Atrial‐like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial‐selective pharmacology
Devalla, Harsha D, Schwach, Verena, Ford, John W, Milnes, James T, El‐Haou, Said, Jackson, Claire, Gkatzis, Konstantinos, Elliott, David A, Chuva de Sousa Lopes, Susana M, Mummery, Christine L, Verkerk, Arie O, Passier, Robert
Published in EMBO molecular medicine (01.04.2015)
Published in EMBO molecular medicine (01.04.2015)
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Effect of selective IK,ACh inhibition by XAF‐1407 in an equine model of tachypacing‐induced persistent atrial fibrillation
Fenner, Merle Friederike, Carstensen, Helena, Dalgas Nissen, Sarah, Melis Hesselkilde, Eva, Scott Lunddahl, Christine, Adler Hess Jensen, Maja, Loft‐Andersen, Ameli Victoria, Sattler, Stefan Michael, Platonov, Pyotr, El‐Haou, Said, Jackson, Claire, Tang, Raymond, Kirby, Robert, Ford, John, Schotten, Ulrich, Milnes, James, Svane Sørensen, Ulrik, Jespersen, Thomas, Buhl, Rikke
Published in British journal of pharmacology (01.08.2020)
Published in British journal of pharmacology (01.08.2020)
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Journal Article
Rheumatic Heart Disease Screening by Echocardiography The Inadequacy of World Health Organization Criteria for Optimizing the Diagnosis of Subclinical Disease
MARIJON, Eloi, CELERMAJER, David S, TAFFLET, Muriel, EL-HAOU, Saïd, JANI, Dinesh N, FERREIRA, Beatriz, MOCUMBI, Ana-Olga, PAQUET, Christophe, SIDI, Daniel, JOUVEN, Xavier
Published in Circulation (New York, N.Y.) (25.08.2009)
Published in Circulation (New York, N.Y.) (25.08.2009)
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Journal Article
Kv4 Potassium Channels Form a Tripartite Complex With the Anchoring Protein SAP97 and CaMKII in Cardiac Myocytes
El-Haou, Saïd, Balse, Elise, Neyroud, Nathalie, Dilanian, Gilles, Gavillet, Bruno, Abriel, Hugues, Coulombe, Alain, Jeromin, Andreas, Hatem, Stéphane N
Published in Circulation research (27.03.2009)
Published in Circulation research (27.03.2009)
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Journal Article
Cholesterol modulates the recruitment of Kv1.5 channels from Rab11-associated recycling endosome in native atrial myocytes
Balse, Elise, El-Haou, Saïd, Dillanian, Gilles, Dauphin, Aurélien, Eldstrom, Jodene, Fedida, David, Coulombe, Alain, Hatem, Stéphane N
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2009)
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The anchoring protein SAP97 retains Kv1.5 channels in the plasma membrane of cardiac myocytes
Abi-Char, Joelle, El-Haou, Said, Balse, Elise, Neyroud, Nathalie, Vranckx, Roger, Coulombe, Alain, Hatem, Stephane N
Published in American journal of physiology. Heart and circulatory physiology (01.04.2008)
Published in American journal of physiology. Heart and circulatory physiology (01.04.2008)
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Journal Article
Response to Letters Regarding Article, “Rheumatic Heart Disease Screening by Echocardiography: The Inadequacy of World Health Organization Criteria for Optimizing the Diagnosis of Subclinical Disease”
Marijon, Eloi, Jouven, Xavier, Celermajer, David S., Tafflet, Muriel, El-Haou, Saïd, Jani, Dinesh, Ferreira, Beatriz, Mocumbi, Ana Olga, Sidi, Daniel, Paquet, Christophe
Published in Circulation (New York, N.Y.) (01.06.2010)
Published in Circulation (New York, N.Y.) (01.06.2010)
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Journal Article
SAP97 and Dystrophin Macromolecular Complexes Determine Two Pools of Cardiac Sodium Channels Nav1.5 in Cardiomyocytes
Petitprez, Séverine, Zmoos, Anne-Flore, Ogrodnik, Jakob, Balse, Elise, Raad, Nour, El-Haou, Said, Albesa, Maxime, Bittihn, Philip, Luther, Stefan, Lehnart, Stephan E, Hatem, Stéphane N, Coulombe, Alain, Abriel, Hugues
Published in Circulation research (04.02.2011)
Published in Circulation research (04.02.2011)
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The positive frequency-dependent electrophysiological effects of the IKur inhibitor XEN-D0103 are desirable for the treatment of atrial fibrillation
Ford, John, PhD, Milnes, James, PhD, El Haou, Said, PhD, Wettwer, Erich, PhD, Loose, Simone, MD, Matschke, Klaus, MD, Tyl, Benoit, MD, Round, Patrick, MBBS, Ravens, Ursula, MD
Published in Heart rhythm (01.02.2016)
Published in Heart rhythm (01.02.2016)
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Journal Article
Effect of selective I K,ACh inhibition by XAF-1407 in an equine model of tachypacing-induced persistent atrial fibrillation
