Loss of hepatic Flcn protects against fibrosis and inflammation by activating autophagy pathways
Paquette, Mathieu, Yan, Ming, Ramírez-Reyes, Josué M J, El-Houjeiri, Leeanna, Biondini, Marco, Dufour, Catherine R, Jeong, Hyeonju, Pacis, Alain, Giguère, Vincent, Estall, Jennifer L, Siegel, Peter M, Audet-Walsh, Étienne, Pause, Arnim
Published in Scientific reports (28.10.2021)
Published in Scientific reports (28.10.2021)
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Journal Article
AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3
Paquette, Mathieu, El-Houjeiri, Leeanna, C. Zirden, Linda, Puustinen, Pietri, Blanchette, Paola, Jeong, Hyeonju, Dejgaard, Kurt, Siegel, Peter M., Pause, Arnim
Published in Autophagy (02.12.2021)
Published in Autophagy (02.12.2021)
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Journal Article
Folliculin impairs breast tumor growth by repressing TFE3-dependent induction of the Warburg effect and angiogenesis
El-Houjeiri, Leeanna, Biondini, Marco, Paquette, Mathieu, Kuasne, Helen, Pacis, Alain, Park, Morag, Siegel, Peter M, Pause, Arnim
Published in The Journal of clinical investigation (15.11.2021)
Published in The Journal of clinical investigation (15.11.2021)
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Journal Article
The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance
El-Houjeiri, Leeanna, Possik, Elite, Vijayaraghavan, Tarika, Paquette, Mathieu, Martina, José A., Kazan, Jalal M., Ma, Eric H., Jones, Russell, Blanchette, Paola, Puertollano, Rosa, Pause, Arnim
Published in Cell reports (Cambridge) (26.03.2019)
Published in Cell reports (Cambridge) (26.03.2019)
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Journal Article
HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin
Biondini, Marco, Kiepas, Alex, El-Houjeiri, Leeanna, Annis, Matthew G, Hsu, Brian E, Fortier, Anne-Marie, Morin, Geneviève, Martina, José A, Sirois, Isabelle, Aguilar-Mahecha, Adriana, Gruosso, Tina, McGuirk, Shawn, Rose, April A N, Tokat, Unal M, Johnson, Radia M, Sahin, Ozgur, Bareke, Eric, St-Pierre, Julie, Park, Morag, Basik, Mark, Majewski, Jacek, Puertollano, Rosa, Pause, Arnim, Huang, Sidong, Keler, Tibor, Siegel, Peter M
Published in Oncogene (18.03.2022)
Published in Oncogene (18.03.2022)
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Journal Article
Antitumor activities of the synthetic retinoid ST1926 in two-dimensional and three-dimensional human breast cancer models
Aouad, Patrick, Saikali, Melody, Abdel-Samad, Rana, Fostok, Sabreen, El-Houjeiri, Leeanna, Pisano, Claudio, Talhouk, Rabih, Darwiche, Nadine
Published in Anti-cancer drugs (01.08.2017)
Published in Anti-cancer drugs (01.08.2017)
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Journal Article
Abstract 1189: Combination treatments with retinoic acid and the synthetic retinoid ST1926 in 2D and 3D breast cancer models overcome retinoic acid resistance and eradicate breast cancer stem/progenitor cells
Aouad, Patrick, Saikali, Melody, Abdel-Samad, Rana, El–Houjeiri, Leeanna, Pisano, Claudio, Talhouk, Rabih, Darwiche, Nadine
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract 5140: Encapsulation of the atypical retinoid ST1926 in nanoparticles prolongs the survival of acute myeloid leukemia xenografted mice at multiple folds lower concentrations than the naked drug
El-Houjeiri, Leeanna, Saad, Walid, Hayar, Berthe, Aouad, Patrick, Tawil, Nadim, Abdel-Samad, Rana, Pisano, Claudio, Bazarbachi, Ali, Hajj, Hiba El, Darwiche, Nadine
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
FLCN Gene Ablation Reduces Fibrosis and Inflammation in a Diet-Induced NASH Model
Paquette, Mathieu, Yan, Ming, El-Houjeiri, Leeanna, Biondini, Marco, Ramírez-Reyes, Josué M J, Pacis, Alain, Jeong, Hyeonju, Estall, Jennifer L, Siegel, Peter M, Pause, Arnim
Published in bioRxiv (11.09.2020)
Published in bioRxiv (11.09.2020)
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The transcription factors TFEB and TFE3 link the FLCN-AMPK signaling axis to innate immune response and pathogen resistance
El-Houjeiri, Leeanna, Possik, Elite, Tarika Tarika Vijayaraghavan, Paquette, Mathieu, Martina, Jose A, Kazan, Jalal M, Ma, Eric H, Jones, Russell, Blanchette, Paola, Puertollano, Rosa, Pause, Arnim
Published in bioRxiv (06.11.2018)
Published in bioRxiv (06.11.2018)
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