In Situ Classification of Cell Types in Human Kidney Tissue Using 3D Nuclear Staining
Woloshuk, Andre, Khochare, Suraj, Almulhim, Aljohara F., McNutt, Andrew T., Dean, Dawson, Barwinska, Daria, Ferkowicz, Michael J., Eadon, Michael T., Kelly, Katherine J., Dunn, Kenneth W., Hasan, Mohammad A., El‐Achkar, Tarek M., Winfree, Seth
Published in Cytometry. Part A (01.07.2021)
Published in Cytometry. Part A (01.07.2021)
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Collagen fibrils and cell nuclei are entrapped within Randall's plaques but not in CaOx matrix overgrowth: A microscopic inquiry into Randall's plaque stone pathogenesis
Canela, Victor Hugo, Bledsoe, Sharon B., Worcester, Elaine M., Lingeman, James E., El‐Achkar, Tarek M., Williams, James C.
Published in Anatomical record (Hoboken, N.J. : 2007) (01.07.2022)
Published in Anatomical record (Hoboken, N.J. : 2007) (01.07.2022)
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Label‐free imaging of non‐deparaffinized sections of the human kidney to determine tissue quality and signatures of disease
Sabo, Angela R., Winfree, Seth, Bledsoe, Sharon B., Phillips, Carrie L., Lingeman, James E., Eadon, Michael T., Williams, James C., El‐Achkar, Tarek M.
Published in Physiological reports (01.02.2022)
Published in Physiological reports (01.02.2022)
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Demineralization and sectioning of human kidney stones: A molecular investigation revealing the spatial heterogeneity of the stone matrix
Canela, Victor Hugo, Bledsoe, Sharon B., Lingeman, James E., Gerber, Glenn, Worcester, Elaine M., El‐Achkar, Tarek M., Williams, James C.
Published in Physiological reports (01.01.2021)
Published in Physiological reports (01.01.2021)
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The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline
Janosevic, Danielle, Myslinski, Jered, McCarthy, Thomas W, Zollman, Amy, Syed, Farooq, Xuei, Xiaoling, Gao, Hongyu, Liu, Yun-Long, Collins, Kimberly S, Cheng, Ying-Hua, Winfree, Seth, El-Achkar, Tarek M, Maier, Bernhard, Melo Ferreira, Ricardo, Eadon, Michael T, Hato, Takashi, Dagher, Pierre C
Published in eLife (15.01.2021)
Published in eLife (15.01.2021)
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Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel
LaFavers, Kaice A, Macedo, Etienne, Garimella, Pranav S, Lima, Camila, Khan, Shehnaz, Myslinski, Jered, McClintick, Jeanette, Witzmann, Frank A, Winfree, Seth, Phillips, Carrie L, Hato, Takashi, Dagher, Pierre C, Wu, Xue-Ru, El-Achkar, Tarek M, Micanovic, Radmila
Published in Science translational medicine (02.10.2019)
Published in Science translational medicine (02.10.2019)
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Computational Pathology Fusing Spatial Technologies
Border, Samuel, Lucarelli, Nicholas, Eadon, Michael T, El-Achkar, Tarek M, Jain, Sanjay, Sarder, Pinaki
Published in Clinical journal of the American Society of Nephrology (01.05.2023)
Published in Clinical journal of the American Society of Nephrology (01.05.2023)
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Tamm-Horsfall Protein Regulates Mononuclear Phagocytes in the Kidney
Micanovic, Radmila, Khan, Shehnaz, Janosevic, Danielle, Lee, Maya E, Hato, Takashi, Srour, Edward F, Winfree, Seth, Ghosh, Joydeep, Tong, Yan, Rice, Susan E, Dagher, Pierre C, Wu, Xue-Ru, El-Achkar, Tarek M
Published in Journal of the American Society of Nephrology (01.03.2018)
Published in Journal of the American Society of Nephrology (01.03.2018)
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Tubular cross talk in acute kidney injury: a story of sense and sensibility
El-Achkar, Tarek M, Dagher, Pierre C
Published in American journal of physiology. Renal physiology (15.06.2015)
Published in American journal of physiology. Renal physiology (15.06.2015)
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A spatially anchored transcriptomic atlas of the human kidney papilla identifies significant immune injury in patients with stone disease
Canela, Victor Hugo, Bowen, William S., Ferreira, Ricardo Melo, Syed, Farooq, Lingeman, James E., Sabo, Angela R., Barwinska, Daria, Winfree, Seth, Lake, Blue B., Cheng, Ying-Hua, Gaut, Joseph P., Ferkowicz, Michael, LaFavers, Kaice A., Zhang, Kun, Coe, Fredric L., Worcester, Elaine, Jain, Sanjay, Eadon, Michael T., Williams, James C., El-Achkar, Tarek M.
