Multifunctional Effects of a Small-Molecule STAT3 Inhibitor on NASH and Hepatocellular Carcinoma in Mice
Jung, Kwang Hwa, Yoo, Wonbeak, Stevenson, Heather L, Deshpande, Dipti, Shen, Hong, Gagea, Mihai, Yoo, Suk-Young, Wang, Jing, Eckols, T Kris, Bharadwaj, Uddalak, Tweardy, David J, Beretta, Laura
Published in Clinical cancer research (15.09.2017)
Published in Clinical cancer research (15.09.2017)
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Journal Article
Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma
Bharadwaj, Uddalak, Eckols, T Kris, Xu, Xuejun, Kasembeli, Moses M, Chen, Yunyun, Adachi, Makoto, Song, Yongcheng, Mo, Qianxing, Lai, Stephen Y, Tweardy, David J
Published in Oncotarget (03.05.2016)
Published in Oncotarget (03.05.2016)
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Journal Article
Modulation of STAT3 folding and function by TRiC/CCT chaperonin
Kasembeli, Moses, Lau, Wilson Chun Yu, Roh, Soung-Hun, Eckols, T Kris, Frydman, Judith, Chiu, Wah, Tweardy, David J
Published in PLoS biology (01.04.2014)
Published in PLoS biology (01.04.2014)
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Journal Article
Small-molecule targeting of signal transducer and activator of transcription (STAT) 3 to treat non-small cell lung cancer
Lewis, Katherine M, Bharadwaj, Uddalak, Eckols, T. Kris, Kolosov, Mikhail, Kasembeli, Moses M, Fridley, Colleen, Siller, Ricardo, Tweardy, David J
Published in Lung cancer (Amsterdam, Netherlands) (01.11.2015)
Published in Lung cancer (Amsterdam, Netherlands) (01.11.2015)
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Journal Article
Synthetic and Biological Studies of Phaeosphaerides
Chatzimpaloglou, Anthoula, Kolosov, Mikhail, Eckols, T. Kris, Tweardy, David J, Sarli, Vasiliki
Published in Journal of organic chemistry (02.05.2014)
Published in Journal of organic chemistry (02.05.2014)
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Journal Article
Combined Inhibition of STAT3 and DNA Repair in Palbociclib-Resistant ER-Positive Breast Cancer
Kettner, Nicole M, Vijayaraghavan, Smruthi, Durak, Merih Guray, Bui, Tuyen, Kohansal, Mehrnoosh, Ha, Min Jin, Liu, Bin, Rao, Xiayu, Wang, Jing, Yi, Min, Carey, Jason P W, Chen, Xian, Eckols, T Kris, Raghavendra, Akshara S, Ibrahim, Nuhad K, Karuturi, Meghan Sri, Watowich, Stephanie S, Sahin, Aysegul, Tweardy, David J, Hunt, Kelly K, Tripathy, Debu, Keyomarsi, Khandan
Published in Clinical cancer research (01.07.2019)
Published in Clinical cancer research (01.07.2019)
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Journal Article
Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance
Eckols, Kris T., Engineer, Nikita, Bharadwaj, Uddalak, Kasembeli, Moses, Robinson, Prema, Tweardy, David J.
Published in BioMed research international (01.01.2016)
Published in BioMed research international (01.01.2016)
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Journal Article
Novel STAT3 small-molecule inhibitors identified by structure-based virtual ligand screening incorporating SH2 domain flexibility
Kong, Ren, Bharadwaj, Uddalak, Eckols, T. Kris, Kolosov, Mikhail, Wu, Haoyi, Cruz-Pavlovich, Francisco J. Santa, Shaw, Alison, Ifelayo, Oluwatomilona I., Zhao, Hong, Kasembeli, Moses M., Wong, Stephen T.C., Tweardy, David J.
