Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes
Barbour, Haithem, Daou, Salima, Hendzel, Michael, Affar, El Bachir
Published in Nature communications (23.11.2020)
Published in Nature communications (23.11.2020)
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Roles and mechanisms of BAP1 deubiquitinase in tumor suppression
Masclef, Louis, Ahmed, Oumaima, Estavoyer, Benjamin, Larrivée, Bruno, Labrecque, Nathalie, Nijnik, Anastasia, Affar, El Bachir
Published in Cell death and differentiation (01.02.2021)
Published in Cell death and differentiation (01.02.2021)
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Autodeubiquitination Protects the Tumor Suppressor BAP1 from Cytoplasmic Sequestration Mediated by the Atypical Ubiquitin Ligase UBE2O
Mashtalir, Nazar, Daou, Salima, Barbour, Haithem, Sen, Nadine N., Gagnon, Jessica, Hammond-Martel, Ian, Dar, Haider H., Therrien, Marc, Affar, El Bachir
Published in Molecular cell (08.05.2014)
Published in Molecular cell (08.05.2014)
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Starvation-induced proteasome assemblies in the nucleus link amino acid supply to apoptosis
Uriarte, Maxime, Sen Nkwe, Nadine, Tremblay, Roch, Ahmed, Oumaima, Messmer, Clémence, Mashtalir, Nazar, Barbour, Haithem, Masclef, Louis, Voide, Marion, Viallard, Claire, Daou, Salima, Abdelhadi, Djaileb, Ronato, Daryl, Paydar, Mohammadjavad, Darracq, Anaïs, Boulay, Karine, Desjardins-Lecavalier, Nicolas, Sapieha, Przemyslaw, Masson, Jean-Yves, Sergeev, Mikhail, Kwok, Benjamin H., Hulea, Laura, Mallette, Frédérick A., Milot, Eric, Larrivée, Bruno, Wurtele, Hugo, Affar, El Bachir
Published in Nature communications (30.11.2021)
Published in Nature communications (30.11.2021)
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Opto-magnetic capture of individual cells based on visual phenotypes
Binan, Loïc, Bélanger, François, Uriarte, Maxime, Lemay, Jean François, Pelletier De Koninck, Jean Christophe, Roy, Joannie, Affar, El Bachir, Drobetsky, Elliot, Wurtele, Hugo, Costantino, Santiago
Published in eLife (10.04.2019)
Published in eLife (10.04.2019)
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BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation
Bononi, Angela, Giorgi, Carlotta, Patergnani, Simone, Larson, David, Verbruggen, Kaitlyn, Tanji, Mika, Pellegrini, Laura, Signorato, Valentina, Olivetto, Federica, Pastorino, Sandra, Nasu, Masaki, Napolitano, Andrea, Gaudino, Giovanni, Morris, Paul, Sakamoto, Greg, Ferris, Laura K., Danese, Alberto, Raimondi, Andrea, Tacchetti, Carlo, Kuchay, Shafi, Pass, Harvey I., Affar, El Bachir, Yang, Haining, Pinton, Paolo, Carbone, Michele
Published in Nature (London) (22.06.2017)
Published in Nature (London) (22.06.2017)
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Surviving the host–pathogen interaction: Legionella uses its SidE arsenal to mediate phosphoribosyl-linked ubiquitination of Golgi proteins inducing organelle fragmentation
Ahmed, Oumaima, Masclef, Louis, Affar, El Bachir
Published in Cell death and differentiation (01.10.2021)
Published in Cell death and differentiation (01.10.2021)
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Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair
Yu, Helen, Pak, Helen, Hammond-Martel, Ian, Ghram, Mehdi, Rodrigue, Amélie, Daou, Salima, Barbour, Haithem, Corbeil, Luc, Hébert, Josée, Drobetsky, Elliot, Masson, Jean Yves, Noia, Javier M. Di, El Bachir Affar
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.2014)
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Limiting the DNA Double-Strand Break Resectosome for Genome Protection
Ronato, Daryl A., Mersaoui, Sofiane Y., Busatto, Franciele F., Affar, El Bachir, Richard, Stéphane, Masson, Jean-Yves
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.09.2020)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.09.2020)
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RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors
