Novel promising benzoxazole/benzothiazole‐derived immunomodulatory agents: Design, synthesis, anticancer evaluation, and in silico ADMET analysis
Elkady, Hazem, El‐Adl, Khaled, Sakr, Helmy, Abdelraheem, Adel S., Eissa, Sally I., El‐Zahabi, Mohamed Ayman
Published in Archiv der Pharmazie (Weinheim) (01.09.2023)
Published in Archiv der Pharmazie (Weinheim) (01.09.2023)
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Design, synthesis, in silico studies, and biological evaluation of novel pyrimidine-5-carbonitrile derivatives as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers
Saleh, Abdulrahman M, Mahdy, Hazem A, El-Zahabi, Mohamed Ayman, Mehany, Ahmed B M, Khalifa, Mohamed M, Eissa, Ibrahim H
Published in RSC advances (19.07.2023)
Published in RSC advances (19.07.2023)
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Design, synthesis, anticancer evaluation, and in silico ADMET analysis of novel thalidomide analogs as promising immunomodulatory agents
Kotb, Anas Ramadan, Abdallah, Abdallah E, Elkady, Hazem, Eissa, Ibrahim H, Taghour, Mohammed S, Bakhotmah, Dina Abed, Abdelghany, Tamer M, El-Zahabi, Mohamed Ayman
Published in RSC advances (03.04.2023)
Published in RSC advances (03.04.2023)
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Synthesis, biological evaluation, and molecular docking of new series of antitumor and apoptosis inducers designed as VEGFR-2 inhibitors
Abdallah, Abdallah E., Mabrouk, Reda R., Al Ward, Maged Mohammed Saleh, Eissa, Sally I., Elkaeed, Eslam B., Mehany, Ahmed B. M., Abo-Saif, Mariam A., El-Feky, Ola A., Alesawy, Mohamed S., El-Zahabi, Mohamed Ayman
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
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Discovery of New VEGFR-2 Inhibitors: Design, Synthesis, Anti-Proliferative Evaluation, Docking, and MD Simulation Studies
Elkaeed, Eslam B, Yousef, Reda G, Khalifa, Mohamed M, Ibrahim, Albaraa, Mehany, Ahmed B. M, Gobaara, Ibraheem M. M, Alsfouk, Bshra A, Eldehna, Wagdy M, Metwaly, Ahmed M, Eissa, Ibrahim H, El-Zahabi, Mohamed Ayman
Published in Molecules (Basel, Switzerland) (21.09.2022)
Published in Molecules (Basel, Switzerland) (21.09.2022)
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Design, Synthesis, Molecular Modeling and Anti-Hyperglycemic Evaluation of Quinazoline-Sulfonylurea Hybrids as Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Sulfonylurea Receptor (SUR) Agonists
El-Zahabi, Mohamed Ayman, Bamanie, Faida H., Ghareeb, Salah, Alshaeri, Heba K., Alasmari, Moudi M., Moustafa, Mohamed, Al-Marzooki, Zohair, Zayed, Mohamed F.
Published in International journal of molecular sciences (01.09.2022)
Published in International journal of molecular sciences (01.09.2022)
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Design, Synthesis, and Biological Evaluation of New Potential Unusual Modified Anticancer Immunomodulators for Possible Non-Teratogenic Quinazoline-Based Thalidomide Analogs
Mabrouk, Reda R, Abdallah, Abdallah E, Mahdy, Hazem A, El-Kalyoubi, Samar A, Kamal, Omar Jamal, Abdelghany, Tamer M, Zayed, Mohamed F, Alshaeri, Heba K, Alasmari, Moudi M, El-Zahabi, Mohamed Ayman
Published in International journal of molecular sciences (01.08.2023)
Published in International journal of molecular sciences (01.08.2023)
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Journal Article
Design, synthesis, and biological evaluation of new challenging thalidomide analogs as potential anticancer immunomodulatory agents
El-Zahabi, Mohamed Ayman, Sakr, Helmy, El-Adl, Khaled, Zayed, Mohamed, Abdelraheem, Adel S., Eissa, Sally I., Elkady, Hazem, Eissa, Ibrahim H.
