Genistein improves neuropathology and corrects behaviour in a mouse model of neurodegenerative metabolic disease
Malinowska, Marcelina, Wilkinson, Fiona L, Langford-Smith, Kia J, Langford-Smith, Alex, Brown, Jillian R, Crawford, Brett E, Vanier, Marie T, Grynkiewicz, Grzegorz, Wynn, Rob F, Wraith, J Ed, Wegrzyn, Grzegorz, Bigger, Brian W
Published in PloS one (01.12.2010)
Published in PloS one (01.12.2010)
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Neuropathology in mouse models of mucopolysaccharidosis type I, IIIA and IIIB
Wilkinson, Fiona L, Holley, Rebecca J, Langford-Smith, Kia J, Badrinath, Soumya, Liao, Aiyin, Langford-Smith, Alex, Cooper, Jonathan D, Jones, Simon A, Wraith, J Ed, Wynn, Rob F, Merry, Catherine L R, Bigger, Brian W
Published in PloS one (27.04.2012)
Published in PloS one (27.04.2012)
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A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow
Wynn, Robert F., Hart, Claire A., Corradi-Perini, Carla, O'Neill, Liam, Evans, Caroline A., Wraith, J. Ed, Fairbairn, Leslie J., Bellantuono, Ilaria
Published in Blood (01.11.2004)
Published in Blood (01.11.2004)
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Improved Metabolic Correction in Patients with Lysosomal Storage Disease Treated with Hematopoietic Stem Cell Transplant Compared with Enzyme Replacement Therapy
Wynn, Robert F., MD, Wraith, J. Ed, FRCPCH, Mercer, Jean, O'Meara, Anne, FRCPI, Tylee, Karen, BSc, Thornley, Margaret, Church, Heather J., PhD, Bigger, Brian W., PhD
Published in The Journal of pediatrics (01.04.2009)
Published in The Journal of pediatrics (01.04.2009)
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Journal Article
Hematopoietic stem cell transplantation improves the high incidence of neutralizing allo-antibodies observed in Hurler’s syndrome after pharmacological enzyme replacement therapy
AMEER SAIF, Muhammad, BIGGER, Brian W, BROOKES, Karen E, MERCER, Jean, TYLEE, Karen L, CHURCH, Heather J, BONNEY, Denise K, JONES, Simon, ED WRAITH, J, WYNN, Robert F
Published in Haematologica (Roma) (01.09.2012)
Published in Haematologica (Roma) (01.09.2012)
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Journal Article
Signal one and two blockade are both critical for non-myeloablative murine HSCT across a major histocompatibility complex barrier
Langford-Smith, Kia J, Sandiford, Zara, Langford-Smith, Alex, Wilkinson, Fiona L, Jones, Simon A, Wraith, J Ed, Wynn, Robert F, Bigger, Brian W
Published in PloS one (17.10.2013)
Published in PloS one (17.10.2013)
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Journal Article
Heparin cofactor II-thrombin complex and dermatan sulphate:chondroitin sulphate ratio are biomarkers of short- and long-term treatment effects in mucopolysaccharide diseases
Langford-Smith, Kia Jane, Mercer, Jean, Petty, June, Tylee, Karen, Church, Heather, Roberts, Jane, Moss, Gill, Jones, Simon, Wynn, Rob, Wraith, J. Ed, Bigger, Brian W.
Published in Journal of inherited metabolic disease (01.04.2011)
Published in Journal of inherited metabolic disease (01.04.2011)
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Journal Article
Enzyme Replacement Therapy for Mucopolysaccharidoses: Opinions of Patients and Families
Coman, David J., FRACP, Hayes, Ian M., FRACP, Collins, Veronica, PhD, Sahhar, Margaret, MSW, Wraith, J. Ed, FRCPCH, Delatycki, Martin B., FRACP, PhD
Published in The Journal of pediatrics (01.05.2008)
Published in The Journal of pediatrics (01.05.2008)
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Journal Article
High dose genistein in Sanfilippo syndrome: A randomised controlled trial
Ghosh, Arunabha, Rust, Stewart, Langford‐Smith, Kia, Weisberg, Daniel, Canal, Maria, Breen, Catherine, Hepburn, Michelle, Tylee, Karen, Vaz, Frédéric M., Vail, Andy, Wijburg, Frits, O'Leary, Claire, Parker, Helen, Wraith, J. Ed, Bigger, Brian W., Jones, Simon A.
Published in Journal of inherited metabolic disease (01.09.2021)
Published in Journal of inherited metabolic disease (01.09.2021)
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Journal Article
Retrovirally mediated correction of bone marrow–derived mesenchymal stem cells from patients with mucopolysaccharidosis type I
Baxter, Melissa A., Wynn, Robert F., Deakin, Jonathan A., Bellantuono, Ilaria, Edington, Kirsten G., Cooper, Alan, Besley, Guy T.N., Church, Heather J., Wraith, J. Ed, Carr, Trevor F., Fairbairn, Leslie J.
Published in Blood (01.03.2002)
Published in Blood (01.03.2002)
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Journal Article
Genistein reduces lysosomal storage in peripheral tissues of mucopolysaccharide IIIB mice
Malinowska, Marcelina, Wilkinson, Fiona L., Bennett, William, Langford-Smith, Kia J., O’Leary, H. Angharad, Jakobkiewicz-Banecka, Joanna, Wynn, Rob, Wraith, J. Ed, Wegrzyn, Grzegorz, Bigger, Brian W.
Published in Molecular genetics and metabolism (01.11.2009)
Published in Molecular genetics and metabolism (01.11.2009)
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Journal Article
Evaluation of heparin cofactor II–thrombin complex as a biomarker on blood spots from mucopolysaccharidosis I, IIIA and IIIB mice
Langford-Smith, Kia, Arasaradnam, Malani, Wraith, J. Ed, Wynn, Rob, Bigger, Brian W.
Published in Molecular genetics and metabolism (01.03.2010)
Published in Molecular genetics and metabolism (01.03.2010)
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Journal Article
Enzyme Replacement Therapy and Extended Newborn Screening for Mucopolysaccharidoses: Opinions of Treating Physicians
Coman, David J., Hayes, Ian M., Collins, Veronica, Sahhar, Margaret, Wraith, J. Ed, Delatycki, Martin B.
Published in JIMD Reports - Case and Research Reports, 2011/1 (01.01.2011)
Published in JIMD Reports - Case and Research Reports, 2011/1 (01.01.2011)
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Book Chapter
Journal Article
Refsum disease is caused by mutations in the phytanoyl-CoA hydroxylase gene
Jansen, Gerbert A, Oftnan, Rob, Ferdinandusse, Sacha, Ijlst, Lodewijk, Muijsers, Anton O, Skjeldal, Ola H, Stokke, Oddvar, Jakobs, Cornells, Besley, Guy T.N, Wraith, J. Ed, Wanders, Ronald J.A
Published in Nature genetics (01.10.1997)
Published in Nature genetics (01.10.1997)
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