Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway
Rickard, David J, Sehon, Clark A, Kasparcova, Viera, Kallal, Lorena A, Zeng, Xin, Montoute, Monica N, Chordia, Tushar, Poore, Derek D, Li, Hu, Wu, Zining, Eidam, Patrick M, Haile, Pamela A, Yu, Jong, Emery, John G, Marquis, Robert W, Gough, Peter J, Bertin, John
Published in PloS one (01.08.2013)
Published in PloS one (01.08.2013)
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Identification of selective small molecule inhibitors of the nucleotide-binding oligomerization domain 1 (NOD1) signaling pathway
Rickard, David J, Sehon, Clark A, Kasparcova, Viera, Kallal, Lorena A, Haile, Pamela A, Zeng, Xin, Montoute, Monica N, Poore, Derek D, Li, Hu, Wu, Zining, Eidam, Patrick M, Emery, John G, Marquis, Robert W, Gough, Peter J, Bertin, John
Published in PloS one (07.05.2014)
Published in PloS one (07.05.2014)
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Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer
Harris, Philip A, Marinis, Jill M, Lich, John D, Berger, Scott B, Chirala, Anirudh, Cox, Julie A, Eidam, Patrick M, Finger, Joshua N, Gough, Peter J, Jeong, Jae U, Kang, James, Kasparcova, Viera, Leister, Lara K, Mahajan, Mukesh K, Miller, George, Nagilla, Rakesh, Ouellette, Michael T, Reilly, Michael A, Rendina, Alan R, Rivera, Elizabeth J, Sun, Helen H, Thorpe, James H, Totoritis, Rachel D, Wang, Wei, Wu, Dongling, Zhang, Daohua, Bertin, John, Marquis, Robert W
Published in ACS medicinal chemistry letters (13.06.2019)
Published in ACS medicinal chemistry letters (13.06.2019)
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Crystal structures of human RIP2 kinase catalytic domain complexed with ATP-competitive inhibitors: Foundations for understanding inhibitor selectivity
Charnley, Adam K., Convery, Máire A., Lakdawala Shah, Ami, Jones, Emma, Hardwicke, Philip, Bridges, Angela, Ouellette, Michael, Totoritis, Rachel, Schwartz, Benjamin, King, Bryan W., Wisnoski, David D., Kang, James, Eidam, Patrick M., Votta, Bartholomew J., Gough, Peter J., Marquis, Robert W., Bertin, John, Casillas, Linda
Published in Bioorganic & medicinal chemistry (01.11.2015)
Published in Bioorganic & medicinal chemistry (01.11.2015)
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HETEROCYCLIC AMIDES AS KINASE INHIBITORS
RAMANJULU JOSHI M, HARRIS PHILIP ANTHONY, SEHON CLARK A, KANG JIANXING, BANDYOPADHYAY DEEPAK, GOUGH PETER J, KING BRYAN WAYNE, LEISTER LARA KATHRYN, SINGHAUS JR. ROBERT, EIDAM PATRICK M, RAHMAN ATTIQ, LAKDAWALA SHAH AMI, ZHANG DAOHUA, JEONG JAE U, MARQUIS JR. ROBERT W
Year of Publication 22.02.2019
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Year of Publication 22.02.2019
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키나제 억제제로서의 헤테로시클릭 아미드
FAUCHER NICOLAS ERIC, HARRIS PHILIP ANTHONY, SEHON CLARK A, KING BRYAN W, BANDYOPADHYAY DEEPAK, DONCHE FREDERIC G, EIDAM PATRICK M, DAUGAN ALAIN CLAUDE MARIE, ANDERSON NIALL ANDREW, GEORGE NICOLAS S, WHITE GEMMA VICTORIA, WISNOSKI DAVID DUFF, JEONG JAE U
Year of Publication 12.01.2018
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Year of Publication 12.01.2018
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Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase
