Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors
Salem, Ibrahim M., Mostafa, Samia M., Salama, Ismail, El-Sabbagh, Osama I., Hegazy, Wael A. H., Ibrahim, Tarek S.
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2023)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2023)
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Synthesis and antiviral activity of new pyrazole and thiazole derivatives
El-Sabbagh, Osama I., Baraka, Mohamed M., Ibrahim, Samy M., Pannecouque, Christophe, Andrei, Graciela, Snoeck, Robert, Balzarini, Jan, Rashad, Adel A.
Published in European journal of medicinal chemistry (01.09.2009)
Published in European journal of medicinal chemistry (01.09.2009)
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The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme
Malebari, Azizah M., Ibrahim, Tarek S., Salem, Ibrahim M., Salama, Ismail, Khayyat, Ahdab N., Mostafa, Samia M., El-Sabbagh, Osama I., Darwish, Khaled M.
Published in Pharmaceuticals (Basel, Switzerland) (18.09.2020)
Published in Pharmaceuticals (Basel, Switzerland) (18.09.2020)
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New thiopyridine complexes: design, electrochemical preparation and biological assessment
El-Sabbagh, Osama I., Yamany, Yamany B., Eldeab, Hany A.
Published in Polish journal of chemical technology (01.12.2019)
Published in Polish journal of chemical technology (01.12.2019)
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Synthesis and Biological Evaluation of Some N-Arylpyrazoles and Pyrazolo[3,4-d]pyridazines as Anti-Inflammatory Agents
El-Sabbagh, Osama I., Mostafa, Samia, Abdel-Aziz, Hatem A., Ibrahim, Hany S., Elaasser, Mahmoud M.
Published in Archiv der Pharmazie (Weinheim) (01.09.2013)
Published in Archiv der Pharmazie (Weinheim) (01.09.2013)
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Synthesis of new multitarget-directed ligands containing thienopyrimidine nucleus for inhibition of 15-lipoxygenase, cyclooxygenases, and pro-inflammatory cytokines
Abdelkhalek, Ahmed S., Kothayer, Hend, Rezq, Samar, Orabi, Khaled Y., Romero, Damian G., El-Sabbagh, Osama I.
Published in European journal of medicinal chemistry (05.08.2023)
Published in European journal of medicinal chemistry (05.08.2023)
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Novel benzenesulfonamide and 1,2-benzisothiazol-3(2H)-one-1,1-dioxide derivatives as potential selective COX-2 inhibitors
Taher, Ehab S., Ibrahim, Tarek S., Fares, Mohamed, AL-Mahmoudy, Amany M.M., Radwan, Abdullah F., Orabi, Khaled Y., El-Sabbagh, Osama I.
Published in European journal of medicinal chemistry (01.06.2019)
Published in European journal of medicinal chemistry (01.06.2019)
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Human dihydrofolate reductase inhibition effect of 1-Phenylpyrazolo[3,4–d]pyrimidines: Synthesis, antitumor evaluation and molecular modeling study
Salem, Ibrahim M., Mostafa, Samia M., Salama, Ismail, El-Sabbagh, Osama I., A. H. Hegazy, Wael, Ibrahim, Tarek S.
Published in Bioorganic chemistry (01.12.2022)
Published in Bioorganic chemistry (01.12.2022)
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Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold
Ibrahim, Tarek S., Salem, Ibrahim M., Mostafa, Samia M., El-Sabbagh, Osama I., ElKhamisi, Mohamed K.M., Hegazy, Lamees, Elgendy, Bahaa
Published in Bioorganic chemistry (01.07.2020)
Published in Bioorganic chemistry (01.07.2020)
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Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides
Kothayer, Hend, Elshanawani, Abdalla A., Abu Kull, Mansour E., El-Sabbagh, Osama I., Shekhar, Malathy P.V., Brancale, Andrea, Jones, Arwyn T., Westwell, Andrew D.
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
Published in Bioorganic & medicinal chemistry letters (15.12.2013)
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Optimised synthesis of diamino-triazinylmethyl benzoates as inhibitors of Rad6B ubiquitin conjugating enzyme
Kothayer, Hend, Morelli, Matteo, Brahemi, Ghali, Elshanawani, Abdalla A., Abu Kull, Mansour E., El-Sabbagh, Osama I., Shekhar, Malathy P.V., Westwell, Andrew D.
Published in Tetrahedron letters (17.12.2014)
Published in Tetrahedron letters (17.12.2014)
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