RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT
Kryshtal, Dmytro O, Blackwell, Daniel J, Egly, Christian L, Smith, Abigail N, Batiste, Suzanne M, Johnston, Jeffrey N, Laver, Derek R, Knollmann, Bjorn C
Published in Circulation research (05.02.2021)
Published in Circulation research (05.02.2021)
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Journal Article
The proteostasis interactomes of trafficking-deficient variants of the voltage-gated potassium channel KV11.1 associated with long QT syndrome
Egly, Christian L., Barny, Lea A., Do, Tri, McDonald, Eli F., Knollmann, Björn C., Plate, Lars
Published in The Journal of biological chemistry (01.07.2024)
Published in The Journal of biological chemistry (01.07.2024)
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Journal Article
High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel KV11.1
Kozek, Krystian A., Glazer, Andrew M., Ng, Chai-Ann, Blackwell, Daniel, Egly, Christian L., Vanags, Loren R., Blair, Marcia, Mitchell, Devyn, Matreyek, Kenneth A., Fowler, Douglas M., Knollmann, Bjorn C., Vandenberg, Jamie I., Roden, Dan M., Kroncke, Brett M.
Published in Heart rhythm (01.12.2020)
Published in Heart rhythm (01.12.2020)
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Journal Article
A High-Throughput Screening Assay to Identify Drugs that Can Treat Long QT Syndrome Caused by Trafficking-Deficient KV11.1 (hERG) Variants
Egly, Christian L, Blackwell, Daniel J, Schmeckpeper, Jeffrey, Delisle, Brian P, Weaver, C David, Knollmann, Björn C
Published in Molecular pharmacology (01.04.2022)
Published in Molecular pharmacology (01.04.2022)
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Journal Article
Eicosanoid-Regulated Myeloid ENaC and Isolevuglandin Formation in Human Salt-Sensitive Hypertension
Ertuglu, Lale A, Pitzer Mutchler, Ashley, Jamison, Sydney, Laffer, Cheryl L, Elijovich, Fernando, Saleem, Mohammad, Blackwell, Daniel J, Kryshtal, Dmytro O, Egly, Christian L, Sahinoz, Melis, Sheng, Quanhu, Wanjalla, Celestine N, Pakala, Suman, Yu, Justin, Gutierrez, Orlando M, Kleyman, Thomas R, Knollmann, Björn C, Ikizler, T Alp, Kirabo, Annet
Published in Hypertension (Dallas, Tex. 1979) (01.03.2024)
Published in Hypertension (Dallas, Tex. 1979) (01.03.2024)
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Journal Article
A High-Throughput Screening Assay to Identify Drugs that Can Treat Long QT Syndrome Caused by Trafficking-Deficient K V 11.1 (hERG) Variants
Egly, Christian L, Blackwell, Daniel J, Schmeckpeper, Jeffrey, Delisle, Brian P, Weaver, C David, Knollmann, Björn C
Published in Molecular pharmacology (01.04.2022)
Published in Molecular pharmacology (01.04.2022)
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Journal Article
PKC-dependent Phosphorylation of the H1 Histamine Receptor Modulates TRPC6 Activity
Chen, Xingjuan, Egly, Christian, Riley, Ashley M, Li, Wennan, Tewson, Paul, Hughes, Thomas E, Quinn, Anne Marie, Obukhov, Alexander G
Published in Cells (Basel, Switzerland) (04.04.2014)
Published in Cells (Basel, Switzerland) (04.04.2014)
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Journal Article
PO-05-178 DECIPHERING THERAPEUTIC RESCUE PATTERNS FOR LONG QT SYNDROME: A COMPREHENSIVE ANALYSIS OF KCNH2 MISSENSE VARIANTS AND THEIR RESPONSE TO CHAPERONE THERAPEUTICS
Shen, Alex, Egly, Christian, Ullah, Rizwan, Vanags, Loren R., Mitchell, Devyn W., Woo, Suah, Ku, Matthew, Patel, Nidhi, Venumuddala, Aakash, O'Neill, Matthew, Knollmann, Bjorn C., Kroncke, Brett
Published in Heart rhythm (01.05.2024)
Published in Heart rhythm (01.05.2024)
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Journal Article
RYR2 Channel Inhibition Is the Principal Mechanism 0f Flecainide Action in CPVT
Kryshtal, Dmytro O., Blackwell, Daniel J., Egly, Christian L., Smith, Abigail N., Batiste, Suzanne M., Johnston, Jeffrey N., Laver, Derek R., Knollmann, Bjorn C.
