Population pharmacokinetics and exposure‐response analyses for efficacy and safety of upadacitinib in patients with axial spondyloarthritis
Bhatnagar, Sumit, Eckert, Doerthe, Stodtmann, Sven, Song, In‐Ho, Wung, Peter, Liu, Wei, Mohamed, Mohamed‐Eslam F.
Published in Clinical and translational science (01.02.2024)
Published in Clinical and translational science (01.02.2024)
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Population Pharmacokinetics of Glecaprevir/Pibrentasvir in HCV-infected Japanese Subjects in Phase 3 CERTAIN-1 and CERTAIN-2 Trials
Suleiman, Ahmed Abbas, Lin, Chih-Wei, Liu, Wei, Eckert, Doerthe, Mensing, Sven, Burroughs, Margaret, Kato, Koji, Chayama, Kazuaki, Kumada, Hiromitsu, Oberoi, Rajneet K
Published in Journal of clinical pharmacology (01.03.2020)
Published in Journal of clinical pharmacology (01.03.2020)
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43131 Population Pharmacokinetic and Pharmacodynamic Analyses of Cedirogant in Healthy Subjects and Subjects with Moderate to Severe Psoriasis
Maier, Corinna, Eckert, Doerthe, Laroux, Stephen, Hew, Kinjal M., Suleiman, Ahmed, Liu, Wei, Mohamed, Mohamed-Eslam F.
Published in Journal of the American Academy of Dermatology (01.09.2023)
Published in Journal of the American Academy of Dermatology (01.09.2023)
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Journal Article
Pharmacokinetics and Exposure–Response Analyses to Support Dose Selection of Upadacitinib in Crohn's Disease
Bhatnagar, Sumit, Schlachter, Louisa, Eckert, Doerthe, Stodtmann, Sven, Liu, Wei, Lacerda, Ana P., Mohamed, Mohamed‐Eslam F.
Published in Clinical pharmacology and therapeutics (01.11.2024)
Published in Clinical pharmacology and therapeutics (01.11.2024)
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Journal Article
Extrapolation of Upadacitinib Efficacy in Juvenile Idiopathic Arthritis Leveraging Pharmacokinetics, Exposure-Response Models, and Real-World Patient Data
Qian, Yuli, Schlachter, Louisa, Eckert, Doerthe, Stodtmann, Sven, Shmagel, Anna, Peng, Yi, Liu, Wei, Mohamed, Mohamed-Eslam F
Published in Clinical pharmacology and therapeutics (29.09.2024)
Published in Clinical pharmacology and therapeutics (29.09.2024)
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Pharmacokinetics of Risankizumab in Asian Healthy Subjects and Patients With Moderate to Severe Plaque Psoriasis, Generalized Pustular Psoriasis, and Erythrodermic Psoriasis
Khatri, Amit, Eckert, Doerthe, Oberoi, Rajneet, Suleiman, Ahmed, Pang, Yinuo, Cheng, Ling, Othman, Ahmed A.
Published in Journal of clinical pharmacology (01.12.2019)
Published in Journal of clinical pharmacology (01.12.2019)
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Journal Article
Population pharmacokinetic and exposure-response modelling to inform upadacitinib dose selection in adolescent and adult patients with atopic dermatitis
Ismail, Mohamed, Doelger, Eva, Eckert, Doerthe, Irvine, Alan D, Chu, Alvina D, Teixeira, Henrique D, Liu, Wei, Nader, Ahmed
Published in British journal of clinical pharmacology (01.10.2023)
Published in British journal of clinical pharmacology (01.10.2023)
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Exposure-Response Model With Time-Varying Predictors to Estimate the Effects of Veliparib in Combination With Carboplatin/Paclitaxel and as Monotherapy: Veliparib Phase 3 Study in BRCA-Mutated Advanced Breast Cancer (BROCADE3) Trial
Stodtmann, Sven, Eckert, Doerthe, Joshi, Rujuta, Nuthalapati, Silpa, Ratajczak, Christine K, Menon, Rajeev, Mensing, Sven, Xiong, Hao
Published in Journal of clinical pharmacology (01.10.2022)
Published in Journal of clinical pharmacology (01.10.2022)
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Journal Article
Upadacitinib Population Pharmacokinetics and Exposure-Response Relationships in Ulcerative Colitis Patients
Ponce-Bobadilla, Ana Victoria, Stodtmann, Sven, Eckert, Doerthe, Zhou, Wen, Liu, Wei, Mohamed, Mohamed-Eslam F.
