New pyrimidine/thiazole hybrids endowed with analgesic, anti‐inflammatory, and lower cardiotoxic activities: Design, synthesis, and COX‐2/sEH dual inhibition
Abdel‐Aziz, Salah A., Taher, Ehab S., Lan, Ping, El‐Koussi, Nawal A., Salem, Ola I. A., Gomaa, Hesham A. M., Youssif, Bahaa G. M.
Published in Archiv der Pharmazie (Weinheim) (01.07.2022)
Published in Archiv der Pharmazie (Weinheim) (01.07.2022)
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Design and synthesis of new dihydropyrimidine/sulphonamide hybrids as promising anti-inflammatory agents via dual mPGES-1/5-LOX inhibition
Al-Wahaibi, Lamya H, Elshamsy, Ali M, Ali, Taha F S, Youssif, Bahaa G M, Bräse, S, Abdel-Aziz, Mohamed, El-Koussi, Nawal A
Published in Frontiers in chemistry (2024)
Published in Frontiers in chemistry (2024)
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Design and Synthesis of New Dihydropyrimidine Derivatives with a Cytotoxic Effect as Dual EGFR/VEGFR‑2 Inhibitors
Al-Wahaibi, Lamya H., Elshamsy, Ali M., Ali, Taha F. S., Youssif, Bahaa G. M., Bräse, Stefan, Abdel-Aziz, Mohamed, El-Koussi, Nawal A.
Published in ACS omega (13.08.2024)
Published in ACS omega (13.08.2024)
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Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV
Hofny, Heba A., Mohamed, Mamdouh F.A., Gomaa, Hesham A.M., Abdel-Aziz, Salah A., Youssif, Bahaa G.M., El-koussi, Nawal A., Aboraia, Ahmed S.
Published in Bioorganic chemistry (01.07.2021)
Published in Bioorganic chemistry (01.07.2021)
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Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives bearing 1,3-thiazole moiety as novel anti-inflammatory EGFR inhibitors with cardiac safety profile
Abdel-Aziz, Salah A., Taher, Ehab S., Lan, Ping, Asaad, Gihan F., Gomaa, Hesham A.M., El-Koussi, Nawal A., Youssif, Bahaa G.M.
Published in Bioorganic chemistry (01.06.2021)
Published in Bioorganic chemistry (01.06.2021)
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Cu (I) catalyzed alkyne-azide 1,3-dipolar cycloaddition (CuAAC): Synthesis of 17α-[1-(substituted phenyl)-1,2,3-triazol-4-yl]-19-nor-testosterone-17β-yl acetates targeting progestational and antipro-liferative activities
Mohamed, Z.H., El-Koussi, Nawal A., Mahfouz, Nadia M., Youssef, Adel F., Abdel Jaleel, Gehad A., Shouman, Samia A.
Published in European journal of medicinal chemistry (05.06.2015)
Published in European journal of medicinal chemistry (05.06.2015)
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Brain Delivery of HIV Protease Inhibitors
Sheha, Mahmoud M., El-Koussi, Nawal A., Farag, Hassan H.
Published in Archiv der Pharmazie (Weinheim) (01.03.2003)
Published in Archiv der Pharmazie (Weinheim) (01.03.2003)
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Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity
Abdel-Hamid, Mohammed K., Abdel-Hafez, Atef A., El-Koussi, Nawal A., Mahfouz, Nadia M., Innocenti, Alessio, Supuran, Claudiu T.
Published in Bioorganic & medicinal chemistry (15.11.2007)
Published in Bioorganic & medicinal chemistry (15.11.2007)
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Quantitative structure-activity relationship (QSAR) studies on a series of 1,3,4-thiadiazole-2-thione derivatives as tumor-associated carbonic anhydrase IX inhibitors
Abdel-Hamid, Mohammed K., Abdel-Hafez, Atef A., El-Koussi, Nawal A., Mahfouz, Nadia M.
Published in Journal of enzyme inhibition and medicinal chemistry (01.06.2009)
Published in Journal of enzyme inhibition and medicinal chemistry (01.06.2009)
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HIV Protease Inhibitors: Peptidomimetic Drugs and Future Perspectives
ABDEL-RAHMAN, Hamdy M, AL-KARAMANY, Gamal S, EL-KOUSSI, Nawal A, YOUSSEF, Adel F, KISO, Yoshiaki
Published in Current medicinal chemistry (01.11.2002)
Published in Current medicinal chemistry (01.11.2002)
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Cu (I) catalyzed alkyne-azide 1,3-dipolar cycloaddition (CuAAC): Synthesis of 17 alpha-[1-(substituted phenyl)-1,2,3-triazol-4-yl]-19-nortestosterone-17 beta-yl acetates targeting progestational and antipro-liferative activities
Mohamed, Z. H., El-Koussi, Nawal A., Mahfouz, Nadia M., Youssef, Adel F., Jaleel, Gehad A. Abdel, Shouman, Samia A.
Published in European journal of medicinal chemistry (05.06.2015)
Published in European journal of medicinal chemistry (05.06.2015)
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A Novel Dipeptide-Based HIV Protease Inhibitor Containing Allophenylnorstatine
Abdel-Rahman, Hamdy M., El-Koussi, Nawal A., Alkaramany, Gamal S., Youssef, Adel F., Kiso, Yoshiaki
Published in ChemInform (12.04.2005)
Published in ChemInform (12.04.2005)
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