Fenner, Merle Friederike, Carstensen, Helena, Dalgas Nissen, Sarah, Melis Hesselkilde, Eva, Scott Lunddahl, Christine, Adler Hess Jensen, Maja, Loft-Andersen, Ameli Victoria, Sattler, Stefan Michael, Platonov, Pyotr, El-Haou, Said, Jackson, Claire, Tang, Raymond, Kirby, Robert, Ford, John, Schotten, Ulrich, Milnes, James, Svane Sørensen, Ulrik, Jespersen, Thomas, Buhl, Rikke
Published in British journal of pharmacology (01.08.2020)
Published in British journal of pharmacology (01.08.2020)
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Journal Article
Enhancing Maturation and Translatability of Human Pluripotent Stem Cell-Derived Cardiomyocytes through a Novel Medium Containing Acetyl-CoA Carboxylase 2 Inhibitor
Correia, Cláudia, Christoffersson, Jonas, Tejedor, Sandra, El-Haou, Saïd, Matadamas-Guzman, Meztli, Nair, Syam, Dönnes, Pierre, Musa, Gentian, Rohman, Mattias, Sundqvist, Monika, Riddle, Rebecca B, Nugraha, Bramasta, Bellido, Ioritz Sorzabal, Johansson, Markus, Wang, Qing-Dong, Hidalgo, Alejandro, Jennbacken, Karin, Synnergren, Jane, Später, Daniela
Published in Cells (Basel, Switzerland) (13.08.2024)
Published in Cells (Basel, Switzerland) (13.08.2024)
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A benzopyran with antiarrhythmic activity is an inhibitor of Kir3.1-containing potassium channels
Cui, Meng, Alhamshari, Yaser, Cantwell, Lucas, EI-Haou, Said, Eptaminitaki, Giasemi C., Chang, Mengmeng, Abou-Assali, Obada, Tan, Haozhou, Xu, Keman, Masotti, Meghan, Plant, Leigh D., Thakur, Ganesh A., Noujaim, Sami F., Milnes, James, Logothetis, Diomedes E.
Published in The Journal of biological chemistry (01.01.2021)
Published in The Journal of biological chemistry (01.01.2021)
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Journal Article
Assessment of human induced pluripotent stem-cell derived cardiomyocytes for evaluating drug induced arrhythmias with multi-electrode array
El-Haou, Said, Kirby, Robert W., Webdale, Louise, Rogers, Marc
Published in Journal of pharmacological and toxicological methods (01.09.2019)
Published in Journal of pharmacological and toxicological methods (01.09.2019)
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Journal Article
Novel K+ Channel Targets in Atrial Fibrillation Drug Development--Where Are We?
El-Haou, Said, Ford, John W, Milnes, James T
Published in Journal of cardiovascular pharmacology (01.11.2015)
Published in Journal of cardiovascular pharmacology (01.11.2015)
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Journal Article
Electrophysiological characterisation of cellular dynamics international ventricular iCell2 iPSC-derived cardiomyocytes
Williams, Sarah, El Haou, Said, Webdale, Louise, Rogers, Marc, Sutton, Kathy
Published in Journal of pharmacological and toxicological methods (01.09.2018)
Published in Journal of pharmacological and toxicological methods (01.09.2018)
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Journal Article
Comprehensive profiling of axiogenesis ventricular vCor.4U iPSC-derived cardiomyocytes—From electrophysiology to phenotypic assays
El Haou, Said, Williams, Sarah, Webdale, Louise, Rogers, Marc, Sutton, Kathy
Published in Journal of pharmacological and toxicological methods (01.09.2018)
Published in Journal of pharmacological and toxicological methods (01.09.2018)
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Journal Article
CiPA Update: Refining In Vitro Cardiac Ion Channel Assays, In Silico Models and iPSC-Derived Cardiomyocyte Reagents for Improved Pro-arrhythmia Risk Prediction
Rogers, Marc, Kirby, Robert, El Haou, Said, Ridley, John, Williams, Sarah, Webdale, Louise, Sutton, Kathy
Published in Journal of pharmacological and toxicological methods (01.11.2017)
Published in Journal of pharmacological and toxicological methods (01.11.2017)
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Journal Article
Human Stem Cell-Derived Cardiomyocytes: In Vitro Assays and Screening Platforms for Exploring Ventricular and Atrial Phenotypes
Sutton, Kathy, Ridley, John, El Haou, Said, Williams, Sarah, Webdale, Louise, Rogers, Marc, Gibbons, George, Shao, Ying
Published in Journal of pharmacological and toxicological methods (01.11.2017)
Published in Journal of pharmacological and toxicological methods (01.11.2017)
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Journal Article
Differentiation and validation of human iPSC-derived atrial cardiomyocytes
Sutton, Kathy, El Haou, Said, Williams, Sarah, Devalla, Harsha, Stoelzle-Feix, Sonja, Juhasz, Krisztina, Doerr, Leo, Beckler, Matthias, Haarmann, Claudia, George, Michael, Passier, Robert, Fertig, Niels, Rogers, Marc
Published in Journal of pharmacological and toxicological methods (01.09.2018)
Published in Journal of pharmacological and toxicological methods (01.09.2018)
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