Coactivator-independent vitamin D receptor signaling causes severe rickets in mice, that is not prevented by a diet high in calcium, phosphate, and lactose
Doms, Stefanie, Verlinden, Lieve, Janssens, Iris, Vanhevel, Justine, Eerlings, Roy, Houtman, René, Kato, Shigeaki, Mathieu, Chantal, Decallonne, Brigitte, Carmeliet, Geert, Verstuyf, Annemieke
Published in Bone Research (20.08.2024)
Published in Bone Research (20.08.2024)
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A disease‐associated missense mutation in CYP4F3 affects the metabolism of leukotriene B4 via disruption of electron transfer
Smeets, Elien, Huang, Shengyun, Lee, Xiao Yin, Van Nieuwenhove, Erika, Helsen, Christine, Handle, Florian, Moris, Lisa, El Kharraz, Sarah, Eerlings, Roy, Devlies, Wout, Willemsen, Mathijs, Bücken, Leoni, Prezzemolo, Teresa, Humblet‐Baron, Stephanie, Voet, Arnout, Rochtus, Anne, Van Schepdael, Ann, Zegher, Francis, Claessens, Frank
Published in Journal of cachexia, sarcopenia and muscle (01.08.2022)
Published in Journal of cachexia, sarcopenia and muscle (01.08.2022)
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Journal Article
Exploiting Ligand-binding Domain Dimerization for Development of Novel Androgen Receptor Inhibitors
Helsen, Christine, Nguyen, Tien T, Lee, Xiao Yin, Eerlings, Roy, Louros, Nikolaos, Schymkowitz, Joost, Rousseau, Frederic, Claessens, Frank, Voet, Arnout
Published in Molecular cancer therapeutics (02.12.2022)
Published in Molecular cancer therapeutics (02.12.2022)
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Cultivation optimization promotes ginsenoside and universal triterpenoid production by engineered yeast
Qiu, Shangkun, Gilani, Mariam Dianat Sabet, Müller, Conrad, Zarazua-Navarro, Roberto-Michael, Liebal, Ulf, Eerlings, Roy, Blank, Lars M.
Published in New biotechnology (25.11.2024)
Published in New biotechnology (25.11.2024)
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Journal Article
Drivers of AR indifferent anti-androgen resistance in prostate cancer cells
Handle, Florian, Prekovic, Stefan, Helsen, Christine, Van den Broeck, Thomas, Smeets, Elien, Moris, Lisa, Eerlings, Roy, Kharraz, Sarah El, Urbanucci, Alfonso, Mills, Ian G., Joniau, Steven, Attard, Gerhardt, Claessens, Frank
Published in Scientific reports (24.09.2019)
Published in Scientific reports (24.09.2019)
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Journal Article
Small-molecule profiling for steroid receptor activity using a universal steroid receptor reporter assay
Eerlings, Roy, Barbakadze, Nana, Nguyen, Tien, Nadaraia, Nanuli, Smeets, Elien, Moris, Lisa, Handle, Florian, El Kharraz, Sarah, Devlies, Wout, Voet, Arnout, Dehaen, Wim, Claessens, Frank, Helsen, Christine
Published in The Journal of steroid biochemistry and molecular biology (01.03.2022)
Published in The Journal of steroid biochemistry and molecular biology (01.03.2022)
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Journal Article
Rational evolution for altering the ligand preference of estrogen receptor alpha
Eerlings, Roy, Gupta, Purvi, Lee, Xiao Yin, Nguyen, Tien, El Kharraz, Sarah, Handle, Florian, Smeets, Elien, Moris, Lisa, Devlies, Wout, Vandewinkel, Bram, Thiry, Irina, Ta, Duy Tien, Gorkovskiy, Anton, Voordeckers, Karin, Henckaerts, Els, Pinheiro, Vitor B., Claessens, Frank, Verstrepen, Kevin J., Voet, Arnout, Helsen, Christine
Published in Protein science (01.04.2024)
Published in Protein science (01.04.2024)
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N/C Interactions Are Dispensable for Normal In Vivo Functioning of the Androgen Receptor in Male Mice
El Kharraz, Sarah, Dubois, Vanessa, Launonen, Kaisa-Mari, Helminen, Laura, Palvimo, Jorma J, Libert, Claude, Smeets, Elien, Moris, Lisa, Eerlings, Roy, Vanderschueren, Dirk, Helsen, Christine, Claessens, Frank
Published in Endocrinology (Philadelphia) (01.09.2022)
Published in Endocrinology (Philadelphia) (01.09.2022)
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Study of novel androgen receptor V770 variant in androgen insensitivity syndrome patients reveals the transitional state of the androgen receptor ligand binding domain homodimer
Helsen, Christine, Rocca, Maria Santa, Nguyen, Tien T., Eerlings, Roy, Lee, Xiao Yin, De Block, Sofie, Vinanzi, Cinzia, Di Millo, Francesco, Giagulli, Vito, Voet, Arnout, Ferlin, Alberto, Claessens, Frank
Published in Protein science (01.04.2023)
Published in Protein science (01.04.2023)
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Journal Article
The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation
El Kharraz, Sarah, Dubois, Vanessa, van Royen, Martin E, Houtsmuller, Adriaan B, Pavlova, Ekatarina, Atanassova, Nina, Nguyen, Tien, Voet, Arnout, Eerlings, Roy, Handle, Florian, Prekovic, Stefan, Smeets, Elien, Moris, Lisa, Devlies, Wout, Ohlsson, Claes, Poutanen, Matti, Verstrepen, Kevin J, Carmeliet, Geert, Launonen, Kaisa-Mari, Helminen, Laura, Palvimo, Jorma J, Libert, Claude, Vanderschueren, Dirk, Helsen, Christine, Claessens, Frank
Published in EMBO reports (06.12.2021)
Published in EMBO reports (06.12.2021)
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Antizyme Inhibitor 1 Regulates Matrikine Expression and Enhances the Metastatic Potential of Aggressive Primary Prostate Cancer
Van den Broeck, Thomas, Moris, Lisa, Gevaert, Thomas, Davicioni, Elai, Boeckx, Bram, Lambrechts, Diether, Helsen, Christine, Handle, Florian, Ghesquière, Bart, Soenen, Stefaan, Smeets, Elien, Eerlings, Roy, El Kharraz, Sarah, Devlies, Wout, Karnes, R Jeffrey, Lotan, Tamara, Van Poppel, Hendrik, Joniau, Steven, Claessens, Frank
Published in Molecular cancer research (01.04.2022)
Published in Molecular cancer research (01.04.2022)
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Journal Article
RF03 | PMON286 Engineering Steroid Receptors to Respond to Chemicals of Choice
Claessens, Frank, Eerlings, Roy, Gupta, Purvi, Lee, Xiao Yin, Kharraz, Sarah E, Jacquemyn, Maarten, Vandewinkel, Bram, Munter, Sofie D, Nguyen, Tien, Handle, Florian, Smeets, Elien, Moris, Lisa, Devlies, Wout, Voordeckers, Karin, Gorkovskiy, Anton, Henckaerts, Els, Daelemans, Dirk, Verstrepen, Kevin J, Voet, Arnout, Helsen, Christine
Published in Journal of the Endocrine Society (01.11.2022)
Published in Journal of the Endocrine Society (01.11.2022)
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