Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers
Goyenvalle, Aurélie, Griffith, Graziella, Babbs, Arran, Andaloussi, Samir El, Ezzat, Kariem, Avril, Aurélie, Dugovic, Branislav, Chaussenot, Rémi, Ferry, Arnaud, Voit, Thomas, Amthor, Helge, Bühr, Claudia, Schürch, Stefan, Wood, Matthew J A, Davies, Kay E, Vaillend, Cyrille, Leumann, Christian, Garcia, Luis
Published in Nature Medicine (01.03.2015)
Published in Nature Medicine (01.03.2015)
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Magazine Article
Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties
Nordin, Joel Z., M.D, Lee, Yi, BSc, Vader, Pieter, PhD, Mäger, Imre, PhD, Johansson, Henrik J., PhD, Heusermann, Wolf, PhD, Wiklander, Oscar P.B., M.D, Hällbrink, Mattias, PhD, Seow, Yiqi, DPhil, Bultema, Jarred J., PhD, Gilthorpe, Jonathan, PhD, Davies, Tim, MSc, Fairchild, Paul J., PhD, Gabrielsson, Susanne, PhD, Meisner-Kober, Nicole C., PhD, Lehtiö, Janne, PhD, Smith, C.I. Edvard, M.D., PhD, Wood, Matthew J.A., M.D., DPhil, Andaloussi, Samir EL, PhD
Published in Nanomedicine (01.05.2015)
Published in Nanomedicine (01.05.2015)
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A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA
de Jong, Olivier G., Murphy, Daniel E., Mäger, Imre, Willms, Eduard, Garcia-Guerra, Antonio, Gitz-Francois, Jerney J., Lefferts, Juliet, Gupta, Dhanu, Steenbeek, Sander C., van Rheenen, Jacco, El Andaloussi, Samir, Schiffelers, Raymond M., Wood, Matthew J. A., Vader, Pieter
Published in Nature communications (28.02.2020)
Published in Nature communications (28.02.2020)
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Journal Article
Optimisation of imaging flow cytometry for the analysis of single extracellular vesicles by using fluorescence-tagged vesicles as biological reference material
Görgens, André, Bremer, Michel, Ferrer-Tur, Rita, Murke, Florian, Tertel, Tobias, Horn, Peter A., Thalmann, Sebastian, Welsh, Joshua A., Probst, Christine, Guerin, Coralié, Boulanger, Chantal M., Jones, Jennifer C., Hanenberg, Helmut, Erdbrügger, Uta, Lannigan, Joanne, Ricklefs, Franz L., El-Andaloussi, Samir, Giebel, Bernd
Published in Journal of extracellular vesicles (01.01.2019)
Published in Journal of extracellular vesicles (01.01.2019)
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Journal Article
Self-Assembly into Nanoparticles Is Essential for Receptor Mediated Uptake of Therapeutic Antisense Oligonucleotides
Ezzat, Kariem, Aoki, Yoshitsugu, Koo, Taeyoung, McClorey, Graham, Benner, Leif, Coenen-Stass, Anna, O’Donovan, Liz, Lehto, Taavi, Garcia-Guerra, Antonio, Nordin, Joel, Saleh, Amer F, Behlke, Mark, Morris, John, Goyenvalle, Aurelie, Dugovic, Branislav, Leumann, Christian, Gordon, Siamon, Gait, Michael J, El−Andaloussi, Samir, Wood, Matthew JA
Published in Nano letters (08.07.2015)
Published in Nano letters (08.07.2015)
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Journal Article
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
Wiklander, Oscar P. B., Nordin, Joel Z., O'Loughlin, Aisling, Gustafsson, Ylva, Corso, Giulia, Mäger, Imre, Vader, Pieter, Lee, Yi, Sork, Helena, Seow, Yiqi, Heldring, Nina, Alvarez-Erviti, Lydia, Smith, CI Edvard, Le Blanc, Katarina, Macchiarini, Paolo, Jungebluth, Philipp, Wood, Matthew J. A., Andaloussi, Samir EL
Published in Journal of extracellular vesicles (01.01.2015)
Published in Journal of extracellular vesicles (01.01.2015)
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Journal Article
Advances in therapeutic applications of extracellular vesicles
Wiklander, Oscar P B, Brennan, Meadhbh Á, Lötvall, Jan, Breakefield, Xandra O, El Andaloussi, Samir
Published in Science translational medicine (15.05.2019)
Published in Science translational medicine (15.05.2019)
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Journal Article
Cargo-dependent cytotoxicity and delivery efficacy of cell-penetrating peptides: a comparative study
El-Andaloussi, Samir, Järver, Peter, Johansson, Henrik J, Langel, Ulo
Published in Biochemical journal (15.10.2007)
Published in Biochemical journal (15.10.2007)
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Journal Article
Novel endosomolytic compounds enable highly potent delivery of antisense oligonucleotides
Bost, Jeremy P., Ojansivu, Miina, Munson, Michael J., Wesén, Emelie, Gallud, Audrey, Gupta, Dhanu, Gustafsson, Oskar, Saher, Osama, Rädler, Julia, Higgins, Stuart G., Lehto, Taavi, Holme, Margaret N., Dahlén, Anders, Engkvist, Ola, Strömstedt, Per-Erik, Andersson, Shalini, Edvard Smith, C. I., Stevens, Molly M., Esbjörner, Elin K., Collén, Anna, El Andaloussi, Samir
