Safety and immunogenicity of SARS-CoV-2 variant mRNA vaccine boosters in healthy adults: an interim analysis
Choi, Angela, Koch, Matthew, Wu, Kai, Chu, Laurence, Ma, LingZhi, Hill, Anna, Nunna, Naveen, Huang, Wenmei, Oestreicher, Judy, Colpitts, Tonya, Bennett, Hamilton, Legault, Holly, Paila, Yamuna, Nestorova, Biliana, Ding, Baoyu, Montefiori, David, Pajon, Rolando, Miller, Jacqueline M., Leav, Brett, Carfi, Andrea, McPhee, Roderick, Edwards, Darin K.
Published in Nature medicine (01.11.2021)
Published in Nature medicine (01.11.2021)
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Serum Neutralizing Activity Elicited by mRNA-1273 Vaccine
Wu, Kai, Werner, Anne P, Koch, Matthew, Choi, Angela, Narayanan, Elisabeth, Stewart-Jones, Guillaume B.E, Colpitts, Tonya, Bennett, Hamilton, Boyoglu-Barnum, Seyhan, Shi, Wei, Moliva, Juan I, Sullivan, Nancy J, Graham, Barney S, Carfi, Andrea, Corbett, Kizzmekia S, Seder, Robert A, Edwards, Darin K
Published in New England Journal of Medicine (15.04.2021)
Published in New England Journal of Medicine (15.04.2021)
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Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains
Ying, Baoling, Whitener, Bradley, VanBlargan, Laura A, Hassan, Ahmed O, Shrihari, Swathi, Liang, Chieh-Yu, Karl, Courtney E, Mackin, Samantha, Chen, Rita E, Kafai, Natasha M, Wilks, Samuel H, Smith, Derek J, Carreño, Juan Manuel, Singh, Gagandeep, Krammer, Florian, Carfi, Andrea, Elbashir, Sayda M, Edwards, Darin K, Thackray, Larissa B, Diamond, Michael S
Published in Science translational medicine (02.02.2022)
Published in Science translational medicine (02.02.2022)
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Three-month antibody persistence of a bivalent Omicron-containing booster vaccine against COVID-19
Chalkias, Spyros, Harper, Charles, Vrbicky, Keith, Walsh, Stephen R., Essink, Brandon, Brosz, Adam, McGhee, Nichole, Tomassini, Joanne E., Chen, Xing, Ying Chang, Sutherland, Andrea, Montefiori, David C., Girard, Bethany, Edwards, Darin K., Jing Feng, Zhou, Honghong, Baden, Lindsey R., Miller, Jacqueline M., Das, Rituparna
Published in Nature communications (23.08.2023)
Published in Nature communications (23.08.2023)
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Interaction dynamics between innate and adaptive immune cells responding to SARS-CoV-2 vaccination in non-human primates
Schramm, Chaim A., Moon, Damee, Peyton, Lowrey, Lima, Noemia S., Wake, Christian, Boswell, Kristin L., Henry, Amy R., Laboune, Farida, Ambrozak, David, Darko, Samuel W., Teng, I-Ting, Foulds, Kathryn E., Carfi, Andrea, Edwards, Darin K., Kwong, Peter D., Koup, Richard A., Seder, Robert A., Douek, Daniel C.
Published in Nature communications (02.12.2023)
Published in Nature communications (02.12.2023)
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Profiling antibody epitopes induced by mRNA-1273 vaccination and boosters
Girard, Bethany, Baum-Jones, Elisabeth, Best, Rebecca L, Campbell, Thomas W, Coupart, Jack, Dangerfield, Kyla, Dhal, Abhilash, Jhatro, Michael, Martinez, Brian, Reifert, Jack, Shon, John, Zhang, Minlu, Waitz, Rebecca, Chalkias, Spyros, Edwards, Darin K, Maglinao, Maha, Paris, Robert, Pajon, Rolando
Published in Frontiers in immunology (18.03.2024)
Published in Frontiers in immunology (18.03.2024)
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A Bivalent Omicron-Containing Booster Vaccine against Covid-19
Chalkias, Spyros, Harper, Charles, Vrbicky, Keith, Walsh, Stephen R., Essink, Brandon, Brosz, Adam, McGhee, Nichole, Tomassini, Joanne E., Chen, Xing, Chang, Ying, Sutherland, Andrea, Montefiori, David C., Girard, Bethany, Edwards, Darin K., Feng, Jing, Zhou, Honghong, Baden, Lindsey R., Miller, Jacqueline M., Das, Rituparna
Published in The New England journal of medicine (06.10.2022)
Published in The New England journal of medicine (06.10.2022)
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Novel approaches for vaccine development
Gebre, Makda S., Brito, Luis A., Tostanoski, Lisa H., Edwards, Darin K., Carfi, Andrea, Barouch, Dan H.
