Autophagy in Huntington disease and huntingtin in autophagy
Martin, Dale D.O, Ladha, Safia, Ehrnhoefer, Dagmar E, Hayden, Michael R
Published in Trends in neurosciences (Regular ed.) (01.01.2015)
Published in Trends in neurosciences (Regular ed.) (01.01.2015)
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EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity
Bieschke, Jan, Russ, Jenny, Friedrich, Ralf P, Ehrnhoefer, Dagmar E, Wobst, Heike, Neugebauer, Katja, Wanker, Erich E
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (27.04.2010)
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Author Correction: Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates
Limorenko, Galina, Tatli, Meltem, Kolla, Rajasekhar, Nazarov, Sergey, Weil, Marie-Theres, Schöndorf, David C., Geist, Daniela, Reinhardt, Peter, Ehrnhoefer, Dagmar E., Stahlberg, Henning, Gasparini, Laura, Lashuel, Hilal A.
Published in Nature communications (30.05.2024)
Published in Nature communications (30.05.2024)
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Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin
Talantova, Maria, Kaul, Marcus, Yao, Dongdong, Xia, Peng, Ehrnhoefer, Dagmar E, Zaidi, Rameez, Lipton, Stuart A, Graham, Rona K, Tong, Gary, Zhang, Dongxian, Clemente, Arjay, Okamoto, Shu-ichi, Hayden, Michael R, Pouladi, Mahmoud A, Vincent Chen, H-S
Published in Nature medicine (01.12.2009)
Published in Nature medicine (01.12.2009)
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Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates
Limorenko, Galina, Tatli, Meltem, Kolla, Rajasekhar, Nazarov, Sergey, Weil, Marie-Theres, Schöndorf, David C., Geist, Daniela, Reinhardt, Peter, Ehrnhoefer, Dagmar E., Stahlberg, Henning, Gasparini, Laura, Lashuel, Hilal A.
Published in Nature communications (04.07.2023)
Published in Nature communications (04.07.2023)
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A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer's disease brain
Ercan-Herbst, Ebru, Ehrig, Jens, Schöndorf, David C, Behrendt, Annika, Klaus, Bernd, Gomez Ramos, Borja, Prat Oriol, Nuria, Weber, Christian, Ehrnhoefer, Dagmar E
Published in Acta neuropathologica communications (03.12.2019)
Published in Acta neuropathologica communications (03.12.2019)
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Asparagine endopeptidase cleaves tau at N167 after uptake into microglia
Behrendt, Annika, Bichmann, Maria, Ercan-Herbst, Ebru, Haberkant, Per, Schöndorf, David C., Wolf, Michael, Fahim, Salma A., Murolo, Enrico, Ehrnhoefer, Dagmar E.
Published in Neurobiology of disease (01.10.2019)
Published in Neurobiology of disease (01.10.2019)
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A validated antibody panel for the characterization of tau post-translational modifications
Ercan, Ebru, Eid, Sameh, Weber, Christian, Kowalski, Alexandra, Bichmann, Maria, Behrendt, Annika, Matthes, Frank, Krauss, Sybille, Reinhardt, Peter, Fulle, Simone, Ehrnhoefer, Dagmar E
Published in Molecular neurodegeneration (21.11.2017)
Published in Molecular neurodegeneration (21.11.2017)
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Journal Article
Dual truncation of tau by caspase-2 accelerates its CHIP-mediated degradation
Reinhardt, Lydia, Musacchio, Fabrizio, Bichmann, Maria, Behrendt, Annika, Ercan-Herbst, Ebru, Stein, Juliane, Becher, Isabelle, Haberkant, Per, Mader, Julia, Schöndorf, David C., Schmitt, Melanie, Korffmann, Jürgen, Reinhardt, Peter, Pohl, Christian, Savitski, Mikhail, Klein, Corinna, Gasparini, Laura, Fuhrmann, Martin, Ehrnhoefer, Dagmar E.
Published in Neurobiology of disease (15.06.2023)
Published in Neurobiology of disease (15.06.2023)
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Journal Article
Green tea (−)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models
Ehrnhoefer, Dagmar E., Duennwald, Martin, Markovic, Phoebe, Wacker, Jennifer L., Engemann, Sabine, Roark, Margaret, Legleiter, Justin, Marsh, J. Lawrence, Thompson, Leslie M., Lindquist, Susan, Muchowski, Paul J., Wanker, Erich E.
Published in Human molecular genetics (15.09.2006)
Published in Human molecular genetics (15.09.2006)
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Journal Article
HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response
Rotblat, Barak, Southwell, Amber L., Ehrnhoefer, Dagmar E., Skotte, Niels H., Metzler, Martina, Franciosi, Sonia, Leprivier, Gabriel, Somasekharan, Syam Prakash, Barokas, Adi, Yu Deng, Tang, Tiffany, Mathers, Joan, Cetinbas, Naniye, Daugaard, Mads, Kwok, Brian, Li, Liheng, Carnie, Christopher J., Fink, Dieter, Nitsch, Roberto, Galpin, Jason D., Ahern, Christopher A., Melino, Gerry, Penninger, Josef M., Hayden, Michael R., Sorensen, Poul H.