Published in Communications biology (01.03.2022)
Published in Communications biology (01.03.2022)
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Journal Article
Publisher Correction: A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA
de Jong, Olivier G., Murphy, Daniel E., Mäger, Imre, Willms, Eduard, Garcia-Guerra, Antonio, Gitz-Francois, Jerney J., Lefferts, Juliet, Gupta, Dhanu, Steenbeek, Sander C., van Rheenen, Jacco, El Andaloussi, Samir, Schiffelers, Raymond M., Wood, Matthew J. A., Vader, Pieter
Published in Nature communications (31.03.2020)
Published in Nature communications (31.03.2020)
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Journal Article
Fine Tuning of Phosphorothioate Inclusion in 2′-O-Methyl Oligonucleotides Contributes to Specific Cell Targeting for Splice-Switching Modulation
Aoki, Yoshitsugu, Rocha, Cristina S. J., Lehto, Taavi, Miyatake, Shouta, Johansson, Henrik, Hashimoto, Yasumasa, Nordin, Joel Z., Mager, Imre, Aoki, Misako, Graham, McClorey, Sathyaprakash, Chaitra, Roberts, Thomas C., Wood, Matthew J. A., Behlke, Mark A., Andaloussi, Samir El
Published in Frontiers in physiology (13.10.2021)
Published in Frontiers in physiology (13.10.2021)
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Journal Article
High cerebrospinal amyloid-β 42 is associated with normal cognition in individuals with brain amyloidosis
Sturchio, Andrea, Dwivedi, Alok K., Young, Christina B., Malm, Tarja, Marsili, Luca, Sharma, Jennifer S., Mahajan, Abhimanyu, Hill, Emily J., Andaloussi, Samir EL, Poston, Kathleen L., Manfredsson, Fredric P., Schneider, Lon S., Ezzat, Kariem, Espay, Alberto J.
Published in EClinicalMedicine (01.08.2021)
Published in EClinicalMedicine (01.08.2021)
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Myeloid cells from Langerhans cell histiocytosis patients exhibit increased vesicle trafficking and an altered secretome capable of activating NK cells
Hagey, Daniel W, Kvedaraite, Egle, Akber, Mira, Görgens, André, Javadi, Joman, Von Bahr Greenwood, Tatiana, Björklund, Caroline, Åkefeldt, Selma Olsson, Hannegård-Hamrin, Tova, Arnell, Henrik, Dobra, Katalin, Herold, Nikolas, Svensson, Mattias, El Andaloussi, Samir, Henter, Jan-Inge, Lourda, Magda
Published in Haematologica (Roma) (2023)
Published in Haematologica (Roma) (2023)
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Journal Article
Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor‐KappaB Signaling
Anderson, Johnathon D., Johansson, Henrik J., Graham, Calvin S., Vesterlund, Mattias, Pham, Missy T., Bramlett, Charles S., Montgomery, Elizabeth N., Mellema, Matt S., Bardini, Renee L., Contreras, Zelenia, Hoon, Madeline, Bauer, Gerhard, Fink, Kyle D., Fury, Brian, Hendrix, Kyle J., Chedin, Frederic, EL‐Andaloussi, Samir, Hwang, Billie, Mulligan, Michael S., Lehtiö, Janne, Nolta, Jan A.
Published in Stem cells (Dayton, Ohio) (01.03.2016)
Published in Stem cells (Dayton, Ohio) (01.03.2016)
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Journal Article
Splice-switching efficiency and specificity for oligonucleotides with locked nucleic acid monomers
Guterstam, Peter, Lindgren, Maria, Johansson, Henrik, Tedebark, Ulf, Wengel, Jesper, El Andaloussi, Samir, Langel, Ulo
Published in Biochemical journal (01.06.2008)
Published in Biochemical journal (01.06.2008)
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Journal Article
Use of cell-penetrating-peptides in oligonucleotide splice switching therapy
El Andaloussi, Samir A, Hammond, Suzan M, Mäger, Imre, Wood, Matthew J A
Published in Current gene therapy (01.06.2012)
Published in Current gene therapy (01.06.2012)
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Journal Article
Induction of splice correction by cell‐penetrating peptide nucleic acids
El‐Andaloussi, Samir, Johansson, Henrik J., Lundberg, Pontus, Langel, Ülo
Published in The journal of gene medicine (01.10.2006)
Published in The journal of gene medicine (01.10.2006)
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Journal Article
Circulating Exosomal miR-20b-5p Is Elevated in Type 2 Diabetes and Could Impair Insulin Action in Human Skeletal Muscle
Katayama, Mutsumi, Wiklander, Oscar P B, Fritz, Tomas, Caidahl, Kenneth, El-Andaloussi, Samir, Zierath, Juleen R, Krook, Anna
Published in Diabetes (New York, N.Y.) (01.03.2019)
Published in Diabetes (New York, N.Y.) (01.03.2019)
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