Patel, Parasvi S, Abraham, Karan Joshua, Guturi, Kiran Kumar Naidu, Halaby, Marie-Jo, Khan, Zahra, Palomero, Luis, Ho, Brandon, Duan, Shili, St-Germain, Jonathan, Algouneh, Arash, Mateo, Francesca, El Ghamrasni, Samah, Barbour, Haithem, Barnes, Daniel R, Beesley, Jonathan, Sanchez, Otto, Berman, Hal K, Brown, Grant W, Affar, El Bachir, Chenevix-Trench, Georgia, Antoniou, Antonis C, Arrowsmith, Cheryl H, Raught, Brian, Pujana, Miquel Angel, Mekhail, Karim, Hakem, Anne, Hakem, Razqallah
Published in The Journal of clinical investigation (01.02.2021)
Published in The Journal of clinical investigation (01.02.2021)
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The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression
Yu, Helen, Mashtalir, Nazar, Daou, Salima, Hammond-Martel, Ian, Ross, Julie, Sui, Guangchao, Hart, Gerald W., Rauscher, Frank J., Drobetsky, Elliot, Milot, Eric, Shi, Yang, Affar, El Bachir
Published in Molecular and Cellular Biology (01.11.2010)
Published in Molecular and Cellular Biology (01.11.2010)
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The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer
Daou, Salima, Hammond-Martel, Ian, Mashtalir, Nazar, Barbour, Haithem, Gagnon, Jessica, Iannantuono, NicholasV.G., Nkwe, Nadine Sen, Motorina, Alena, Pak, Helen, Yu, Helen, Wurtele, Hugo, Milot, Eric, Mallette, Frédérick A., Carbone, Michele, Affar, El Bachir
Published in The Journal of biological chemistry (27.11.2015)
Published in The Journal of biological chemistry (27.11.2015)
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Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1
Daou, Salima, Barbour, Haithem, Ahmed, Oumaima, Masclef, Louis, Baril, Caroline, Sen Nkwe, Nadine, Tchelougou, Daméhan, Uriarte, Maxime, Bonneil, Eric, Ceccarelli, Derek, Mashtalir, Nazar, Tanji, Mika, Masson, Jean-Yves, Thibault, Pierre, Sicheri, Frank, Yang, Haining, Carbone, Michele, Therrien, Marc, Affar, El Bachir
Published in Nature communications (22.10.2018)
Published in Nature communications (22.10.2018)
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ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers
Zhang, Yi, Xie, Guojia, Lee, Ji-Eun, Zandian, Mohamad, Sudarshan, Deepthi, Estavoyer, Benjamin, Benz, Caroline, Viita, Tiina, Asgaritarghi, Golareh, Lachance, Catherine, Messmer, Clémence, Simonetti, Leandro, Sinha, Vikrant Kumar, Lambert, Jean-Philippe, Chen, Yu-Wen, Wang, Shu-Ping, Ivarsson, Ylva, Affar, El Bachir, Côté, Jacques, Ge, Kai, Kutateladze, Tatiana G.
Published in Nature communications (07.06.2024)
Published in Nature communications (07.06.2024)
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Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine
Carbone, Michele, Amelio, Ivano, Affar, El Bachir, Brugarolas, James, Cannon-Albright, Lisa A, Cantley, Lewis C., Cavenee, Webster K., Chen, Zhijian, Croce, Carlo M., Andrea, Alan D’, Gandara, David, Giorgi, Carlotta, Jia, Wei, Lan, Qing, Mak, Tak Wah, Manley, James L., Mikoshiba, Katsuhiko, Onuchic, Jose N, Pass, Harvey I., Pinton, Paolo, Prives, Carol, Rothman, Nathaniel, Sebti, Said M., Turkson, James, Wu, Xifeng, Yang, Haining, Yu, Herbert, Melino, Gerry
Published in Cell death and differentiation (01.11.2018)
Published in Cell death and differentiation (01.11.2018)
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HIF1α-dependent hypoxia response in myeloid cells requires IRE1α
Mawambo, Gaëlle, Oubaha, Malika, Ichiyama, Yusuke, Blot, Guillaume, Crespo-Garcia, Sergio, Dejda, Agnieszka, Binet, François, Diaz-Marin, Roberto, Sawchyn, Christina, Sergeev, Mikhail, Juneau, Rachel, Kaufman, Randal J, Affar, El Bachir, Mallette, Frédérick A, Wilson, Ariel M, Sapieha, Przemyslaw
Published in Journal of neuroinflammation (21.06.2023)
Published in Journal of neuroinflammation (21.06.2023)
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