Heterocycle fused cyclohexylglycine derivatives as novel dipeptidyl peptidase-IV inhibitors
Mastracchio, A, Parmee, ER, Leiting, B, Marsilio, F, Patel, R, Thornberry, NA, Weber, AE, Edmondson, SD
Published in Heterocycles (01.01.2004)
Published in Heterocycles (01.01.2004)
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Crystal Structure of Human Phosphodiesterase 3B: Atomic Basis for Substrate and Inhibitor Specificity
Scapin, Giovanna, Patel, Sangita B, Chung, Christine, Varnerin, Jeffrey P, Edmondson, Scott D, Mastracchio, Anthony, Parmee, Emma R, Singh, Suresh B, Becker, Joseph W, Van der Ploeg, Lex H. T, Tota, Michael R
Published in Biochemistry (Easton) (25.05.2004)
Published in Biochemistry (Easton) (25.05.2004)
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The Total Synthesis of Spirotryprostatin A
Edmondson, Scott D., Danishefsky, Samuel J.
Published in Angewandte Chemie International Edition (04.05.1998)
Published in Angewandte Chemie International Edition (04.05.1998)
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Discovery of potent and selective orally bioavailable β-substituted phenylalanine derived dipeptidyl peptidase IV inhibitors
Edmondson, Scott D., Mastracchio, Anthony, Duffy, Joseph L., Eiermann, George J., He, Huaibing, Ita, Ida, Leiting, Barbara, Leone, Joseph F., Lyons, Kathryn A., Makarewicz, Amanda M., Patel, Reshma A., Petrov, Aleksandr, Wu, Joseph K., Thornberry, Nancy A., Weber, Ann E.
Published in Bioorganic & medicinal chemistry letters (15.06.2005)
Published in Bioorganic & medicinal chemistry letters (15.06.2005)
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Potent and selective proline derived dipeptidyl peptidase IV inhibitors
Edmondson, Scott D., Mastracchio, Anthony, Beconi, Maria, Colwell, Lawrence F., Habulihaz, Bahanu, He, Huaibing, Kumar, Sanjeev, Leiting, Barbara, Lyons, Kathryn A., Mao, Ann, Marsilio, Frank, Patel, Reshma A., Wu, Joseph K., Zhu, Lan, Thornberry, Nancy A., Weber, Ann E., Parmee, Emma R.
Published in Bioorganic & medicinal chemistry letters (18.10.2004)
Published in Bioorganic & medicinal chemistry letters (18.10.2004)
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Journal Article
4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors
Parmee, Emma R., He, Jiafang, Mastracchio, Anthony, Edmondson, Scott D., Colwell, Larry, Eiermann, George, Feeney, William P., Habulihaz, Bahanu, He, Huaibing, Kilburn, Ruth, Leiting, Barbara, Lyons, Kathryn, Marsilio, Frank, Patel, Reshma A., Petrov, Aleksandr, Di Salvo, Jerry, Wu, Joseph K., Thornberry, Nancy A., Weber, Ann E.
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
Published in Bioorganic & medicinal chemistry letters (05.01.2004)
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Benzyl vinylogous amide substituted aryldihydropyridazinones and aryldimethylpyrazolones as potent and selective PDE3B inhibitors
Edmondson, Scott D., Mastracchio, Anthony, He, Jiafang, Chung, Christine C., Forrest, Michael J., Hofsess, Scott, MacIntyre, Euan, Metzger, Joseph, O'Connor, Naphtali, Patel, Kajal, Tong, Xinchun, Tota, Michael R., Van der Ploeg, Lex H.T., Varnerin, Jeff P., Fisher, Michael H., Wyvratt, Matthew J., Weber, Ann E., Parmee, Emma R.
Published in Bioorganic & medicinal chemistry letters (17.11.2003)
Published in Bioorganic & medicinal chemistry letters (17.11.2003)
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Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors
Xu, Jinyou, Wei, Lan, Mathvink, Robert, Edmondson, Scott D., Mastracchio, Anthony, Eiermann, George J., He, Huaibing, Leone, Joseph F., Leiting, Barbara, Lyons, Kathryn A., Marsilio, Frank, Patel, Reshma A., Petrov, Aleksandr, Wu, Joseph K., Thornberry, Nancy A., Weber, Ann E.
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
Published in Bioorganic & medicinal chemistry letters (01.03.2006)
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Crystallization and preliminary X-ray diffraction analysis of the catalytic domain of recombinant human phosphodiesterase 3B
Patel, Sangita B., Varnerin, Jeffrey P., Tota, Michael R., Edmondson, Scott D., Parmee, Emma R., Becker, Joseph W., Scapin, Giovanna
Published in Acta crystallographica. Section D, Biological crystallography. (01.01.2004)
Published in Acta crystallographica. Section D, Biological crystallography. (01.01.2004)
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Studies Directed toward the Synthesis of the Unusual Antileukemic Diterpene Jatrophatrione. 1. A Solution to the Problem of Chirality Merger during Elaboration of the Entire Carbotricyclic Framework
Paquette, Leo A, Nakatani, Shogo, Zydowsky, Thomas M, Edmondson, Scott D, Sun, Li-Qiang, Skerlj, Renato
Published in Journal of organic chemistry (30.04.1999)
Published in Journal of organic chemistry (30.04.1999)
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Studies Directed toward the Synthesis of the Unusual Antileukemic Diterpene Jatrophatrione. 2. Functionalization of Advanced Polycyclic Precursors to the 9-Epi and 8,9-Dehydro Congeners
Paquette, Leo A, Edmondson, Scott D, Monck, Nathaniel, Rogers, Robin D
Published in Journal of organic chemistry (30.04.1999)
Published in Journal of organic chemistry (30.04.1999)
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Journal Article
A concise route to the tetracyclic core of phorbol
Paquette, Leo A., Sauer, Daryl R., Edmondson, Scott D., Friedrich, Dirk
Published in Tetrahedron (04.04.1994)
Published in Tetrahedron (04.04.1994)
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Conformational Analysis of Poly(spirotetrahydrofuranyl)cyclohexyl Systems. The Preference of Multiple C−O Bonds for Equatorial Occupancy
Paquette, Leo A, Stepanian, Marshall, Branan, Bruce M, Edmondson, Scott D, Bauer, Cary B, Rogers, Robin D
Published in Journal of the American Chemical Society (08.05.1996)
Published in Journal of the American Chemical Society (08.05.1996)
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Analysis of the Conformational Nature, Resolvability, and Thermal Racemization of Hetero 2,3-Dispiro Cyclohexanones. The Weighting of Carbonyl/C-X Stabilization Relative to the Electronic Interaction between the Vicinal Electronegative Substituents
Paquette, Leo A, Branan, Bruce M, Friedrich, Dirk, Edmondson, Scott D, Rogers, Robin D
Published in Journal of the American Chemical Society (01.01.1994)
Published in Journal of the American Chemical Society (01.01.1994)
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