Published in Nature communications (19.07.2023)
Published in Nature communications (19.07.2023)
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Uromodulin in Kidney Injury: An Instigator, Bystander, or Protector?
El-Achkar, Tarek M., MD, Wu, Xue-Ru, MD
Published in American journal of kidney diseases (01.03.2012)
Published in American journal of kidney diseases (01.03.2012)
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The kidney protects against sepsis by producing systemic uromodulin
LaFavers, Kaice A, Hage, Chadi A, Gaur, Varun, Micanovic, Radmila, Hato, Takashi, Khan, Shehnaz, Winfree, Seth, Doshi, Simit, Moorthi, Ranjani N, Twigg, Homer, Wu, Xue-Ru, Dagher, Pierre C, Srour, Edward F, El-Achkar, Tarek M
Published in American journal of physiology. Renal physiology (01.08.2022)
Published in American journal of physiology. Renal physiology (01.08.2022)
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Endotoxin Uptake by S1 Proximal Tubular Segment Causes Oxidative Stress in the Downstream S2 Segment
KALAKECHE, Rabih, HATO, Takashi, RHODES, Georges, DUNN, Kenneth W, EL-ACHKAR, Tarek M, PLOTKIN, Zoya, SANDOVAL, Ruben M, DAGHER, Pierre C
Published in Journal of the American Society of Nephrology (01.08.2011)
Published in Journal of the American Society of Nephrology (01.08.2011)
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Integration of spatial and single-cell transcriptomics localizes epithelial cell-immune cross-talk in kidney injury
Melo Ferreira, Ricardo, Sabo, Angela R, Winfree, Seth, Collins, Kimberly S, Janosevic, Danielle, Gulbronson, Connor J, Cheng, Ying-Hua, Casbon, Lauren, Barwinska, Daria, Ferkowicz, Michael J, Xuei, Xiaoling, Zhang, Chi, Dunn, Kenneth W, Kelly, Katherine J, Sutton, Timothy A, Hato, Takashi, Dagher, Pierre C, El-Achkar, Tarek M, Eadon, Michael T
Published in JCI insight (22.06.2021)
Published in JCI insight (22.06.2021)
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Tamm-Horsfall protein translocates to the basolateral domain of thick ascending limbs, interstitium, and circulation during recovery from acute kidney injury
El-Achkar, Tarek M, McCracken, Ruth, Liu, Yan, Heitmeier, Monique R, Bourgeois, Soline, Ryerse, Jan, Wu, Xue-Ru
Published in American journal of physiology. Renal physiology (15.04.2013)
Published in American journal of physiology. Renal physiology (15.04.2013)
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Journal Article
Tamm-Horsfall protein/uromodulin deficiency elicits tubular compensatory responses leading to hypertension and hyperuricemia
Liu, Yan, Goldfarb, David S, El-Achkar, Tarek M, Lieske, John C, Wu, Xue-Ru
Published in American journal of physiology. Renal physiology (01.06.2018)
Published in American journal of physiology. Renal physiology (01.06.2018)
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