Emerging Targets in Type 2 Diabetes and Diabetic Complications
Demir, Sevgican, Nawroth, Peter P., Herzig, Stephan, Ekim Üstünel, Bilgen
Published in Advanced science (01.09.2021)
Published in Advanced science (01.09.2021)
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Endothelial Notch signaling controls insulin transport in muscle
Hasan, Sana S, Jabs, Markus, Taylor, Jacqueline, Wiedmann, Lena, Leibing, Thomas, Nordström, Viola, Federico, Giuseppina, Roma, Leticia P, Carlein, Christopher, Wolff, Gretchen, Ekim‐Üstünel, Bilgen, Brune, Maik, Moll, Iris, Tetzlaff, Fabian, Gröne, Hermann‐Josef, Fleming, Thomas, Géraud, Cyrill, Herzig, Stephan, Nawroth, Peter P, Fischer, Andreas
Published in EMBO molecular medicine (07.04.2020)
Published in EMBO molecular medicine (07.04.2020)
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Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication
Loft, Anne, Alfaro, Ana Jimena, Schmidt, Søren Fisker, Pedersen, Felix Boel, Terkelsen, Mike Krogh, Puglia, Michele, Chow, Kan Kau, Feuchtinger, Annette, Troullinaki, Maria, Maida, Adriano, Wolff, Gretchen, Sakurai, Minako, Berutti, Riccardo, Ekim Üstünel, Bilgen, Nawroth, Peter, Ravnskjaer, Kim, Diaz, Mauricio Berriel, Blagoev, Blagoy, Herzig, Stephan
Published in Cell metabolism (03.08.2021)
Published in Cell metabolism (03.08.2021)
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The IKK‐related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists
Bodur, Cagri, Kazyken, Dubek, Huang, Kezhen, Ekim Ustunel, Bilgen, Siroky, Kate A, Tooley, Aaron Seth, Gonzalez, Ian E, Foley, Daniel H, Acosta‐Jaquez, Hugo A, Barnes, Tammy M, Steinl, Gabrielle K, Cho, Kae‐Won, Lumeng, Carey N, Riddle, Steven M, Myers, Martin G, Fingar, Diane C
Published in The EMBO journal (04.01.2018)
Published in The EMBO journal (04.01.2018)
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TSC22D4 interacts with Akt1 to regulate glucose metabolism
Demir, Sevgican, Wolff, Gretchen, Wieder, Annika, Maida, Adriano, Bühler, Lea, Brune, Maik, Hautzinger, Oksana, Feuchtinger, Annette, Poth, Tanja, Szendroedi, Julia, Herzig, Stephan, Ekim Üstünel, Bilgen
Published in Science advances (21.10.2022)
Published in Science advances (21.10.2022)
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Journal Article
Control of diabetic hyperglycaemia and insulin resistance through TSC22D4
Ekim Üstünel, Bilgen, Friedrich, Kilian, Maida, Adriano, Wang, Xiaoyue, Krones-Herzig, Anja, Seibert, Oksana, Sommerfeld, Anke, Jones, Allan, Sijmonsma, Tjeerd P., Sticht, Carsten, Gretz, Norbert, Fleming, Thomas, Nawroth, Peter P., Stremmel, Wolfgang, Rose, Adam J., Berriel-Diaz, Mauricio, Blüher, Matthias, Herzig, Stephan
Published in Nature communications (09.11.2016)
Published in Nature communications (09.11.2016)
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Journal Article
Lipocalin 13 enhances insulin secretion but is dispensable for systemic metabolic control
Bühler, Lea, Maida, Adriano, Vogl, Elena Sophie, Georgiadi, Anastasia, Takacs, Andrea, Kluth, Oliver, Schürmann, Annette, Feuchtinger, Annette, von Toerne, Christine, Tsokanos, Foivos-Filippos, Klepac, Katarina, Wolff, Gretchen, Sakurai, Minako, Ekim Üstünel, Bilgen, Nawroth, Peter, Herzig, Stephan
Published in Life science alliance (01.04.2021)
Published in Life science alliance (01.04.2021)