Published in Circulation research (10.12.2020)
Published in Circulation research (10.12.2020)
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Journal Article
Abstract 15420: Resolving a Controversy: Inhibition of Cardiac Ryanodine Receptors is the Principal Mechanism of Antiarrhythmic Action of Flecainide in Catecholaminergic Polymorphic Ventricular Tachycardia
Kryshtal, Dmytro O, Blackwell, Daniel J, Egly, Christian L, Smith, Abigail N, Batiste, Suzanne M, Johnston, Jeffrey N, Laver, Derek R, Knollmann, Bjorn C
Published in Circulation (New York, N.Y.) (17.11.2020)
Published in Circulation (New York, N.Y.) (17.11.2020)
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Journal Article
Progesterone Metabolites Inhibit the Human Ether-a-go-go-Related Gene and Predict QT Interval Length
Shugg, Tyler, Egly, Christian, Stamatkin, Chris W, Patil, Avinash S, Tisdale, James E, Overholser, Brian R
Published in Journal of clinical pharmacology (01.05.2020)
Published in Journal of clinical pharmacology (01.05.2020)
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Journal Article
High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel K V 11.1
Kozek, Krystian A, Glazer, Andrew M, Ng, Chai-Ann, Blackwell, Daniel, Egly, Christian L, Vanags, Loren R, Blair, Marcia, Mitchell, Devyn, Matreyek, Kenneth A, Fowler, Douglas M, Knollmann, Bjorn C, Vandenberg, Jamie I, Roden, Dan M, Kroncke, Brett M
Published in Heart rhythm (01.12.2020)
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Published in Heart rhythm (01.12.2020)
Journal Article
Estimating the Posttest Probability of Long QT Syndrome Diagnosis for Rare KCNH2 Variants
Kozek, Krystian, Wada, Yuko, Sala, Luca, Denjoy, Isabelle, Egly, Christian, O'Neill, Matthew J, Aiba, Takeshi, Shimizu, Wataru, Makita, Naomasa, Ishikawa, Taisuke, Crotti, Lia, Spazzolini, Carla, Kotta, Maria-Christina, Dagradi, Federica, Castelletti, Silvia, Pedrazzini, Matteo, Gnecchi, Massimiliano, Leenhardt, Antoine, Salem, Joe-Elie, Ohno, Seiko, Zuo, Yi, Glazer, Andrew M, Mosley, Jonathan D, Roden, Dan M, Knollmann, Bjorn C, Blume, Jeffrey D, Extramiana, Fabrice, Schwartz, Peter J, Horie, Minoru, Kroncke, Brett M
Published in Circulation. Genomic and precision medicine (01.08.2021)
Published in Circulation. Genomic and precision medicine (01.08.2021)
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Journal Article
The Pharmaceutical Industry: A Pharmacy Student's Guide
Egly, Christian, Kaakeh, Yaman
Published in Purdue Journal of Service-Learning and International Engagement (01.09.2018)
Published in Purdue Journal of Service-Learning and International Engagement (01.09.2018)
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Journal Article
Abstract 20786: Progesterone Metabolites Alter Activation Gating of the Human Ether-a-go-go-Related Gene (hERG)-Related Current
Egly, Christian, Shugg, Tyler, Stamatkin, Chris W, Patil, Avinash S, Tisdale, James E, Overholser, Brian R
Published in Circulation (New York, N.Y.) (11.11.2016)
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Published in Circulation (New York, N.Y.) (11.11.2016)
Journal Article