Defining the mechanism of polymerization in the serpinopathies
Ekeowa, Ugo I., Freeke, Joanna, Miranda, Elena, Gooptu, Bibek, Bush, Matthew F., Pérez, Juan, Teckman, Jeff, Robinson, Carol V., Lomas, David A.
Published in Proceedings of the National Academy of Sciences - PNAS (05.10.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (05.10.2010)
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Journal Article
Structural Dynamics Associated with Intermediate Formation in an Archetypal Conformational Disease
Nyon, Mun Peak, Segu, Lakshmi, Cabrita, Lisa D., Lévy, Géraldine R., Kirkpatrick, John, Roussel, Benoit D., Patschull, Anathe O.M., Barrett, Tracey E., Ekeowa, Ugo I., Kerr, Richard, Waudby, Christopher A., Kalsheker, Noor, Hill, Marian, Thalassinos, Konstantinos, Lomas, David A., Christodoulou, John, Gooptu, Bibek
Published in Structure (London) (07.03.2012)
Published in Structure (London) (07.03.2012)
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Journal Article
A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with α1‐antitrypsin deficiency
Miranda, Elena, Pérez, Juan, Ekeowa, Ugo I., Hadzic, Nedim, Kalsheker, Noor, Gooptu, Bibek, Portmann, Bernard, Belorgey, Didier, Hill, Marian, Chambers, Susan, Teckman, Jeff, Alexander, Graeme J., Marciniak, Stefan J., Lomas, David A.
Published in Hepatology (Baltimore, Md.) (01.09.2010)
Published in Hepatology (Baltimore, Md.) (01.09.2010)
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Journal Article
Unravelling the twists and turns of the serpinopathies
Roussel, Benoit D., Irving, James A., Ekeowa, Ugo I., Belorgey, Didier, Haq, Imran, Ordóñez, Adriana, Kruppa, Antonina J., Duvoix, Annelyse, Rashid, Sheikh Tamir, Crowther, Damian C., Marciniak, Stefan J., Lomas, David A.
Published in The FEBS journal (01.10.2011)
Published in The FEBS journal (01.10.2011)
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Journal Article
α1-Antitrypsin deficiency, chronic obstructive pulmonary disease and the serpinopathies
Ekeowa, Ugo I., Gooptu, Bibek, Belorgey, Didier, Hägglöf, Peter, Karlsson-Li, Susanna, Miranda, Elena, Pérez, Juan, MacLeod, Ian, Kroger, Heike, Marciniak, Stefan J., Crowther, Damian C., Lomas, David A.
Published in Clinical science (1979) (01.06.2009)
Published in Clinical science (1979) (01.06.2009)
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Journal Article
Characterisation of serpin polymers in vitro and in vivo
Belorgey, Didier, Irving, James A., Ekeowa, Ugo I., Freeke, Joanna, Roussel, Benoit D., Miranda, Elena, Pérez, Juan, Robinson, Carol V., Marciniak, Stefan J., Crowther, Damian C., Michel, Claire H., Lomas, David A.
