Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate
Rapino, Francesca, Zhou, Zhaoli, Roncero Sanchez, Ana Maria, Joiret, Marc, Seca, Christian, El Hachem, Najla, Valenti, Gianluca, Latini, Sara, Shostak, Kateryna, Geris, Liesbet, Li, Ping, Huang, Gang, Mazzucchelli, Gabriel, Baiwir, Dominique, Desmet, Christophe J., Chariot, Alain, Georges, Michel, Close, Pierre
Published in Nature communications (15.04.2021)
Published in Nature communications (15.04.2021)
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E2F1 inhibition mediates cell death of metastatic melanoma
Rouaud, Florian, Hamouda-Tekaya, Nedra, Cerezo, Michaël, Abbe, Patricia, Zangari, Joséphine, Hofman, Veronique, Ohanna, Mickaël, Mograbi, Baharia, El-Hachem, Najla, Benfodda, Zohra, Lebeau, Alexandre, Tulic, Meri K., Hofman, Paul, Bertolotto, Corine, Passeron, Thierry, Annicotte, Jean-Sébastien, Ballotti, Robert, Rocchi, Stéphane
Published in Cell death & disease (09.05.2018)
Published in Cell death & disease (09.05.2018)
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Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma
El-Hachem, Najla, Leclercq, Marine, Susaeta Ruiz, Miguel, Vanleyssem, Raphael, Shostak, Kateryna, Körner, Pierre-René, Capron, Coralie, Martin-Morales, Lorena, Roncarati, Patrick, Lavergne, Arnaud, Blomme, Arnaud, Turchetto, Silvia, Goffin, Eric, Thandapani, Palaniraja, Tarassov, Ivan, Nguyen, Laurent, Pirotte, Bernard, Chariot, Alain, Marine, Jean-Christophe, Herfs, Michael, Rapino, Francesca, Agami, Reuven, Close, Pierre
Published in Nature cell biology (01.07.2024)
Published in Nature cell biology (01.07.2024)
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Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis
Rosu, Adeline, El Hachem, Najla, Rapino, Francesca, Rouault-Pierre, Kevin, Jorssen, Joseph, Somja, Joan, Ramery, Eve, Thiry, Marc, Nguyen, Laurent, Jacquemyn, Maarten, Daelemans, Dirk, Adams, Christopher M, Bonnet, Dominique, Chariot, Alain, Close, Pierre, Bureau, Fabrice, Desmet, Christophe J
Published in The Journal of experimental medicine (01.03.2021)
Published in The Journal of experimental medicine (01.03.2021)
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FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells
Habel, Nadia, El-Hachem, Najla, Soysouvanh, Frédéric, Hadhiri-Bzioueche, Hanene, Giuliano, Serena, Nguyen, Sophie, Horák, Pavel, Gay, Anne-Sophie, Debayle, Delphine, Nottet, Nicolas, Béranger, Guillaume, Paillerets, Brigitte Bressac-de, Bertolotto, Corine, Ballotti, Robert
Published in Cell death and differentiation (01.06.2021)
Published in Cell death and differentiation (01.06.2021)
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Uncovering and deciphering the pro-invasive role of HACE1 in melanoma cells
El-Hachem, Najla, Habel, Nadia, Naiken, Tanesha, Bzioueche, Hanene, Cheli, Yann, Beranger, Guillaume E., Jaune, Emilie, Rouaud, Florian, Nottet, Nicolas, Reinier, Frédéric, Gaudel, Céline, Colosetti, Pascale, Bertolotto, Corine, Ballotti, Robert
Published in Cell death and differentiation (01.11.2018)
Published in Cell death and differentiation (01.11.2018)
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ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity
Cheli, Yann, Tulic, Meri K, El Hachem, Najla, Nottet, Nicolas, Jacquel, Arnaud, Gesson, Maeva, Strub, Thomas, Bille, Karine, Picard-Gauci, Alexandra, Montaudié, Henri, Beranger, Guillaume E, Passeron, Thierry, Close, Pierre, Bertolotto, Corine, Ballotti, Robert
Published in Molecular cancer (07.01.2021)
Published in Molecular cancer (07.01.2021)
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Correction to: ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity
Cheli, Yann, Tulic, Meri K, El Hachem, Najla, Nottet, Nicolas, Jacquel, Arnaud, Gesson, Maeva, Strub, Thomas, Bille, Karine, Picard-Gauci, Alexandra, Montaudié, Henri, Beranger, Guillaume E, Passeron, Thierry, Close, Pierre, Bertolotto, Corine, Ballotti, Robert
Published in Molecular cancer (27.01.2021)
Published in Molecular cancer (27.01.2021)
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S141: INHIBITION OF MYC TRANSLATION THROUGH TARGETING OF THE NEWLY IDENTIFIED PHB‐EIF4F COMPLEX AS THERAPEUTIC STRATEGY INCHRONIC LYMPHOCYTIC LEUKEMIA (CLL)
Largeot, Anne, Klapp, Vanessa, Viry, Elodie, Gonder, Susanne, Botana, Iria Fernandez, Blomme, Arnaud, Benzarti, Mohaned, Pierson, Sandrine, Duculty, Chloé, Marttila, Petra, Wierz, Marina, Gargiulo, Ernesto, Pagano, Giulia, An, Ning, El Hachem, Najla, Perez Hernandez, Daniel, Chakraborty, Supriya, Ysebaert, Loic, François, Jean‐Hugues, Cortez, Susan, Berchem, Guy, Efremov, Dimitar G, Dittmar, Gunnar, Szpakowska, Martyna, Chevigne, Andy, Nazarov, Petr V., Helleday, Thomas, Close, Pierre, Meiser, Johannes, Stamatopoulos, Basile, Désaubry, Laurent, Paggetti, Jérôme, Moussay, Etienne
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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mRNA Translation Reprogramming in Autosomal Dominant Polycystic Kidney Disease (ADPKD): FR-PO593
Leemans, Charlotte, El Hachem, Najla, Decuypere, Jean-Paul, Mekahli, Djalila, Jouret, Francois, Close, Pierre
Published in Journal of the American Society of Nephrology (01.10.2024)
Published in Journal of the American Society of Nephrology (01.10.2024)
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1236 Translation reprogramming in autosomal dominant polycystic kidney disease
Leemans, Charlotte, El Hachem, Najla, Mekahli, Djalila, Decuypere, Jean-Paul, Rapino, Francesca, Jouret, François, Close, Pierre
Published in Nephrology, dialysis, transplantation (23.05.2024)
Published in Nephrology, dialysis, transplantation (23.05.2024)
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Loss of Elp3 blocks intestinal tuft cell differentiation via an mTORC1-Atf4 axis
Wathieu, Caroline, Lavergne, Arnaud, Xu, Xinyi, Rolot, Marion, Nemazanyy, Ivan, Shostak, Kateryna, El Hachem, Najla, Maurizy, Chloé, Leemans, Charlotte, Close, Pierre, Nguyen, Laurent, Desmet, Christophe, Tielens, Sylvia, Dewals, Benjamin G, Chariot, Alain
Published in The EMBO journal (31.07.2024)
Published in The EMBO journal (31.07.2024)
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