Published in Bioorganic chemistry (01.11.2020)
Published in Bioorganic chemistry (01.11.2020)
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Journal Article
Immunomodulatory quinazoline-based thalidomide analogs: Design, synthesis, apoptosis and anticancer evaluations
Abdallah, Abdallah E., Eissa, Ibrahim H., Mehany, Ahmed B.M., Sakr, Helmy, Atwa, Ahmed, El-Adl, Khaled, El-Zahabi, Mohamed Ayman
Published in Journal of molecular structure (05.06.2023)
Published in Journal of molecular structure (05.06.2023)
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Design, synthesis, anticancer evaluation, in silico docking and ADMET analysis of novel indole-based thalidomide analogs as promising immunomodulatory agents
El-Zahabi, Mohamed Ayman, Elkady, Hazem, Sakr, Helmy, Abdelraheem, Adel S., Eissa, Sally I., El-Adl, Khaled
Published in Journal of biomolecular structure & dynamics (29.12.2023)
Published in Journal of biomolecular structure & dynamics (29.12.2023)
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Design, synthesis and biological evaluation of newly triazolo-quinoxaline based potential immunomodulatory anticancer molecules
Ward, Maged Mohammed Saleh Al, Abdallah, Abdallah E., Zayed, Mohamed F., Ayyad, Rezk R., El-Zahabi, Mohamed Ayman
Published in Journal of molecular structure (15.02.2024)
Published in Journal of molecular structure (15.02.2024)
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Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of phthalimide-sulfonylurea hybrids as PPARγ and SUR agonists
El-Zahabi, Mohamed Ayman, Elbendary, Eman R., Bamanie, Faida H., Radwan, Mohamed F., Ghareib, Salah A., Eissa, Ibrahim H.
Published in Bioorganic chemistry (01.10.2019)
Published in Bioorganic chemistry (01.10.2019)
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Journal Article
Immunomodulation and anticancer evaluation of quinazoline-based thalidomide analogs: Design, synthesis, docking, and dynamic simulation
Abdallah, Abdallah E., Eissa, Ibrahim H., Mehany, Ahmed B.M., Sakr, Helmy, Sakr, Tamer M, Metwaly, K.H., Celik, Ismail, El-Adl, Khaled, El-Zahabi, Mohamed Ayman
Published in Journal of molecular structure (05.12.2024)
Published in Journal of molecular structure (05.12.2024)
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Biological and computational assessment of new synthesized nicotinamides as potential immunomodulatory VEGFR-2 inhibitors
Yousef, Reda G., Elwan, Alaa, Abdallah, Abdallah E., Elkady, Hazem, Mehany, Ahmed B.M., Abo-Saif, Mariam Ali, Radwan, Mohamed M., ElSohly, Mahmoud A., Ibrahim, Ibrahim M., Elkady, Mohamed A., El-Zahabi, Mohamed Ayman, Eissa, Ibrahim H.
Published in Journal of molecular structure (05.06.2024)
Published in Journal of molecular structure (05.06.2024)
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Journal Article
Design, synthesis and molecular modeling of new quinazolin-4(3H)-one based VEGFR-2 kinase inhibitors for potential anticancer evaluation
Abdallah, Abdallah E., Eissa, Sally I., Al Ward, Maged Mohammed Saleh, Mabrouk, Reda R., Mehany, Ahmed B.M., El-Zahabi, Mohamed Ayman
Published in Bioorganic chemistry (01.04.2021)
Published in Bioorganic chemistry (01.04.2021)
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Journal Article
Design, synthesis, studies, and biological evaluation of novel pyrimidine-5-carbonitrile derivatives as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers
Saleh, Abdulrahman M, Mahdy, Hazem A, El-Zahabi, Mohamed Ayman, Mehany, Ahmed B. M, Khalifa, Mohamed M, Eissa, Ibrahim H
Published in RSC advances (24.07.2023)
Published in RSC advances (24.07.2023)
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Journal Article
New nicotinamide derivatives as potential anticancer agents targeting VEGFR-2: design, synthesis, in vitro , and in silico studies
Yousef, Reda G, Eissa, Ibrahim H, Elkady, Hazem, Eldehna, Wagdy M, Mehany, Ahmed B M, Nabeeh, Ahmed, Ibrahim, Ibrahim M, Elwan, Alaa, El-Zahabi, Mohamed Ayman
Published in Journal of biomolecular structure & dynamics (15.12.2023)
Published in Journal of biomolecular structure & dynamics (15.12.2023)
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Journal Article
Design, synthesis, anticancer evaluation, and ADMET analysis of novel thalidomide analogs as promising immunomodulatory agents
Kotb, Anas Ramadan, Abdallah, Abdallah E, Elkady, Hazem, Eissa, Ibrahim H, Taghour, Mohammed S, Bakhotmah, Dina Abed, Abdelghany, Tamer M, El-Zahabi, Mohamed Ayman
Published in RSC advances (03.04.2023)
Published in RSC advances (03.04.2023)
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Journal Article