Published in Methods (San Diego, Calif.) (01.03.2011)
Published in Methods (San Diego, Calif.) (01.03.2011)
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Journal Article
The serpinopathies studying serpin polymerization in vivo
Irving, James A, Ekeowa, Ugo I, Belorgey, Didier, Haq, Imran, Gooptu, Bibek, Miranda, Elena, Pérez, Juan, Roussel, Benoit D, Ordóñez, Adriana, Dalton, Lucy E, Thomas, Sally E, Marciniak, Stefan J, Parfrey, Helen, Chilvers, Edwin R, Teckman, Jeffrey H, Alam, Sam, Mahadeva, Ravi, Rashid, S Tamir, Vallier, Ludovic, Lomas, David A
Published in Methods in enzymology (2011)
Published in Methods in enzymology (2011)
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Journal Article
α1-antitrypsin deficiency and inflammation
Ekeowa, Ugo I, Marciniak, Stefan J, Lomas, David A
Published in Expert review of clinical immunology (01.03.2011)
Published in Expert review of clinical immunology (01.03.2011)
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Journal Article
α(1)-antitrypsin deficiency and inflammation
Ekeowa, Ugo I, Marciniak, Stefan J, Lomas, David A
Published in Expert review of clinical immunology (01.03.2011)
Published in Expert review of clinical immunology (01.03.2011)
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Journal Article
Warfarin-induced skin necrosis
Mungalsingh, Catherine R, Bomford, Jamie, Nayagam, Jeremy, Masiello, Mirella, Ekeowa, Ugo I, Webster, Simon
Published in Clinical medicine (London, England) (01.02.2012)
Published in Clinical medicine (London, England) (01.02.2012)
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Journal Article
Targeting serpins in high-throughput and structure-based drug design
Chang, Yi-Pin, Mahadeva, Ravi, Patschull, Anathe O M, Nobeli, Irene, Ekeowa, Ugo I, McKay, Adam R, Thalassinos, Konstantinos, Irving, James A, Haq, Imran, Nyon, Mun Peak, Christodoulou, John, Ordóñez, Adriana, Miranda, Elena, Gooptu, Bibek
Published in Methods in enzymology (2011)
Published in Methods in enzymology (2011)
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Journal Article
I[+ or -].sub.1-antitrypsin deficiency and inflammation
Ekeowa, Ugo I, Marciniak, Stefan J, Lomas, David A
Published in Expert review of clinical immunology (01.03.2011)
Published in Expert review of clinical immunology (01.03.2011)
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Journal Article
α 1 -antitrypsin deficiency and inflammation
Ekeowa, Ugo I, Marciniak, Stefan J, Lomas, David A
Published in Expert review of clinical immunology (01.03.2011)
Published in Expert review of clinical immunology (01.03.2011)
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Journal Article
[alpha]1-antitrypsin deficiency and inflammation
Ekeowa, Ugo I, Marciniak, Stefan J, Lomas, David A
Published in Expert review of clinical immunology (01.03.2011)
Published in Expert review of clinical immunology (01.03.2011)
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Journal Article
alpha alpha sub(1)-antitrypsin deficiency and inflammation
Ekeowa, Ugo I, Marciniak, Stefan J, Lomas, David A
Published in Expert review of clinical immunology (01.03.2011)
Published in Expert review of clinical immunology (01.03.2011)
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Journal Article
lesson of the month (2): Warfarin-induced skin necrosis
Mungalsingh, Catherine R, Bomford, Jamie, Nayagam, Jeremy, Masiello, Mirella, Ekeowa, Ugo I, Webster, Simon
Published in Clinical medicine (London, England) (01.02.2012)
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Published in Clinical medicine (London, England) (01.02.2012)
Journal Article
A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with α 1 -antitrypsin deficiency
Miranda, Elena, Pérez, Juan, Ekeowa, Ugo I., Hadzic, Nedim, Kalsheker, Noor, Gooptu, Bibek, Portmann, Bernard, Belorgey, Didier, Hill, Marian, Chambers, Susan, Teckman, Jeff, Alexander, Graeme J., Marciniak, Stefan J., Lomas, David A.
Published in Hepatology (Baltimore, Md.) (01.09.2010)
Published in Hepatology (Baltimore, Md.) (01.09.2010)
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Journal Article
A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with alpha sub(1)-antitrypsin deficiency
Miranda, Elena, Perez, Juan, Ekeowa, Ugo I, Hadzic, Nedim, Kalsheker, Noor, Gooptu, Bibek, Portmann, Bernard, Belorgey, Didier, Hill, Marian, Chambers, Susan, Teckman, Jeff, Alexander, Graeme J, Marciniak, Stefan J, Lomas, David A
Published in Hepatology (Baltimore, Md.) (01.09.2010)
Published in Hepatology (Baltimore, Md.) (01.09.2010)
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Journal Article
A novel monoclonal antibody to characterize pathogenic polymers in liver disease associated with [alpha]1-antitrypsin deficiency
Miranda, Elena, Perez, Juan, Ekeowa, Ugo I, Hadzic, Nedim, Kalsheker, Noor, Gooptu, Bibek, Portmann, Bernard, Belorgey, Didier, Hill, Marian, Chambers, Susan, Teckman, Jeff, Alexander, Graeme J, Marciniak, Stefan J, Lomas, David A
Published in Hepatology (Baltimore, Md.) (01.09.2010)
Published in Hepatology (Baltimore, Md.) (01.09.2010)
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Journal Article