Published in Proceedings of the National Academy of Sciences - PNAS (25.02.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (25.02.2014)
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SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer's disease
Bichmann, Maria, Prat Oriol, Nuria, Ercan-Herbst, Ebru, Schöndorf, David C, Gomez Ramos, Borja, Schwärzler, Vera, Neu, Marie, Schlüter, Annabelle, Wang, Xue, Jin, Liang, Hu, Chenqi, Tian, Yu, Ried, Janina S, Haberkant, Per, Gasparini, Laura, Ehrnhoefer, Dagmar E
Published in Molecular neurodegeneration (02.07.2021)
Published in Molecular neurodegeneration (02.07.2021)
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Journal Article
Partial rescue of some features of Huntington Disease in the genetic absence of caspase-6 in YAC128 mice
Wong, Bibiana K.Y, Ehrnhoefer, Dagmar E, Graham, Rona K, Martin, Dale D.O, Ladha, Safia, Uribe, Valeria, Stanek, Lisa M, Franciosi, Sonia, Qiu, Xiaofan, Deng, Yu, Kovalik, Vlad, Zhang, Weining, Pouladi, Mahmoud A, Shihabuddin, Lamya S, Hayden, Michael R
Published in Neurobiology of disease (01.04.2015)
Published in Neurobiology of disease (01.04.2015)
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Journal Article
Correction: Tau seed amplification assay reveals relationship between seeding and pathological forms of tau in Alzheimer's disease brain
Frey, Bryan, Holzinger, David, Taylor, Keenan, Ehrnhoefer, Dagmar E, Striebinger, Andreas, Biesinger, Sandra, Gasparini, Laura, O'Neill, Michael J, Wegner, Florian, Barghorn, Stefan, Höglinger, Günter U, Heym, Roland G
Published in Acta neuropathologica communications (15.07.2024)
Published in Acta neuropathologica communications (15.07.2024)
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Journal Article
Tau seed amplification assay reveals relationship between seeding and pathological forms of tau in Alzheimer's disease brain
Frey, Bryan, Holzinger, David, Taylor, Keenan, Ehrnhoefer, Dagmar E, Striebinger, Andreas, Biesinger, Sandra, Gasparini, Laura, O'Neill, Michael J, Wegner, Florian, Barghorn, Stefan, Höglinger, Günter U, Heym, Roland G
Published in Acta neuropathologica communications (14.11.2023)
Published in Acta neuropathologica communications (14.11.2023)
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Journal Article
Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease
Ehrnhoefer, Dagmar E, Martin, Dale D O, Schmidt, Mandi E, Qiu, Xiaofan, Ladha, Safia, Caron, Nicholas S, Skotte, Niels H, Nguyen, Yen T N, Vaid, Kuljeet, Southwell, Amber L, Engemann, Sabine, Franciosi, Sonia, Hayden, Michael R
Published in Acta neuropathologica communications (06.03.2018)
Published in Acta neuropathologica communications (06.03.2018)
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Journal Article
Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice
URIBE, Valeria, WONG, Bibiana K. Y, YU DENG, FRANCIOSI, Sonia, BISSADA, Nagat, SPREEUW, Amanda, WEINING ZHANG, EHRNHOEFER, Dagmar E, VAID, Kuljeet, MILLER, Freda D, DESHMUKH, Mohanish, HOWLAND, David, GRAHAM, Rona K, HARDEN, Michael R, CUSACK, Corey L, SKOTTE, Niels H, POULADI, Mahmoud A, YUANYUN XIE, FEINBERG, Konstantin, YIMIAO OU, YINGBIN OUYANG
Published in Human molecular genetics (01.05.2012)
Published in Human molecular genetics (01.05.2012)
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Journal Article
NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease
Pouladi, Mahmoud A, Brillaud, Elsa, Xie, Yuanyun, Conforti, Paola, Graham, Rona K, Ehrnhoefer, Dagmar E, Franciosi, Sonia, Zhang, Weining, Poucheret, Patrick, Compte, Elsa, Maurel, Jean-Claude, Zuccato, Chiara, Cattaneo, Elena, Néri, Christian, Hayden, Michael R
Published in Neurobiology of disease (01.12.2012)
Published in Neurobiology of disease (01.12.2012)
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Journal Article
Generation of an induced pluripotent stem cell cohort suitable to investigate sporadic Alzheimer's Disease
Schöndorf, David C., Elschami, Myriam, Schieck, Maximilian, Ercan-Herbst, Ebru, Weber, Christian, Riesinger, Yasmin, Kalman, Sara, Steinemann, Doris, Ehrnhoefer, Dagmar E.
Published in Stem cell research (01.01.2019)
Published in Stem cell research (01.01.2019)
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