Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors
Salem, Ibrahim M., Mostafa, Samia M., Salama, Ismail, El-Sabbagh, Osama I., Hegazy, Wael A. H., Ibrahim, Tarek S.
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2023)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2023)
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Synthesis and antiviral activity of new pyrazole and thiazole derivatives
El-Sabbagh, Osama I., Baraka, Mohamed M., Ibrahim, Samy M., Pannecouque, Christophe, Andrei, Graciela, Snoeck, Robert, Balzarini, Jan, Rashad, Adel A.
Published in European journal of medicinal chemistry (01.09.2009)
Published in European journal of medicinal chemistry (01.09.2009)
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The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme
Malebari, Azizah M., Ibrahim, Tarek S., Salem, Ibrahim M., Salama, Ismail, Khayyat, Ahdab N., Mostafa, Samia M., El-Sabbagh, Osama I., Darwish, Khaled M.
Published in Pharmaceuticals (Basel, Switzerland) (18.09.2020)
Published in Pharmaceuticals (Basel, Switzerland) (18.09.2020)
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New thiopyridine complexes: design, electrochemical preparation and biological assessment
El-Sabbagh, Osama I., Yamany, Yamany B., Eldeab, Hany A.
Published in Polish journal of chemical technology (01.12.2019)
Published in Polish journal of chemical technology (01.12.2019)
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Synthesis of new multitarget-directed ligands containing thienopyrimidine nucleus for inhibition of 15-lipoxygenase, cyclooxygenases, and pro-inflammatory cytokines
Abdelkhalek, Ahmed S., Kothayer, Hend, Rezq, Samar, Orabi, Khaled Y., Romero, Damian G., El-Sabbagh, Osama I.
Published in European journal of medicinal chemistry (05.08.2023)
Published in European journal of medicinal chemistry (05.08.2023)
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Human dihydrofolate reductase inhibition effect of 1-Phenylpyrazolo[3,4–d]pyrimidines: Synthesis, antitumor evaluation and molecular modeling study
Salem, Ibrahim M., Mostafa, Samia M., Salama, Ismail, El-Sabbagh, Osama I., A. H. Hegazy, Wael, Ibrahim, Tarek S.
Published in Bioorganic chemistry (01.12.2022)
Published in Bioorganic chemistry (01.12.2022)
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Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold
Ibrahim, Tarek S., Salem, Ibrahim M., Mostafa, Samia M., El-Sabbagh, Osama I., ElKhamisi, Mohamed K.M., Hegazy, Lamees, Elgendy, Bahaa
Published in Bioorganic chemistry (01.07.2020)
Published in Bioorganic chemistry (01.07.2020)
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Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides
Kothayer, Hend, Elshanawani, Abdalla A., Abu Kull, Mansour E., El-Sabbagh, Osama I., Shekhar, Malathy P.V., Brancale, Andrea, Jones, Arwyn T., Westwell, Andrew D.
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
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Optimised synthesis of diamino-triazinylmethyl benzoates as inhibitors of Rad6B ubiquitin conjugating enzyme
Kothayer, Hend, Morelli, Matteo, Brahemi, Ghali, Elshanawani, Abdalla A., Abu Kull, Mansour E., El-Sabbagh, Osama I., Shekhar, Malathy P.V., Westwell, Andrew D.
Published in Tetrahedron letters (17.12.2014)
Published in Tetrahedron letters (17.12.2014)
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Design, synthesis and preliminary antiviral screening of new N-phenylpyrazole and dihydroisoxazole derivatives
Rashad, Adel A, El-Sabbagh, Osama I, Baraka, Mohamed M, Ibrahim, Samy M, Pannecouque, Christophe, Andrei, Graciela, Snoeck, Robert, Balzarini, Jan, Mostafa, Ahmed
Published in Medicinal chemistry research (01.12.2010)
Published in Medicinal chemistry research (01.12.2010)
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ChemInform Abstract: Optimized Synthesis of Diamino-Triazinylmethyl Benzoates as Inhibitors of Rad6B Ubiquitin Conjugating Enzyme
Kothayer, Hend, Morelli, Matteo, Brahemi, Ghali, Elshanawani, Abdalla A., Abu Kull, Mansour E., El-Sabbagh, Osama I., Shekhar, Malathy P. V., Westwell, Andrew D.
Published in ChemInform (01.04.2015)
Published in ChemInform (01.04.2015)
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