Published in Pharmacological research (01.07.2021)
Published in Pharmacological research (01.07.2021)
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Journal Article
Correction: Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma
Bharadwaj, Uddalak, Eckols, T Kris, Xu, Xuejun, Kasembeli, Moses M, Chen, Yunyun, Adachi, Makoto, Song, Yongcheng, Mo, Qianxing, Lai, Stephen Y, Tweardy, David J
Published in Oncotarget (22.02.2019)
Published in Oncotarget (22.02.2019)
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Journal Article
Monoclonal Antibodies Specific for STAT3β Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer
Bharadwaj, Uddalak, Kasembeli, Moses M, Eckols, T Kris, Kolosov, Mikhail, Lang, Paul, Christensen, Kurt, Edwards, Dean P, Tweardy, David J
Published in Cancers (29.09.2014)
Published in Cancers (29.09.2014)
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Journal Article
Substance P is required for the pathogenesis of EMCV infection in mice
Robinson, Prema, Garza, Armandina, Moore, Jeffrey, Eckols, T Kris, Parti, Skakun, Balaji, Vishwanathan, Vallejo, Jesus, Tweardy, David J
Published in International journal of clinical and experimental medicine (01.01.2009)
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Published in International journal of clinical and experimental medicine (01.01.2009)
Journal Article
Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer
Bharadwaj, U, Eckols, T K, Kolosov, M, Kasembeli, M M, Adam, A, Torres, D, Zhang, X, Dobrolecki, L E, Wei, W, Lewis, M T, Dave, B, Chang, J C, Landis, M D, Creighton, C J, Mancini, M A, Tweardy, D J
Published in Oncogene (12.03.2015)
Published in Oncogene (12.03.2015)
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Journal Article
Abstract P6-04-12: STAT3 as a therapeutic target in estrogen receptor positive breast cancer patients refractory to CDK4/6 inhibition
Kettner, Nicole M, Bui, Tuyen, Ha, Min Jin, Eckols, T Kris, Tweardy, David J, Meric-Bernstam, Funda, Hunt, Kelly K, Tripathy, Debu, Keyomarsi, Khandan
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Journal Article
ChemInform Abstract: Synthetic and Biological Studies of Phaeosphaerides
Chatzimpaloglou, Anthoula, Kolosov, Mikhail, Eckols, T. Kris, Tweardy, David J., Sarli, Vasiliki
Published in ChemInform (30.09.2014)
Published in ChemInform (30.09.2014)
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Journal Article
Abstract 323: Combined inhibition of STAT-3 & DNA repair in palbociclib resistant breast cancer
Kettner, Nicole M., Vijayaraghavan, Smruthi, Durak, Merih Guray, Bui, Tuyen, Kohansal, Mehrnoosh, Ha, Min Jin, Liu, Bin, Rao, Xiayu, Yang, Jing, Yi, Min, Carey, Jason P., Chen, Xian, Eckols, T. Kris, Raghavendra, Akshara S., Ibrahim, Nuhad K., Karuturi, Meghan, Watowich, Stephanie S., Sahin, Aysegul A., Tweardy, David J., Hunt, Kelly K., Tripathy, Debu, Keyomarsi, Khandan
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 1774: Circulating IL-6, an early biomarker in HR-positive, HER2-negative metastatic breast cancer patients progressing on CDK4/6 inhibitors
Kettner, Nicole M., Bui, Tuyen N., Navarro-Yepes, Juliana, Eckols, T Kris, Raghavendra, Akshara S., Tweardy, David J., Hunt, Kelly K., Tripathy, Debu, Keyomarsi, Khandan
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Abstract 2095: Selective inhibition of the STAT3 pathway suppresses K-ras mutant lung tumorigenesis
Clowers, Michael J., Chou, Cody, Yuan, Bo, Velasco, Walter V., Zarghooni, Melody, Peng, Stephen, Eckols, T Kris, Kadara, Humam, Tweardy, David J., Moghaddam, Seyed Javad
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Multi-functional effects of a small-molecule STAT3 inhibitor on NASH and HCC in mice
Jung, Kwang Hwa, Yoo, Wonbeak, Stevenson, Heather L., Deshpande, Dipti, Shen, Hong, Gagea, Mihai, Yoo, Suk-Young, Wang, Jing, Eckols, T. Kris, Bharadwaj, Uddalak, Tweardy, David J., Beretta, Laura
Published in Clinical cancer research (22.05.2017)
Published in Clinical cancer research (22.05.2017)
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Journal Article
Modulation of STAT3 Folding and Function by TRiC/CCT Chaperonin: e1001844
Kasembeli, Moses, Lau, Wilson ChunYu, Roh, Soung-Hun, Eckols, T Kris, Frydman, Judith, Chiu, Wah, Tweardy, David J
Published in PLoS biology (01.04.2014)
Published in PLoS biology (01.04.2014)
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Journal Article
Monoclonal Antibodies Specific for STAT3[beta] Reveal Its Contribution to Constitutive STAT3 Phosphorylation in Breast Cancer
Bharadwaj, Uddalak, Kasembeli, Moses M, Eckols, T Kris, Kolosov, Mikhail, Lang, Paul, Christensen, Kurt, Edwards, Dean P, Tweardy, David J
Published in Cancers (01.12.2014)
Published in Cancers (01.12.2014)
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Journal Article