One-Pot Synthesis of 1-Thia-4-azaspiro[4.4/5]alkan-3-ones via Schiff Base: Design, Synthesis, and Apoptotic Antiproliferative Properties of Dual EGFR/BRAFV600E Inhibitors
Al-Wahaibi, Lamya H., El-Sheref, Essmat M., Hammouda, Mohamed M., Youssif, Bahaa G. M.
Published in Pharmaceuticals (Basel, Switzerland) (22.03.2023)
Published in Pharmaceuticals (Basel, Switzerland) (22.03.2023)
Get full text
Journal Article
Synthesis, Antioxidant and Antiproliferative Actions of 4-(1,2,3-Triazol-1-yl)quinolin-2(1H)-ones as Multi-Target Inhibitors
El-Sheref, Essmat M., Bräse, Stefan, Tawfeek, Hendawy N., Alasmary, Fatmah Ali, Youssif, Bahaa G. M.
Published in International journal of molecular sciences (01.09.2023)
Published in International journal of molecular sciences (01.09.2023)
Get full text
Journal Article
Design, Synthesis, Molecular Docking, Antiapoptotic and Caspase-3 Inhibition of New 1,2,3-Triazole/ Bis -2(1 H )-Quinolinone Hybrids
El-Sheref, Essmat M, Aly, Ashraf A, Alshammari, Mohammed B, Brown, Alan B, Abdel-Hafez, Sara Mohamed Naguib, Abdelzaher, Walaa Yehia, Bräse, Stefan, Abdelhafez, ElShimaa M N
Published in Molecules (Basel, Switzerland) (30.10.2020)
Published in Molecules (Basel, Switzerland) (30.10.2020)
Get full text
Journal Article
Design and Synthesis of (2-oxo-1,2-Dihydroquinolin-4-yl)-1,2,3-triazole Derivatives via Click Reaction: Potential Apoptotic Antiproliferative Agents
El-Sheref, Essmat M., Elbastawesy, Mohammed A. I., Brown, Alan B., Shawky, Ahmed M., Gomaa, Hesham A. M., Bräse, Stefan, Youssif, Bahaa G. M.
Published in Molecules (Basel, Switzerland) (10.11.2021)
Published in Molecules (Basel, Switzerland) (10.11.2021)
Get full text
Journal Article
Synthesis of novel 1,2-bis-quinolinyl-1,4-naphthoquinones: ERK2 inhibition, cytotoxicity and molecular docking studies
Aly, Ashraf A., El-Sheref, Essmat M., Bakheet, Momtaz E.M., Mourad, Mai A.E., Brown, Alan B., Bräse, Stefan, Nieger, Martin, Ibrahim, Mahmoud A.A.
Published in Bioorganic chemistry (01.12.2018)
Published in Bioorganic chemistry (01.12.2018)
Get full text
Journal Article
Design, Synthesis and Biological Evaluation of Syn and Anti -like Double Warhead Quinolinones Bearing Dihydroxy Naphthalene Moiety as Epidermal Growth Factor Receptor Inhibitors with Potential Apoptotic Antiproliferative Action
El-Sheref, Essmat M, Ameen, Mohamed A, El-Shaieb, Kamal M, Abdel-Latif, Fathy F, Abdel-Naser, Asmaa I, Brown, Alan B, Bräse, Stefan, Fathy, Hazem M, Ahmad, Iqrar, Patel, Harun, Gomaa, Hesham A M, Youssif, Bahaa G M, Mohamed, Asmaa H
Published in Molecules (Basel, Switzerland) (10.12.2022)
Published in Molecules (Basel, Switzerland) (10.12.2022)
Get full text
Journal Article
Synthesis and Structure Determination of Substituted Thiazole Derivatives as EGFR/BRAFV600E Dual Inhibitors Endowed with Antiproliferative Activity
Al-Wahaibi, Lamya H., El-Sheref, Essmat M., Hassan, Alaa A., Bräse, S., Nieger, M., Youssif, Bahaa G. M., Ibrahim, Mahmoud A. A., Tawfeek, Hendawy N.
Published in Pharmaceuticals (Basel, Switzerland) (17.07.2023)
Published in Pharmaceuticals (Basel, Switzerland) (17.07.2023)
Get full text
Journal Article
Synthesis of novel amidines via one-pot three component reactions: Selective topoisomerase I inhibitors with antiproliferative properties
El-Sheref, Essmat M., Tawfeek, Hendawy N., Hassan, Alaa A., Bräse, S., Elbastawesy, Mohammed A. I., Gomaa, Hesham A. M., Mostafa, Yaser A., Youssif, Bahaa G. M.
Published in Frontiers in chemistry (18.11.2022)
Published in Frontiers in chemistry (18.11.2022)
Get full text
Journal Article
A Facile Synthesis of Oxoindenothiazine and Dioxospiro(indene-2,4′-thiazine) Derivatives from (Substituted ethylidene)hydrazinecarbothioamides
Hassan, Alaa A., Ibrahim, Yusria R., El-Sheref, Essmat M., Ibrahim, Mahmoud A. A., Bräse, Stefan
Published in Journal of heterocyclic chemistry (01.07.2015)
Published in Journal of heterocyclic chemistry (01.07.2015)
Get full text
Journal Article
Novel Synthesis of Oxothiazolidine Derivatives
Hassan, Alaa A., Ibrahim, Yusria R., El-Sheref, Essmat M., Brown, Alan B.
Published in Journal of heterocyclic chemistry (01.09.2012)
Published in Journal of heterocyclic chemistry (01.09.2012)
Get full text
Journal Article
Novel Synthesis of Pyrazolyloxothiazolidine Derivatives
Hassan, Alaa A., Ibrahim, Yusria R., El-Sheref, Essmat M., Aly, Ashraf A., Bräse, Stefan, Brown, Alan B.
Published in Journal of heterocyclic chemistry (01.11.2012)
Published in Journal of heterocyclic chemistry (01.11.2012)
Get full text
Journal Article
Convenient synthesis and X-ray determination of 2-amino-6H-1,3,4-thiadiazin-3-ium bromides endowed with antiproliferative activity
Tawfeek, Hendawy N, Abdelmoez, Alshaimaa, Dahlous, Kholood A, Youssif, Bahaa G M, Bräse, Stefan, Rissanen, Kari, Nieger, Martin, El-Sheref, Essmat M
Published in RSC advances (28.05.2024)
Published in RSC advances (28.05.2024)
Get full text
Journal Article
Synthesis of potentially new schiff bases of N-substituted-2-quinolonylacetohydrazides as anti-COVID-19 agents
Alshammari, Mohammed B., Ramadan, Mohamed, Aly, Ashraf A., El-Sheref, Essmat M., Bakht, Md Afroz, Ibrahim, Mahmoud A.A., Shawky, Ahmed M.
Published in Journal of molecular structure (15.04.2021)
Published in Journal of molecular structure (15.04.2021)
Get full text
Journal Article