Published in Clinical pharmacokinetics (01.01.2023)
Published in Clinical pharmacokinetics (01.01.2023)
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Journal Article
Impact of Venetoclax Exposure on Clinical Efficacy and Safety in Biomarker-Selected Patients with Relapsed or Refractory Multiple Myeloma: Implication for Dose Selection
Badawi, Mohamed A, Coppola, Sheryl, Eckert, Doerthe, Gopalakrishnan, Sathej, Doelger, Eva, Dobkowska, Edyta, Kumar, Shaji K, Huang, Weize, Menon, Rajeev, Salem, Ahmed Hamed
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
A Population Pharmacokinetic Meta‐Analysis of Veliparib, a PARP Inhibitor, Across Phase 1/2/3 Trials in Cancer Patients
Stodtmann, Sven, Nuthalapati, Silpa, Eckert, Doerthe, Kasichayanula, Sreeneeranj, Joshi, Rujuta, Bach, Bruce A., Mensing, Sven, Menon, Rajeev, Xiong, Hao
Published in Journal of clinical pharmacology (01.09.2021)
Published in Journal of clinical pharmacology (01.09.2021)
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Journal Article
Impact of Venetoclax Exposure on Clinical Efficacy and Safety in Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia
Freise, Kevin J., Jones, Aksana K., Eckert, Doerthe, Mensing, Sven, Wong, Shekman L., Humerickhouse, Rod A., Awni, Walid M., Salem, Ahmed Hamed
Published in Clinical pharmacokinetics (01.05.2017)
Published in Clinical pharmacokinetics (01.05.2017)
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Journal Article
Pharmacokinetics and exposure-efficacy relationship of adalimumab in pediatric patients with moderate to severe Crohn's disease: results from a randomized, multicenter, phase-3 study
Sharma, Shringi, Eckert, Doerthe, Hyams, Jeffrey S, Mensing, Sven, Thakkar, Roopal B, Robinson, Anne M, Rosh, Joel R, Ruemmele, Frank M, Awni, Walid M
Published in Inflammatory bowel diseases (01.04.2015)
Published in Inflammatory bowel diseases (01.04.2015)
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Journal Article
Venetoclax Exposure-Efficacy and Exposure-Safety Relationships in Subjects with Treatment-Naïve Acute Myeloid Leukemia Who Are Ineligible for Intensive Chemotherapy
Eckert, Doerthe, Brackman, Deanna, Menon, Rajeev, Salem, Ahmed Hamed, Potluri, Jalaja, Smith, B. Douglas, Wei, Andrew H., Hayslip, John, Miles, Dale, Mensing, Sven, Gopalakrishnan, Sathej, Zha, Jiuhong
Published in Blood (05.11.2020)
Published in Blood (05.11.2020)
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Journal Article
Venetoclax exposure‐efficacy and exposure‐safety relationships in patients with treatment‐naïve acute myeloid leukemia who are ineligible for intensive chemotherapy
Brackman, Deanna, Eckert, Doerthe, Menon, Rajeev, Salem, Ahmed Hamed, Potluri, Jalaja, Smith, B. Douglas, Wei, Andrew H., Hayslip, John, Miles, Dale, Mensing, Sven, Gopalakrishnan, Sathej, Zha, Jiuhong
Published in Hematological oncology (01.04.2022)
Published in Hematological oncology (01.04.2022)
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Journal Article
Venetoclax in biomarker‐selected multiple myeloma patients: Impact of exposure on clinical efficacy and safety
Badawi, Mohamed, Coppola, Sheryl, Eckert, Doerthe, Gopalakrishnan, Sathej, Engelhardt, Benjamin, Doelger, Eva, Huang, Weize, Dobkowska, Edyta, Kumar, Shaji, Menon, Rajeev M., Salem, Ahmed Hamed
Published in Hematological oncology (01.01.2024)
Published in Hematological oncology (01.01.2024)
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Journal Article
Population pharmacokinetics and exposure-response analyses for efficacy and safety of apadacitinib in patients with axial Spondyloarthritis
Bhatnagar, Sumit, Eckert, Doerthe, Stodtmann, Sven, Song, In-Ho, Wung, Peter, Liu, Wei, Mohamed, Mohamed-Eslam F
Published in Clinical and translational science (01.02.2024)
Published in Clinical and translational science (01.02.2024)
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Journal Article
Tu1733 UPADACITINIB PHARMACOKINETIC AND EXPOSURE-RESPONSE RELATIONSHIPS IN SUBJECTS WITH CROHN'S DISEASE - ANALYSES OF PHASE 3 STUDIES
Bhatnagar, Sumit, Schlacter, Louisa, Eckert, Doerthe, Stodtmann, Sven, Liu, Wei, Lacerda, Ana P., Mohamed, Mohamed-Eslam F.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2023)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2023)
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Journal Article
Population pharmacokinetics of paritaprevir, ombitasvir, dasabuvir, ritonavir and ribavirin in hepatitis C virus genotype 1 infection: analysis of six phase III trials
Mensing, Sven, Eckert, Doerthe, Sharma, Shringi, Polepally, Akshanth R., Khatri, Amit, Podsadecki, Thomas J., Awni, Walid M., Menon, Rajeev M., Dutta, Sandeep
Published in British journal of clinical pharmacology (01.03.2017)
Published in British journal of clinical pharmacology (01.03.2017)
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Journal Article
Cedirogant Population Pharmacokinetics and Pharmacodynamic Analyses of Interleukin-17A Inhibition in Two Phase 1 Studies in Healthy Participants and Participants with Moderate to Severe Psoriasis
Maier, Corinna S, Eckert, Doerthe, Laroux, F Stephen, Hew, Kinjal M, Suleiman, Ahmed A, Liu, Wei, Mohamed, Mohamed-Eslam F
Published in Clinical pharmacology in drug development (01.05.2024)
Published in Clinical pharmacology in drug development (01.05.2024)
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