Robust activation of microhomology-mediated end joining for precision gene editing applications
Ata, Hirotaka, Ekstrom, Thomas L, Martínez-Gálvez, Gabriel, Mann, Carla M, Dvornikov, Alexey V, Schaefbauer, Kyle J, Ma, Alvin C, Dobbs, Drena, Clark, Karl J, Ekker, Stephen C
Published in PLoS genetics (12.09.2018)
Published in PLoS genetics (12.09.2018)
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Journal Article
VLX600 Disrupts Homologous Recombination and Synergizes with PARP Inhibitors and Cisplatin by Inhibiting Histone Lysine Demethylases
Ekstrom, Thomas L, Pathoulas, Nicholas M, Huehls, Amelia M, Kanakkanthara, Arun, Karnitz, Larry M
Published in Molecular cancer therapeutics (01.09.2021)
Published in Molecular cancer therapeutics (01.09.2021)
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Journal Article
USP44 overexpression drives a MYC-like gene expression program in neuroblastoma through epigenetic reprogramming
Ekstrom, Thomas L, Hussain, Sajjad, Bedekovics, Tibor, Ali, Asma, Paolini, Lucia, Mahmood, Hina, Rosok, Raya M, Koster, Jan, Johnsen, Steven A, Galardy, Paul J
Published in Molecular cancer research (04.09.2024)
Published in Molecular cancer research (04.09.2024)
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Journal Article
BRCA1 Deficiency Upregulates NNMT, Which Reprograms Metabolism and Sensitizes Ovarian Cancer Cells to Mitochondrial Metabolic Targeting Agents
Kanakkanthara, Arun, Kurmi, Kiran, Ekstrom, Thomas L, Hou, Xiaonan, Purfeerst, Emma R, Heinzen, Ethan P, Correia, Cristina, Huntoon, Catherine J, O'Brien, Daniel, Wahner Hendrickson, Andrea E, Dowdy, Sean C, Li, Hu, Oberg, Ann L, Hitosugi, Taro, Kaufmann, Scott H, Weroha, S John, Karnitz, Larry M
Published in Cancer research (Chicago, Ill.) (01.12.2019)
Published in Cancer research (Chicago, Ill.) (01.12.2019)
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Journal Article
Repurposing Ceritinib Induces DNA Damage and Enhances PARP Inhibitor Responses in High-Grade Serous Ovarian Carcinoma
Kanakkanthara, Arun, Hou, Xiaonan, Ekstrom, Thomas L, Zanfagnin, Valentina, Huehls, Amelia M, Kelly, Rebecca L, Ding, Husheng, Larson, Melissa C, Vasmatzis, George, Oberg, Ann L, Kaufmann, Scott H, Mansfield, Aaron S, Weroha, S John, Karnitz, Larry M
Published in Cancer research (Chicago, Ill.) (15.01.2022)
Published in Cancer research (Chicago, Ill.) (15.01.2022)
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Journal Article
Interactive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer
Hamdan, Feda H, Abdelrahman, Amro M, Kutschat, Ana Patricia, Wang, Xin, Ekstrom, Thomas L, Jalan-Sakrikar, Nidhi, Wegner Wippel, Catherine, Taheri, Negar, Tamon, Liezel, Kopp, Waltraut, Aggrey-Fynn, Joana, Bhagwate, Aditya V, Alva-Ruiz, Roberto, Lynch, Isaac, Yonkus, Jennifer, Kosinsky, Robyn Laura, Gaedcke, Jochen, Hahn, Stephan A, Siveke, Jens T, Graham, Rondell, Najafova, Zeynab, Hessmann, Elisabeth, Truty, Mark J, Johnsen, Steven A
Published in Gut (01.06.2023)
Published in Gut (01.06.2023)
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Journal Article
Abstract 1481: MAPK and NF-kappaB signaling converge on the epigenome to transcriptionally activate genes involved in pancreatic cancer metastasis
Aggrey-Fynn, Joana E., Hamdan, Feda H., Wixom, Alexander Q., Ekstrom, Thomas L., Johnsen, Steven A.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Toward Precision Molecular Surgery: Robust, Selective Induction of Microhomology-mediated End Joining in vivo
Ata, Hirotaka, Ekstrom, Thomas L, Martinez-Galvez, Gabriel, Mann, Carla M, Dvornikov, Alexey V, Schaefbauer, Kyle J, Ma, Alvin C, Dobbs, Drena, Clark, Karl J, Ekker, Stephen C
Published in bioRxiv (16.04.2018)
Published in bioRxiv (16.04.2018)
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