Harris, Philip A, Faucher, Nicolas, George, Nicolas, Eidam, Patrick M, King, Bryan W, White, Gemma V, Anderson, Niall A, Bandyopadhyay, Deepak, Beal, Allison M, Beneton, Veronique, Berger, Scott B, Campobasso, Nino, Campos, Sebastien, Capriotti, Carol A, Cox, Julie A, Daugan, Alain, Donche, Frederic, Fouchet, Marie-Hélène, Finger, Joshua N, Geddes, Brad, Gough, Peter J, Grondin, Pascal, Hoffman, Bonnie L, Hoffman, Sandra J, Hutchinson, Susan E, Jeong, Jae U, Jigorel, Emilie, Lamoureux, Pauline, Leister, Lara K, Lich, John D, Mahajan, Mukesh K, Meslamani, Jamel, Mosley, Julie E, Nagilla, Rakesh, Nassau, Pamela M, Ng, Sze-Ling, Ouellette, Michael T, Pasikanti, Kishore K, Potvain, Florent, Reilly, Michael A, Rivera, Elizabeth J, Sautet, Stéphane, Schaeffer, Michelle C, Sehon, Clark A, Sun, Helen, Thorpe, James H, Totoritis, Rachel D, Ward, Paris, Wellaway, Natalie, Wisnoski, David D, Woolven, James M, Bertin, John, Marquis, Robert W
Published in Journal of medicinal chemistry (23.05.2019)
Published in Journal of medicinal chemistry (23.05.2019)
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HETEROCYCLIC AMIDES AS KINASE INHIBITORS
RAMANJULU JOSHI M, HARRIS PHILIP ANTHONY, SEHON CLARK A, KANG JIANXING, BANDYOPADHYAY DEEPAK, GOUGH PETER J, KING BRYAN WAYNE, LEISTER LARA KATHRYN, SINGHAUS JR. ROBERT, EIDAM PATRICK M, RAHMAN ATTIQ, LAKDAWALA SHAH AMI, ZHANG DAOHUA, JEONG JAE U, MARQUIS JR. ROBERT W
Year of Publication 23.10.2015
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Year of Publication 23.10.2015
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AMINO QUINAZOLINES AS KINASE INHIBITORS
RAMANJULU JOSHI M, CHARNLEY ADAM KENNETH, DEMARTINO MICHAEL P, BURY MICHAEL JONATHAN, HAILE PAMELA A, CASILLAS LINDA N, EIDAM PATRICK M, MARQUIS ROBERT W. JR, DONG XIAOYANG, SHAH AMI LAKDAWALA, WANG GREN, SINGHAUS ROBERT R. JR, ROMANO JOSEPH J
Year of Publication 08.05.2014
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Year of Publication 08.05.2014
Patent
Identification of Selective Small Molecule Inhibitors of the Nucleotide-Binding Oligomerization Domain 1
Rickard, David J, Sehon, Clark A, Kasparcova, Viera, Kallal, Lorena A, Haile, Pamela A, Zeng, Xin, Montoute, Monica N, Poore, Derek D, Li, Hu, Wu, Zining, Eidam, Patrick M, Emery, John G, Marquis, Robert W, Gough, Peter J, Bertin, John
Published in PloS one (07.05.2014)
Published in PloS one (07.05.2014)
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Journal Article
Identification of Benzimidazole Diamides as Selective Inhibitors of the Nucleotide-Binding Oligomerization Domain 2
Rickard, David J, Sehon, Clark A, Kasparcova, Viera, Kallal, Lorena A, Zeng, Xin, Montoute, Monica N, Chordia, Tushar, Poore, Derek D, Li, Hu, Wu, Zining, Eidam, Patrick M, Haile, Pamela A, Yu, Jong, Emery, John G, Marquis, Robert W, Gough, Peter J, Bertin, John
Published in PloS one (01.08.2013)
Published in PloS one (01.08.2013)
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HETEROCYCLIC AMIDES AS KINASE INHIBITORS
JEONG, JAE U, HARRIS, PHILIP ANTHONY, WHITE, GEMMA VICTORIA, FAUCHER, NICOLAS ERIC, ANDERSON, NIALL ANDREW, DONCHE, FREDERIC G, KING, BRYAN W, EIDAM, PATRICK M, WISNOSKI, DAVID DUFF, SEHON, CLARK A, GEORGE, NICOLAS S, BANDYOPADHYAY, DEEPAK, DAUGAN, ALAIN CLAUDE-MARIE