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Journal Article
A Hepatic GAbp-AMPK Axis Links Inflammatory Signaling to Systemic Vascular Damage
Niopek, Katharina, Üstünel, Bilgen Ekim, Seitz, Susanne, Sakurai, Minako, Zota, Annika, Mattijssen, Frits, Wang, Xiaoyue, Sijmonsma, Tjeerd, Feuchter, Yvonne, Gail, Anna M., Leuchs, Barbara, Niopek, Dominik, Staufer, Oskar, Brune, Maik, Sticht, Carsten, Gretz, Norbert, Müller-Decker, Karin, Hammes, Hans-Peter, Nawroth, Peter, Fleming, Thomas, Conkright, Michael D., Blüher, Matthias, Zeigerer, Anja, Herzig, Stephan, Berriel Diaz, Mauricio
Published in Cell reports (Cambridge) (08.08.2017)
Published in Cell reports (Cambridge) (08.08.2017)
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Journal Article
An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice
Rohm, Maria, Schäfer, Michaela, Laurent, Victor, Üstünel, Bilgen Ekim, Niopek, Katharina, Algire, Carolyn, Hautzinger, Oksana, Sijmonsma, Tjeerd P, Zota, Annika, Medrikova, Dasa, Pellegata, Natalia S, Ryden, Mikael, Kulyte, Agné, Dahlman, Ingrid, Arner, Peter, Petrovic, Natasa, Cannon, Barbara, Amri, Ez-Zoubir, Kemp, Bruce E, Steinberg, Gregory R, Janovska, Petra, Kopecky, Jan, Wolfrum, Christian, Blüher, Matthias, Berriel Diaz, Mauricio, Herzig, Stephan
Published in Nature medicine (01.10.2016)
Published in Nature medicine (01.10.2016)
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Semaphorin 3C exacerbates liver fibrosis
De Angelis Rigotti, Francesca, Wiedmann, Lena, Hubert, Max Ole, Vacca, Margherita, Hasan, Sana S, Moll, Iris, Carvajal, Silvia, Jiménez, Wladimiro, Starostecka, Maja, Billeter, Adrian T, Müller-Stich, Beat, Wolff, Gretchen, Ekim-Üstünel, Bilgen, Herzig, Stephan, Fandos-Ramo, Cristina, Krätzner, Ralph, Reich, Maria, Keitel-Anselmino, Verena, Heikenwälder, Mathias, Mogler, Carolin, Fischer, Andreas, Rodriguez-Vita, Juan
Published in Hepatology (Baltimore, Md.) (01.10.2023)
Published in Hepatology (Baltimore, Md.) (01.10.2023)
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Hepatocyte-specific activity of TSC22D4 triggers progressive NAFLD by impairing mitochondrial function
Wolff, Gretchen, Sakurai, Minako, Mhamane, Amit, Troullinaki, Maria, Maida, Adriano, Deligiannis, Ioannis K., Yin, Kelvin, Weber, Peter, Morgenstern, Jakob, Wieder, Annika, Kwon, Yun, Sekar, Revathi, Zeigerer, Anja, Roden, Michael, Blüher, Matthias, Volk, Nadine, Poth, Tanja, Hackert, Thilo, Wiedmann, Lena, De Angelis Rigotti, Francesca, Rodriguez-Vita, Juan, Fischer, Andreas, Mukthavaram, Rajesh, Limphong, Pattraranee, Tachikawa, Kiyoshi, Karmali, Priya, Payne, Joseph, Chivukula, Padmanabh, Ekim-Üstünel, Bilgen, Martinez-Jimenez, Celia P., Szendrödi, Julia, Nawroth, Peter, Herzig, Stephan
Published in Molecular metabolism (Germany) (01.06.2022)
Published in Molecular metabolism (Germany) (01.06.2022)
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Journal Article
Semaphorin 3C exacerbates liver fibrosis
Francesca De Angelis Rigotti, Wiedmann, Lena, Hubert, Max Ole, Vacca, Margherita, Hasan, Sana S, Moll, Iris, Carvajal, Silvia, Jiménez, Wladimiro, Starostecka, Maja, Billeter, Adrian T, Müller-Stich, Beat, Wolff, Gretchen, Bilgen Ekim-Üstünel, Herzig, Stephan, Mogler, Carolin, Fischer, Andreas, Rodriguez-Vita, Juan
Published in bioRxiv (23.05.2022)
Published in bioRxiv (23.05.2022)
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