Structure of the human metapneumovirus polymerase phosphoprotein complex
Pan, Junhua, Qian, Xinlei, Lattmann, Simon, El Sahili, Abbas, Yeo, Tiong Han, Jia, Huan, Cressey, Tessa, Ludeke, Barbara, Noton, Sarah, Kalocsay, Marian, Fearns, Rachel, Lescar, Julien
Published in Nature (London) (09.01.2020)
Published in Nature (London) (09.01.2020)
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Structural determinants for peptide-bond formation by asparaginyl ligases
Hemu, Xinya, Sahili, Abbas El, Hu, Side, Wong, Kaho, Chen, Yu, Wong, Yee Hwa, Zhang, Xiaohong, Serra, Aida, Goh, Boon Chong, Darwis, Dina A., Chen, Ming Wei, Sze, Siu Kwan, Liu, Chuan-Fa, Lescar, Julien, Tam, James P.
Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2019)
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Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling
Lim, Siew Pheng, Noble, Christian Guy, Seh, Cheah Chen, Soh, Tingjin Sherryl, El Sahili, Abbas, Chan, Grace Kar Yarn, Lescar, Julien, Arora, Rishi, Benson, Timothy, Nilar, Shahul, Manjunatha, Ujjini, Wan, Kah Fei, Dong, Hongping, Xie, Xuping, Shi, Pei-Yong, Yokokawa, Fumiaki
Published in PLoS pathogens (01.08.2016)
Published in PLoS pathogens (01.08.2016)
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Allosteric pyruvate kinase-based “logic gate” synergistically senses energy and sugar levels in Mycobacterium tuberculosis
Zhong, Wenhe, Cui, Liang, Goh, Boon Chong, Cai, Qixu, Ho, Peiying, Chionh, Yok Hian, Yuan, Meng, Sahili, Abbas El, Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D., Lescar, Julien, Dedon, Peter C.
Published in Nature communications (07.12.2017)
Published in Nature communications (07.12.2017)
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Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A11:01
Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad E. Z., Murali, Tanusya M., Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline T. H., Teo, Rachel Z. C., Wood, Kathryn J., Hanson, Brendon J., Gascoigne, Nicholas R. J., Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A.
Published in Nature communications (21.02.2019)
Published in Nature communications (21.02.2019)
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A Pyranose-2-Phosphate Motif Is Responsible for Both Antibiotic Import and Quorum-Sensing Regulation in Agrobacterium tumefaciens
El Sahili, Abbas, Li, Si-Zhe, Lang, Julien, Virus, Cornelia, Planamente, Sara, Ahmar, Mohammed, Guimaraes, Beatriz G, Aumont-Nicaise, Magali, Vigouroux, Armelle, Soulère, Laurent, Reader, John, Queneau, Yves, Faure, Denis, Moréra, Solange
Published in PLoS pathogens (01.08.2015)
Published in PLoS pathogens (01.08.2015)
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Novel Phage Lysin Abp013 against Acinetobacter baumannii
Chu, Joash Jun Keat, Poh, Wee Han, Hasnuddin, Nabilah Taqiah Binte, Hew, En Yi, Dam, Linh Chi, Sahili, Abbas El, Rice, Scott A, Goh, Boon Chong
Published in Antibiotics (Basel) (28.01.2022)
Published in Antibiotics (Basel) (28.01.2022)
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Agrobacterium uses a unique ligand-binding mode for trapping opines and acquiring a competitive advantage in the niche construction on plant host
Lang, Julien, Vigouroux, Armelle, Planamente, Sara, El Sahili, Abbas, Blin, Pauline, Aumont-Nicaise, Magali, Dessaux, Yves, Moréra, Solange, Faure, Denis
Published in PLoS pathogens (01.10.2014)
Published in PLoS pathogens (01.10.2014)
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Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase
Gharbi-Ayachi, Aicha, Santhanakrishnan, Sridhar, Wong, Yee Hwa, Chan, Kitti W K, Tan, Siok Thing, Bates, Roderick W, Vasudevan, Subhash G, El Sahili, Abbas, Lescar, Julien
Published in Journal of virology (14.10.2020)
Published in Journal of virology (14.10.2020)
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Structural basis for proenzyme maturation, substrate recognition, and ligation by a hyperactive peptide asparaginyl ligase
Hu, Side, El Sahili, Abbas, Kishore, Srujana, Wong, Yee Hwa, Hemu, Xinya, Goh, Boon Chong, Zhipei, Sang, Wang, Zhen, Tam, James P, Liu, Chuan-Fa, Lescar, Julien
Published in The Plant cell (29.11.2022)
Published in The Plant cell (29.11.2022)