Year of Publication 02.01.2024
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Year of Publication 02.01.2024
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HETEROCYCLIC AMIDES AS KINASE INHIBITORS
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Year of Publication 20.04.2023
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Year of Publication 20.04.2023
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The oxa-Pictet-Spengler reaction of 1-(3-furyl)alkan-2-ols
Miles, WH, Heinsohn, SK, Brennan, MK, Swarr, DT, Eidam, PM, Gelato, KA
Published in Synthesis (Stuttgart) (2002)
Published in Synthesis (Stuttgart) (2002)
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Heterocyclic amides as kinase inhibitors
Sehon, Clark A, Daugan, Alain Claude-Marie, Harris, Philip Anthony, White, Gemma Victoria, Eidam, Patrick M, Anderson, Niall Andrew, Bandyopadhyay, Deepak, Donche, Frederic G, George, Nicolas S, King, Bryan W, Jeong, Jae U, Faucher, Nicolas Eric, Wisnoski, David Duff
Year of Publication 01.11.2022
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Year of Publication 01.11.2022
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HETEROCYCLIC AMIDES AS KINASE INHIBITORS
BRYAN W. KING, CLARK A. SEHON, FREDERIC G. DONCHE, NICOLAS ERIC FAUCHER, NIALL ANDREW ANDERSON, NICOLAS S. GEORGE, DAVID DUFF WISNOSKI, ALAIN CLAUDE-MARIE DAUGAN, JAE U. JEONG, GEMMA VICTORIA WHITE, PATRICK M. EIDAM, PHILIP ANTHONY HARRIS, DEEPAK BANDYOPADHYAY
Year of Publication 25.07.2022
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Year of Publication 25.07.2022
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HETEROCYCLIC AMIDES AS KINASE INHIBITORS
JEONG, JAE U, HARRIS, PHILIP ANTHONY, KANG, JIANXING, LEISTER, LARA KATHRYN, KING, BRYAN WAYNE, SINGHAUS, JR., ROBERT, MARQUIS, JR., ROBERT W, LAKDAWALA SHAH, AMI, RAHMAN, ATTIQ, GOUGH, PETER J, EIDAM, PATRICK M, SEHON, CLARK A, RAMANJULU, JOSHI M, ZHANG, DAOHUA, BANDYOPADHYAY, DEEPAK
Year of Publication 11.01.2023
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Year of Publication 11.01.2023
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HETEROCYCLIC AMIDES AS KINASE INHIBITORS
SEHON, Clark A, HARRIS, Philip Anthony, DAUGAN, Alain Claude-Marie, WHITE, Gemma Victoria, WISNOSKI, David Duff, DONCHE, Frederic G, FAUCHER, Nicolas Eric, BANDYOPADHYAY, Deepak, ANDERSON, Niall Andrew, EIDAM, Patrick M, GEORGE, Nicolas S, JEONG, Jae U, KING, Bryan W
Year of Publication 25.11.2021
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Year of Publication 25.11.2021
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HETEROCYCLIC AMIDES AS KINASE INHIBITORS
JEONG, JAE U, MARQUIS, ROBERT W, HARRIS, PHILIP ANTHONY, KANG, JIANXING, LEISTER, LARA KATHRYN, SINGHAUS, ROBERT, KING, BRYAN WAYNE, LAKDAWALA SHAH, AMI, RAHMAN, ATTIQ, GOUGH, PETER J, EIDAM, PATRICK M, SEHON, CLARK A, RAMANJULU, JOSHI M, ZHANG, DAOHUA, BANDYOPADHYAY, DEEPAK
Year of Publication 12.10.2021
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Year of Publication 12.10.2021
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