The phospholipase A of Neisseria gonorrhoeae lyses eukaryotic membranes and is necessary for survival in neutrophils and cervical epithelial cells
Apicella, Michael A, Edwards, Jennifer L, Ketterer, Margaret R, Weiss, David S, Zhang, Yuan, Jen, Freda E-C, Jennings, Michael P
Published in mBio (16.10.2024)
Published in mBio (16.10.2024)
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Repurposed Drugs That Block the Gonococcus-Complement Receptor 3 Interaction Can Prevent and Cure Gonococcal Infection of Primary Human Cervical Epithelial Cells
Poole, Jessica, Day, Christopher J, Haselhorst, Thomas, Jen, Freda E-C, Torres, Victor J, Edwards, Jennifer L, Jennings, Michael P
Published in mBio (03.03.2020)
Published in mBio (03.03.2020)
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Analysis of Bacterial Phosphorylcholine-Related Genes Reveals an Association between Type-Specific Biosynthesis Pathways and Biomolecules Targeted for Phosphorylcholine Modification
Zhang, Yuan, Jen, Freda E-C, Edwards, Jennifer L, Jennings, Michael P
Published in Microbiology spectrum (17.08.2023)
Published in Microbiology spectrum (17.08.2023)
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Complement Receptor 3 Mediates HIV-1 Transcytosis across an Intact Cervical Epithelial Cell Barrier: New Insight into HIV Transmission in Women
Day, Christopher J, Hardison, Rachael L, Spillings, Belinda L, Poole, Jessica, Jurcisek, Joseph A, Mak, Johnson, Jennings, Michael P, Edwards, Jennifer L
Published in mBio (22.02.2022)
Published in mBio (22.02.2022)
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Phasevarions mediate random switching of gene expression in pathogenic Neisseria
Srikhanta, Yogitha N, Dowideit, Stefanie J, Edwards, Jennifer L, Falsetta, Megan L, Wu, Hsing-Ju, Harrison, Odile B, Fox, Kate L, Seib, Kate L, Maguire, Tina L, Wang, Andrew H-J, Maiden, Martin C, Grimmond, Sean M, Apicella, Michael A, Jennings, Michael P
Published in PLoS pathogens (01.04.2009)
Published in PLoS pathogens (01.04.2009)
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A laboratory-based predictive pathway for the development of Neisseria gonorrhoeae high-level resistance to corallopyronin A, an inhibitor of bacterial RNA polymerase
Balthazar, Jacqueline T, Golparian, Daniel, Unemo, Magnus, Read, Timothy D, Grosse, Miriam, Stadler, Marc, Pfarr, Kenneth, Schiefer, Andrea, Hoerauf, Achim, Edwards, Jennifer L, Vassylyev, Dmitry G, Shafer, William M
Published in Microbiology spectrum (04.06.2024)
Published in Microbiology spectrum (04.06.2024)
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Journal Article
Erratum for Balthazar et al., “A laboratory-based predictive pathway for the development of Neisseria gonorrhoeae high-level resistance to corallopyronin A, an inhibitor of bacterial RNA polymerase”
Balthazar, Jacqueline T., Golparian, Daniel, Unemo, Magnus, Read, Timothy D., Grosse, Miriam, Stadler, Marc, Pfarr, Kenneth, Schiefer, Andrea, Hoerauf, Achim, Edwards, Jennifer L., Vassylyev, Dmitry G., Shafer, William M.