Published in Cell (18.03.2021)
Published in Cell (18.03.2021)
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Safety, immunogenicity and antibody persistence of a bivalent Beta-containing booster vaccine against COVID-19: a phase 2/3 trial
Chalkias, Spyros, Eder, Frank, Essink, Brandon, Khetan, Shishir, Nestorova, Biliana, Feng, Jing, Chen, Xing, Chang, Ying, Zhou, Honghong, Montefiori, David, Edwards, Darin K., Girard, Bethany, Pajon, Rolando, Dutko, Frank J., Leav, Brett, Walsh, Stephen R., Baden, Lindsey R., Miller, Jacqueline M., Das, Rituparna
Published in Nature medicine (01.11.2022)
Published in Nature medicine (01.11.2022)
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Serum Neutralizing Activity of mRNA-1273 against SARS-CoV-2 Variants
Choi, Angela, Koch, Matthew, Wu, Kai, Dixon, Groves, Oestreicher, Judy, Legault, Holly, Stewart-Jones, Guillaume B. E, Colpitts, Tonya, Pajon, Rolando, Bennett, Hamilton, Carfi, Andrea, Edwards, Darin K
Published in Journal of virology (09.11.2021)
Published in Journal of virology (09.11.2021)
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SARS-CoV-2 Omicron Variant Neutralization after mRNA-1273 Booster Vaccination
Pajon, Rolando, Doria-Rose, Nicole A, Shen, Xiaoying, Schmidt, Stephen D, O’Dell, Sijy, McDanal, Charlene, Feng, Wenhong, Tong, Jin, Eaton, Amanda, Maglinao, Maha, Tang, Haili, Manning, Kelly E, Edara, Venkata-Viswanadh, Lai, Lilin, Ellis, Madison, Moore, Kathryn M, Floyd, Katharine, Foster, Stephanie L, Posavad, Christine M, Atmar, Robert L, Lyke, Kirsten E, Zhou, Tongqing, Wang, Lingshu, Zhang, Yi, Gaudinski, Martin R, Black, Walker P, Gordon, Ingelise, Guech, Mercy, Ledgerwood, Julie E, Misasi, John N, Widge, Alicia, Sullivan, Nancy J, Roberts, Paul C, Beigel, John H, Korber, Bette, Baden, Lindsey R, El Sahly, Hana, Chalkias, Spyros, Zhou, Honghong, Feng, Jing, Girard, Bethany, Das, Rituparna, Aunins, Anne, Edwards, Darin K, Suthar, Mehul S, Mascola, John R, Montefiori, David C
Published in New England Journal of Medicine (17.03.2022)
Published in New England Journal of Medicine (17.03.2022)
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Immune response to SARS-CoV-2 after a booster of mRNA-1273: an open-label phase 2 trial
Chu, Laurence, Vrbicky, Keith, Montefiori, David, Huang, Wenmei, Nestorova, Biliana, Chang, Ying, Carfi, Andrea, Edwards, Darin K., Oestreicher, Judy, Legault, Holly, Dutko, Frank J., Girard, Bethany, Pajon, Rolando, Miller, Jacqueline M., Das, Rituparna, Leav, Brett, McPhee, Roderick
Published in Nature medicine (01.05.2022)
Published in Nature medicine (01.05.2022)
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Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant in mice
Scheaffer, Suzanne M., Lee, Diana, Whitener, Bradley, Ying, Baoling, Wu, Kai, Liang, Chieh-Yu, Jani, Hardik, Martin, Philippa, Amato, Nicholas J., Avena, Laura E., Berrueta, Daniela Montes, Schmidt, Stephen D., O’Dell, Sijy, Nasir, Arshan, Chuang, Gwo-Yu, Stewart-Jones, Guillaume, Koup, Richard A., Doria-Rose, Nicole A., Carfi, Andrea, Elbashir, Sayda M., Thackray, Larissa B., Edwards, Darin K., Diamond, Michael S.