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A highly conserved ligand-binding site for AccA transporters of antibiotic and quorum-sensing regulator in Agrobacterium leads to a different specificity
Moréra, Solange, Vigouroux, Armelle, Aumont-Nicaise, Magali, Ahmar, Mohammed, Meyer, Thibault, El Sahili, Abbas, Deicsics, Grégory, González-Mula, Almudena, Li, Sizhe, Doré, Jeanne, Sirigu, Serena, Legrand, Pierre, Penot, Camille, André, François, Faure, Denis, Soulère, Laurent, Queneau, Yves, Vial, Ludovic
Published in Biochemical journal (25.01.2024)
Published in Biochemical journal (25.01.2024)
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Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth
Ku, Zhiqiang, Xie, Xuping, Lin, Jianqing, Gao, Peng, Wu, Bin, El Sahili, Abbas, Su, Hang, Liu, Yang, Ye, Xiaohua, Tan, Eddie Yongjun, Li, Xin, Fan, Xuejun, Goh, Boon Chong, Xiong, Wei, Boyd, Hannah, Muruato, Antonio E., Deng, Hui, Xia, Hongjie, Zou, Jing, Kalveram, Birte K., Menachery, Vineet D., Zhang, Ningyan, Lescar, Julien, Shi, Pei-Yong, An, Zhiqiang
Published in Nature communications (22.09.2022)
Published in Nature communications (22.09.2022)
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Structural basis for high specificity of octopine binding in the plant pathogen Agrobacterium tumefaciens
Vigouroux, Armelle, El Sahili, Abbas, Lang, Julien, Aumont-Nicaise, Magali, Dessaux, Yves, Faure, Denis, Moréra, Solange
Published in Scientific reports (21.12.2017)
Published in Scientific reports (21.12.2017)
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On the design of a constitutively active peptide asparaginyl ligase for facile protein conjugation
Chua, Niying, Wong, Yee Hwa, El Sahili, Abbas, Liu, Chuan Fa, Lescar, Julien
Published in FEBS open bio (01.06.2023)
Published in FEBS open bio (01.06.2023)
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The SiaABC threonine phosphorylation pathway controls biofilm formation in response to carbon availability in Pseudomonas aeruginosa
Poh, Wee-Han, Lin, Jianqing, Colley, Brendan, Müller, Nicolai, Goh, Boon Chong, Schleheck, David, El Sahili, Abbas, Marquardt, Andreas, Liang, Yang, Kjelleberg, Staffan, Lescar, Julien, Rice, Scott A, Klebensberger, Janosch
Published in PloS one (06.11.2020)
Published in PloS one (06.11.2020)
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Synthesis of a non-natural glucose-2-phosphate ester able to dupe the acc system of Agrobacterium fabrum
Li, Si-Zhe, Vigouroux, Armelle, Ahmar, Mohammed, El Sahili, Abbas, Soulere, Laurent, Sago, Laila, Cornu, David, Morera, Solange, Queneau, Yves
Published in Organic & biomolecular chemistry (31.01.2019)
Published in Organic & biomolecular chemistry (31.01.2019)
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The protein kinase CK2 catalytic domain from Plasmodium falciparum: crystal structure, tyrosine kinase activity and inhibition
Ruiz-Carrillo, David, Lin, Jianqing, El Sahili, Abbas, Wei, Meng, Sze, Siu Kwan, Cheung, Peter C. F., Doerig, Christian, Lescar, Julien
Published in Scientific reports (09.05.2018)
Published in Scientific reports (09.05.2018)
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Inhibition of falcilysin from Plasmodium falciparum by interference with its closed-to-open dynamic transition
Lin, Jianqing, Yan, Xinfu, Chung, Zara, Liew, Chong Wai, El Sahili, Abbas, Pechnikova, Evgeniya V., Preiser, Peter R., Bozdech, Zbynek, Gao, Yong-Gui, Lescar, Julien
Published in Communications biology (31.08.2024)
Published in Communications biology (31.08.2024)
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Plasmodium vivax binds host CD98hc (SLC3A2) to enter immature red blood cells
Malleret, Benoît, El Sahili, Abbas, Tay, Matthew Zirui, Carissimo, Guillaume, Ong, Alice Soh Meoy, Novera, Wisna, Lin, Jianqing, Suwanarusk, Rossarin, Kosaisavee, Varakorn, Chu, Trang T. T., Sinha, Ameya, Howland, Shanshan Wu, Fan, Yiping, Gruszczyk, Jakub, Tham, Wai-Hong, Colin, Yves, Maurer-Stroh, Sebastian, Snounou, Georges, Ng, Lisa F. P., Chan, Jerry Kok Yen, Chacko, Ann-Marie, Lescar, Julien, Chandramohanadas, Rajesh, Nosten, François, Russell, Bruce, Rénia, Laurent
Published in Nature microbiology (01.08.2021)
Published in Nature microbiology (01.08.2021)
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