Published in Microbiology spectrum (01.07.2024)
Published in Microbiology spectrum (01.07.2024)
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Dual pili post-translational modifications synergize to mediate meningococcal adherence to platelet activating factor receptor on human airway cells
Jen, Freda E-C, Warren, Matthew J, Schulz, Benjamin L, Power, Peter M, Swords, W Edward, Weiser, Jeffery N, Apicella, Michael A, Edwards, Jennifer L, Jennings, Michael P
Published in PLoS pathogens (01.05.2013)
Published in PLoS pathogens (01.05.2013)
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The Pathobiology of Neisseria gonorrhoeae Lower Female Genital Tract Infection
Edwards, Jennifer L, Butler, Emily K
Published in Frontiers in cellular and infection microbiology (01.01.2011)
Published in Frontiers in cellular and infection microbiology (01.01.2011)
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Potent In Vitro and Ex Vivo Anti-Gonococcal Activity of the RpoB Inhibitor Corallopyronin A
Edwards, Jennifer L, Balthazar, Jacqueline T, Esposito, Danillo L A, Ayala, Julio C, Schiefer, Andrea, Pfarr, Kenneth, Hoerauf, Achim, Alt, Silke, Hesterkamp, Thomas, Grosse, Miriam, Stadler, Marc, Golparian, Daniel, Unemo, Magnus, Read, Timothy D, Shafer, William M
Published in mSphere (26.10.2022)
Published in mSphere (26.10.2022)
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Phenotypic Characterization of a copA Mutant of Neisseria gonorrhoeae Identifies a Link between Copper and Nitrosative Stress
DJOKO, Karrera Y, FRANIEK, Jessica A, EDWARDS, Jennifer L, FALSETTA, Megan L, KIDD, Stephen P, POTTER, Adam J, CHEN, Nathan H, APICELLA, Michael A, JENNINGS, Michael P, MCEWAN, Alastair G
Published in Infection and Immunity (01.03.2012)
Published in Infection and Immunity (01.03.2012)
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Characterization of an ntrX Mutant of Neisseria gonorrhoeae Reveals a Response Regulator That Controls Expression of Respiratory Enzymes in Oxidase-Positive Proteobacteria
Atack, John M, Srikhanta, Yogitha N, Djoko, Karrera Y, Welch, Jessica P, Hasri, Norain H. M, Steichen, Christopher T, Vanden Hoven, Rachel N, Grimmond, Sean M, Othman, Dk Seti Maimonah Pg, Kappler, Ulrike, Apicella, Michael A, Jennings, Michael P, Edwards, Jennifer L, McEwan, Alastair G
Published in Journal of Bacteriology (01.06.2013)
Published in Journal of Bacteriology (01.06.2013)
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Thioredoxin Reductase Is Essential for Protection of Neisseria gonorrhoeae against Killing by Nitric Oxide and for Bacterial Growth during Interaction with Cervical Epithelial Cells
Potter, Adam J., Kidd, Stephen P., Edwards, Jennifer L., Falsetta, Megan L., Apicella, Michael A., Jennings, Michael P., McEwan, Alastair G.
Published in The Journal of infectious diseases (15.01.2009)
Published in The Journal of infectious diseases (15.01.2009)
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Journal Article
Characterization of the OxyR regulon of Neisseria gonorrhoeae
Seib, Kate L, Wu, Hsing-Ju, Srikhanta, Yogitha N, Edwards, Jennifer L, Falsetta, Megan L, Hamilton, Amanda J, Maguire, Tina L, Grimmond, Sean M, Apicella, Michael A, McEwan, Alastair G, Jennings, Michael P
Published in Molecular microbiology (01.01.2007)
Published in Molecular microbiology (01.01.2007)
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Journal Article
Metal Binding Specificity of the MntABC Permease of Neisseria gonorrhoeae and Its Influence on Bacterial Growth and Interaction with Cervical Epithelial Cells
Lim, Karen H.L, Jones, Christopher E, vanden Hoven, Rachel N, Edwards, Jennifer L, Falsetta, Megan L, Apicella, Michael A, Jennings, Michael P, McEwan, Alastair G
Published in Infection and Immunity (01.08.2008)
Published in Infection and Immunity (01.08.2008)
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Journal Article
Esterase D Is Essential for Protection of Neisseria gonorrhoeae against Nitrosative Stress and for Bacterial Growth during Interaction with Cervical Epithelial Cells
Potter, Adam J., Kidd, Stephen P., Edwards, Jennifer L., Falsetta, Megan L., Apicella, Michael A., Jennings, Michael P., McEwan, Alastair G.
Published in The Journal of infectious diseases (15.07.2009)
Published in The Journal of infectious diseases (15.07.2009)
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