SGK2, 14-3-3, and HUWE1 Cooperate to Control the Localization, Stability, and Function of the Oncoprotein PTOV1
Pennington, Katie L, McEwan, Colten M, Woods, James, Muir, Colin M, Pramoda Sahankumari, A G, Eastmond, Riley, Balasooriya, Eranga R, Egbert, Christina M, Kaur, Sandeep, Heaton, Tyler, McCormack, Katherine K, Piccolo, Stephen R, Kurokawa, Manabu, Andersen, Joshua L
Published in Molecular cancer research (01.02.2022)
Published in Molecular cancer research (01.02.2022)
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Journal Article
TNK1 negatively regulates TBK1 at ubiquitin condensates
Lopez-Palacios, Tania, Egbert, Christina M, Chan, Tsz-Yin, Ashworth, Spencer, Vaughan, Alec, Andersen, Joshua
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Fusion crystallization reveals the behavior of both the 1TEL crystallization chaperone and the TNK1 UBA domain
Nawarathnage, Supeshala, Tseng, Yi Jie, Soleimani, Sara, Smith, Tobin, Pedroza Romo, Maria J, Abiodun, Wisdom O, Egbert, Christina M, Madhusanka, Deshan, Bunn, Derick, Woods, Bridger, Tsubaki, Evan, Stewart, Cameron, Brown, Seth, Doukov, Tzanko, Andersen, Joshua L, Moody, James D
Published in Structure (London) (07.12.2023)
Published in Structure (London) (07.12.2023)
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Integrating Clinical Cancer and PTM Proteomics Data Identifies a Mechanism of ACK1 Kinase Activation
Balasooriya, Eranga R, Madhusanka, Deshan, López-Palacios, Tania P, Eastmond, Riley J, Jayatunge, Dasun, Owen, Jake J, Gashler, Jack S, Egbert, Christina M, Bulathsinghalage, Chanaka, Liu, Lu, Piccolo, Stephen R, Andersen, Joshua L
Published in Molecular cancer research (01.02.2024)
Published in Molecular cancer research (01.02.2024)
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Journal Article
SIRT5 IS A DRUGGABLE METABOLIC VULNERABILITY IN ACUTE MYELOID LEUKEMIA
Yan, Dongqing, Franzini, Anca, Pomicter, Anthony D, Halverson, Brayden J, Antelope, Orlando, Mason, Clinton C, Ahmann, Jonathan M, Senina, Anna V, Vellore, Nadeem A, Jones, Courtney L, Zabriskie, Matthew S, Than, Hein, Xiao, Michael J, van Scoyk, Alexandria, Patel, Ami B, Clair, Phillip M, Heaton, William L, Owen, Shawn C, Andersen, Joshua L, Egbert, Christina M, Reisz, Julie A, D'Alessandro, Angelo, Cox, James E, Gantz, Kevin C, Redwine, Hannah M, Iyer, Siddharth M, Khorashad, Jamshid S, Rajabi, Nima, Olsen, Christian A, O'Hare, Thomas, Deininger, Michael W
Published in Blood cancer discovery (01.05.2021)
Published in Blood cancer discovery (01.05.2021)
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TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth
Chan, Tsz-Yin, Egbert, Christina M, Maxson, Julia E, Siddiqui, Adam, Larsen, Logan J, Kohler, Kristina, Balasooriya, Eranga Roshan, Pennington, Katie L, Tsang, Tsz-Ming, Frey, Madison, Soderblom, Erik J, Geng, Huimin, Müschen, Markus, Forostyan, Tetyana V, Free, Savannah, Mercenne, Gaelle, Banks, Courtney J, Valdoz, Jonard, Whatcott, Clifford J, Foulks, Jason M, Bearss, David J, O'Hare, Thomas, Huang, David C S, Christensen, Kenneth A, Moody, James, Warner, Steven L, Tyner, Jeffrey W, Andersen, Joshua L
Published in Nature communications (09.09.2021)
Published in Nature communications (09.09.2021)
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Abstract LB109: A critical role for SIRT5 in acute myeloid leukemia metabolism
Yan, Dongqing, Franzini, Anca, Pomicter, Anthony D., Halverson, Brayden J., Antelope, Orlando, Mason, Clinton C., Ahmann, Jonathan M., Senina, Anna V., Jones, Courtney L. L., Zabriskie, Matthew S., Than, Hein, Xiao, Michael J., van Scoyk, Alexandria, Patel, Ami B., Heaton, William L. L., Owen, Shawn C., Andersen, Joshua L., Egbert, Christina M., Reisz, Julie A., D'Alessandro, Angelo, Cox, James E., Gantz, Kevin C., Redwine, Hannah M., Iyer, Siddharth M., Khorashad, Jamshid S., Rajabi, Nima, Olsen, Christian A., O'Hare, Thomas, Deininger, Michael W.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 3489: TNK1 is a ubiquitin sensing kinase that can be targeted in vivo to block tumor growth
Lopez-Palacios, Tania, Chan, Tsz-Yin, Egbert, Christina M., Ashworth, Spencer, Vaughan, Alec, Forostyan, Tanya V., Siddiqui, Adam, Foulks, Jason M., Moody, James, Maxson, Julia E., Tyner, Jeffrey W., Warner, Steven L., Andersen, Joshua Lyon
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Abstract 1469: 14-3-3 binding during G1 stabilizes and sequesters PTOV1 to the cytoplasm
Pennington, Katie L., McEwan, Colten M., Woods, James, Muir, Colin M., Sahankumari, A G Pramoda, Eastmond, Riley, Balasooriya, Eranga R., Egbert, Christina M., McCormack, Katherine K., Andersen, Joshua L.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Fusion crystallization reveals the behavior of both the 1TEL crystallization chaperone and the TNK1 UBA domain
Nawarathnage, Supeshala, Tseng, Yi Jie, Soleimani, Sara, Smith, Tobin, Romo, Maria J Pedroza, Abiodun, Wisdom Oshireku, Egbert, Christina M, Madhusanka, Deshan, Bunn, Derick, Woods, Bridger, Tsubaki, Evan, Stewart, Cameron, Brown, Seth, Doukov, Tzanko, Andersen, Joshua L, Moody, James D
Published in bioRxiv : the preprint server for biology (14.06.2023)
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Published in bioRxiv : the preprint server for biology (14.06.2023)
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