Published in Nature medicine (01.01.2023)
Published in Nature medicine (01.01.2023)
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Adjuvant effects of a sequence-engineered mRNA vaccine: translational profiling demonstrates similar human and murine innate response
Edwards, Darin K, Jasny, Edith, Yoon, Heesik, Horscroft, Nigel, Schanen, Brian, Geter, Tanya, Fotin-Mleczek, Mariola, Petsch, Benjamin, Wittman, Vaughan
Published in Journal of translational medicine (03.01.2017)
Published in Journal of translational medicine (03.01.2017)
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Interim Report of the Reactogenicity and Immunogenicity of Severe Acute Respiratory Syndrome Coronavirus 2 XBB–Containing Vaccines
Chalkias, Spyros, McGhee, Nichole, Whatley, Jordan L, Essink, Brandon, Brosz, Adam, Tomassini, Joanne E, Girard, Bethany, Edwards, Darin K, Wu, Kai, Nasir, Arshan, Lee, Diana, Avena, Laura E, Feng, Jing, Deng, Weiping, Montefiori, David C, Baden, Lindsey R, Miller, Jacqueline M, Das, Rituparna
Published in The Journal of infectious diseases (16.08.2024)
Published in The Journal of infectious diseases (16.08.2024)
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Boosting with variant-matched or historical mRNA vaccines protects against Omicron infection in mice
Ying, Baoling, Scheaffer, Suzanne M., Whitener, Bradley, Liang, Chieh-Yu, Dmytrenko, Oleksandr, Mackin, Samantha, Wu, Kai, Lee, Diana, Avena, Laura E., Chong, Zhenlu, Case, James Brett, Ma, LingZhi, Kim, Thu T.M., Sein, Caralyn E., Woods, Angela, Berrueta, Daniela Montes, Chang, Gwo-Yu, Stewart-Jones, Guillaume, Renzi, Isabella, Lai, Yen-Ting, Malinowski, Agata, Carfi, Andrea, Elbashir, Sayda M., Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S.
Published in Cell (28.04.2022)
Published in Cell (28.04.2022)
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Ipsilateral or contralateral boosting of mice with mRNA vaccines confers equivalent immunity and protection against a SARS-CoV-2 Omicron strain
Ying, Baoling, Liang, Chieh-Yu, Desai, Pritesh, Scheaffer, Suzanne M, Elbashir, Sayda M, Edwards, Darin K, Thackray, Larissa B, Diamond, Michael S
Published in Journal of virology (17.09.2024)
Published in Journal of virology (17.09.2024)
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COVID-19 vaccine mRNA-1273 elicits a protective immune profile in mice that is not associated with vaccine-enhanced disease upon SARS-CoV-2 challenge
DiPiazza, Anthony T., Leist, Sarah R., Abiona, Olubukola M., Moliva, Juan I., Werner, Anne, Minai, Mahnaz, Nagata, Bianca M., Bock, Kevin W., Phung, Emily, Schäfer, Alexandra, Dinnon, Kenneth H., Chang, Lauren A., Loomis, Rebecca J., Boyoglu-Barnum, Seyhan, Alvarado, Gabriela S., Sullivan, Nancy J., Edwards, Darin K., Morabito, Kaitlyn M., Mascola, John R., Carfi, Andrea, Corbett, Kizzmekia S., Moore, Ian N., Baric, Ralph S., Graham, Barney S., Ruckwardt, Tracy J.
Published in Immunity (Cambridge, Mass.) (10.08.2021)
Published in Immunity (Cambridge, Mass.) (10.08.2021)
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Original SARS-CoV-2 monovalent and Omicron BA.4/BA.5 bivalent COVID-19 mRNA vaccines: phase 2/3 trial interim results
Chalkias, Spyros, Whatley, Jordan L., Eder, Frank, Essink, Brandon, Khetan, Shishir, Bradley, Paul, Brosz, Adam, McGhee, Nichole, Tomassini, Joanne E., Chen, Xing, Zhao, Xiaoping, Sutherland, Andrea, Shen, Xiaoying, Girard, Bethany, Edwards, Darin K., Feng, Jing, Zhou, Honghong, Walsh, Stephen, Montefiori, David C., Baden, Lindsey R., Miller, Jacqueline M., Das, Rituparna
Published in Nature medicine (01.09.2023)
Published in Nature medicine (01.09.2023)
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