IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization
Eissmann, Moritz F., Dijkstra, Christine, Jarnicki, Andrew, Phesse, Toby, Brunnberg, Jamina, Poh, Ashleigh R., Etemadi, Nima, Tsantikos, Evelyn, Thiem, Stefan, Huntington, Nicholas D., Hibbs, Margaret L., Boussioutas, Alex, Grimbaldeston, Michele A., Buchert, Michael, O’Donoghue, Robert J. J., Masson, Frederick, Ernst, Matthias
Published in Nature communications (21.06.2019)
Published in Nature communications (21.06.2019)
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Journal Article
IL33 and Mast Cells-The Key Regulators of Immune Responses in Gastrointestinal Cancers?
Eissmann, Moritz F, Buchert, Michael, Ernst, Matthias
Published in Frontiers in immunology (03.07.2020)
Published in Frontiers in immunology (03.07.2020)
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Journal Article
A tuft cell - ILC2 signaling circuit provides therapeutic targets to inhibit gastric metaplasia and tumor development
O’Keefe, Ryan N., Carli, Annalisa L. E., Baloyan, David, Chisanga, David, Shi, Wei, Afshar-Sterle, Shoukat, Eissmann, Moritz F., Poh, Ashleigh R., Pal, Bhupinder, Seillet, Cyril, Locksley, Richard M., Ernst, Matthias, Buchert, Michael
Published in Nature communications (28.10.2023)
Published in Nature communications (28.10.2023)
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Journal Article
Stomach-Specific Activation of Oncogenic KRAS and STAT3-Dependent Inflammation Cooperatively Promote Gastric Tumorigenesis in a Preclinical Model
Thiem, Stefan, Eissmann, Moritz F, Elzer, Joachim, Jonas, Anna, Putoczki, Tracy L, Poh, Ashleigh, Nguyen, Paul, Preaudet, Adele, Flanagan, Dustin, Vincan, Elizabeth, Waring, Paul, Buchert, Michael, Jarnicki, Andrew, Ernst, Matthias
Published in Cancer research (Chicago, Ill.) (15.04.2016)
Published in Cancer research (Chicago, Ill.) (15.04.2016)
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Journal Article
Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines
Huber, Anne, Allam, Amr H., Dijkstra, Christine, Thiem, Stefan, Huynh, Jennifer, Poh, Ashleigh R., Konecnik, Joshua, Jacob, Saumya P., Busuttil, Rita, Liao, Yang, Chisanga, David, Shi, Wei, Alorro, Mariah G., Forrow, Stephen, Tauriello, Daniele V.F., Batlle, Eduard, Boussioutas, Alex, Williams, David S., Buchert, Michael, Ernst, Matthias, Eissmann, Moritz F.
Published in Cell reports (Cambridge) (27.08.2024)
Published in Cell reports (Cambridge) (27.08.2024)
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Journal Article
Generation of gene-of-interest knockouts in murine organoids using CRISPR-Cas9
Huber, Anne, Dijkstra, Christine, Ernst, Matthias, Eissmann, Moritz F.
Published in STAR protocols (17.03.2023)
Published in STAR protocols (17.03.2023)
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Journal Article
Inhibition of the SRC Kinase HCK Impairs STAT3-Dependent Gastric Tumor Growth in Mice
Poh, Ashleigh R, Dwyer, Amy R, Eissmann, Moritz F, Chand, Ashwini L, Baloyan, David, Boon, Louis, Murrey, Michael W, Whitehead, Lachlan, O'Brien, Megan, Lowell, Clifford A, Putoczki, Tracy L, Pixley, Fiona J, O'Donoghue, Robert J J, Ernst, Matthias
Published in Cancer immunology research (01.04.2020)
Published in Cancer immunology research (01.04.2020)
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Journal Article
Tumor Growth Remains Refractory to Myc Ablation in Host Macrophages
Morrow, Riley J, Allam, Amr H, Konecnik, Josh, Baloyan, David, Dijkstra, Christine, Eissmann, Moritz F, Jacob, Saumya P, O'Brien, Megan, Poh, Ashleigh R, Ernst, Matthias
Published in Cells (Basel, Switzerland) (17.12.2022)
Published in Cells (Basel, Switzerland) (17.12.2022)
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Journal Article
Induction of Fibroblast Growth Factor Receptor 4 by Helicobacter pylori via Signal Transducer and Activator of Transcription 3 With a Feedforward Activation Loop Involving SRC Signaling in Gastric Cancer
Zhang, Xing, Soutto, Mohammed, Chen, Zheng, Bhat, Nadeem, Zhu, Shoumin, Eissmann, Moritz F., Ernst, Matthias, Lu, Heng, Peng, Dunfa, Xu, Zekuan, El-Rifai, Wael
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2022)
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Journal Article
DCLK1 induces a pro-tumorigenic phenotype to drive gastric cancer progression
Afshar-Sterle, Shoukat, Carli, Annalisa L E, O'Keefe, Ryan, Tse, Janson, Fischer, Stefanie, Azimpour, Alexander I, Baloyan, David, Elias, Lena, Thilakasiri, Pathum, Patel, Onisha, Ferguson, Fleur M, Eissmann, Moritz F, Chand, Ashwini L, Gray, Nathanael S, Busuttil, Rita, Boussioutas, Alex, Lucet, Isabelle S, Ernst, Matthias, Buchert, Michael
Published in Science signaling (17.09.2024)
Published in Science signaling (17.09.2024)
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Journal Article
EHF is essential for epidermal and colonic epithelial homeostasis, and suppresses Apc -initiated colonic tumorigenesis
Reehorst, Camilla M., Nightingale, Rebecca, Luk, Ian Y., Jenkins, Laura, Koentgen, Frank, Williams, David S., Darido, Charbel, Tan, Fiona, Anderton, Holly, Chopin, Michael, Schoffer, Kael, Eissmann, Moritz F., Buchert, Michael, Mouradov, Dmitri, Sieber, Oliver M., Ernst, Matthias, Dhillon, Amardeep S., Mariadason, John M.
