudarshan, Majeti, Bharat Kumar, Tsigelny, Igor, Saldanha, Adrian, Walsh, Breda, Hoffman, Robert M, Bouvet, Michael, Klemke, Richard L, Vogt, Peter K, Arnold, Lee, Wrasidlo, Wolfgang, Cheresh, David A
Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2010)
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Published in Proceedings of the National Academy of Sciences - PNAS (02.03.2010)
Journal Article
Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRβ/B-RAF
Murphy, Eric A, Shields, David J, Stoletov, Konstantin, Dneprovskaia, Elena, McElroy, Michele, Greenberg, Joshua I, Lindquist, Jeff, Acevedo, Lisette M, Anand, Sudarshan, Majeti, Bharat Kumar, Tsigelny, Igor, Saldanha, Adrian, Walsh, Breda, Hoffman, Robert M, Bouvet, Michael, Klemke, Richard L, Vogt, Peter K, Arnold, Lee, Wrasidlo, Wolfgang, Cheresh, David A
Published in Proceedings of the National Academy of Sciences - PNAS (2010)
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Published in Proceedings of the National Academy of Sciences - PNAS (2010)
Journal Article
Development of novel benzotriazines for drug discovery
Palanki, Moorthy Ss, Cao, Jianguo, Chow, Chun P, Dneprovskaia, Elena, Mak, Chi Ching, McPherson, Andrew, Pathak, Ved P, Renick, Joel, Soll, Richard, Zeng, Binqi, Noronha, Glenn
Published in Expert opinion on drug discovery (01.01.2009)
Published in Expert opinion on drug discovery (01.01.2009)
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