Published in Development (Cambridge) (15.06.2021)
Published in Development (Cambridge) (15.06.2021)
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Journal Article
Host IL11 Signaling Suppresses CD4 + T cell-Mediated Antitumor Responses to Colon Cancer in Mice
Huynh, Jennifer, Baloyan, David, Chisanga, David, Shi, Wei, O'Brien, Megan, Afshar-Sterle, Shoukat, Alorro, Mariah, Pang, Lokman, Williams, David S, Parslow, Adam C, Thilakasiri, Pathum, Eissmann, Moritz F, Boon, Louis, Masson, Frederick, Chand, Ashwini L, Ernst, Matthias
Published in Cancer immunology research (01.07.2021)
Published in Cancer immunology research (01.07.2021)
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Journal Article
Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration
Phesse, Toby J, Buchert, Michael, Stuart, Emma, Flanagan, Dustin J, Faux, Maree, Afshar-Sterle, Shoukat, Walker, Francesca, Zhang, Hui-Hua, Nowell, Cameron J, Jorissen, Robert, Tan, Chin Wee, Hirokawa, Yumiko, Eissmann, Moritz F, Poh, Ashleigh R, Malaterre, Jordane, Pearson, Helen B, Kirsch, David G, Provero, Paolo, Poli, Valeria, Ramsay, Robert G, Sieber, Oliver, Burgess, Antony W, Huszar, Dennis, Vincan, Elizabeth, Ernst, Matthias
Published in Science signaling (30.09.2014)
Published in Science signaling (30.09.2014)
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Journal Article
Interleukin 33 Signaling Restrains Sporadic Colon Cancer in an Interferon-γ-Dependent Manner
Eissmann, Moritz F, Dijkstra, Christine, Wouters, Merridee A, Baloyan, David, Mouradov, Dmitri, Nguyen, Paul M, Davalos-Salas, Mercedes, Putoczki, Tracy L, Sieber, Oliver M, Mariadason, John M, Ernst, Matthias, Masson, Frederick
Published in Cancer immunology research (01.04.2018)
Published in Cancer immunology research (01.04.2018)
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Journal Article
Generation of an inducible mouse model to reversibly silence Stat3
Alorro, Mariah G., Pierce, Thomas P., Eissmann, Moritz F., Dijkstra, Christine, Dickins, Ross A., Ernst, Matthias, Buchert, Michael, Masson, Frederic
Published in Genesis (New York, N.Y. : 2000) (01.04.2017)
Published in Genesis (New York, N.Y. : 2000) (01.04.2017)
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Journal Article
Mechanisms of cellular crosstalk in the gastric tumor microenvironment are mediated by YAP1 and STAT3
Thilakasiri, Pathum, O'Keefe, Ryan N, To, Sarah Q, Chisanga, David, Eissmann, Moritz F, Carli, Annalisa LE, Duscio, Belinda, Baloyan, David, Dmello, Rhynelle S, Williams, David, Mariadason, John, Poh, Ashleigh R, Pal, Bhupinder, Kile, Benjamin T, Vissers, Joseph Ha, Harvey, Kieran F, Buchert, Michael, Shi, Wei, Ernst, Matthias, Chand, Ashwini L
Published in Life science alliance (01.02.2024)
Published in Life science alliance (01.02.2024)
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Journal Article
Induction of Fibroblast Growth Factor Receptor 4 by Helicobacter pylori via Signal Transducer and Activator of Transcription 3 With a Feedforward Activation Loop Involving Steroid Receptor Coactivator Signaling in Gastric Cancer
Zhang, Xing, Soutto, Mohammed, Chen, Zheng, Bhat, Nadeem, Zhu, Shoumin, Eissmann, Moritz F., Ernst, Matthias, Lu, Heng, Peng, Dunfa, Xu, Zekuan, El-Rifai, Wael
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.09.2022)
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Journal Article
Tumor Growth Remains Refractory to IMyc/I Ablation in Host Macrophages
Morrow, Riley J, Allam, Amr H, Konecnik, Josh, Baloyan, David, Dijkstra, Christine, Eissmann, Moritz F, Jacob, Saumya P, O’Brien, Megan, Poh, Ashleigh R, Ernst, Matthias
Published in Cells (Basel, Switzerland) (01.12.2022)
Published in Cells (Basel, Switzerland) (01.12.2022)
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Journal Article
Malat1 fine-tunes bone homeostasis by orchestrating cellular crosstalk and the β-catenin-OPG/Jagged1 pathway
Qin, Yongli, Shirakawa, Jumpei, Xu, Cheng, Chen, Ruge, Ng, Courtney, Nakano, Shinichi, Elguindy, Mahmoud, Deng, Zhonghao, Prasanth, Kannanganattu V, Eissmann, Moritz F, Nakagawa, Shinichi, Ricci, William M, Zhao, Baohong
Published in Research square (03.05.2024)
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Published in Research square (03.05.2024)
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