Stromal-derived interleukin 6 drives epithelial-to-mesenchymal transition and therapy resistance in esophageal adenocarcinoma
Ebbing, Eva A., van der Zalm, Amber P., Steins, Anne, Creemers, Aafke, Hermsen, Simone, Rentenaar, Rosa, Klein, Michelle, Waasdorp, Cynthia, Hooijer, Gerrit K. J., Meijer, Sybren L., Krishnadath, Kausilia K., Punt, Cornelis J. A., van Berge Henegouwen, Mark I., Gisbertz, Suzanne S., van Delden, Otto M., Hulshof, Maarten C. C. M., Medema, Jan Paul, van Laarhoven, Hanneke W. M., Bijlsma, Maarten F.
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.02.2019)
Get full text
Journal Article
A systematic review and meta-analysis of prognostic biomarkers in resectable esophageal adenocarcinomas
Creemers, Aafke, Ebbing, Eva A., Pelgrim, Thomas C., Lagarde, Sjoerd M., van Etten-Jamaludin, Faridi S., van Berge Henegouwen, Mark I., Hulshof, Maarten C. C. M., Krishnadath, Kausilia K., Meijer, Sybren L., Bijlsma, Maarten F., van Oijen, Martijn G. H., van Laarhoven, Hanneke W. M.
Published in Scientific reports (05.09.2018)
Published in Scientific reports (05.09.2018)
Get full text
Journal Article
Rapid stromal remodeling by short‐term VEGFR2 inhibition increases chemotherapy delivery in esophagogastric adenocarcinoma
Steins, Anne, Klaassen, Remy, Jacobs, Igor, Schabel, Matthias C., Lier, Monique G. J. T. B., Ebbing, Eva A., Hectors, Stefanie J., Tas, Sander W., Maracle, Chrissta X., Punt, Cornelis J. A., Siebes, Maria, Bergman, Jacques J. G. H. M., Medema, Jan Paul, Wilmink, Johanna W., Mathot, Ron A. A., Strijkers, Gustav J., Bijlsma, Maarten F., Laarhoven, Hanneke W. M.
Published in Molecular oncology (01.04.2020)
Published in Molecular oncology (01.04.2020)
Get full text
Journal Article
The pluripotency factor NANOG contributes to mesenchymal plasticity and is predictive for outcome in esophageal adenocarcinoma
van der Zalm, Amber P., Dings, Mark P. G., Manoukian, Paul, Boersma, Hannah, Janssen, Reimer, Bailey, Peter, Koster, Jan, Zwijnenburg, Danny, Volckmann, Richard, Bootsma, Sanne, Waasdorp, Cynthia, van Mourik, Monique, Blangé, Dionne, van den Ende, Tom, Oyarce, César I., Derks, Sarah, Creemers, Aafke, Ebbing, Eva A., Hooijer, Gerrit K., Meijer, Sybren L., van Berge Henegouwen, Mark I., Medema, Jan Paul, van Laarhoven, Hanneke W. M., Bijlsma, Maarten F.
Published in Communications medicine (17.05.2024)
Published in Communications medicine (17.05.2024)
Get full text
Journal Article
Systemic effects of angiogenesis inhibition alter pharmacokinetics and intratumoral delivery of nab-paclitaxel
Steins, Anne, Ebbing, Eva A., Pistorius, Marcel C. M., Waasdorp, Cynthia, Krishnadath, Kausilia K., Medema, Jan Paul, Wilmink, Johanna W., Mathôt, Ron A. A., Bijlsma, Maarten F., van Laarhoven, Hanneke W. M.
Published in Drug delivery (2017)
Published in Drug delivery (2017)
Get full text
Journal Article
Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract
Damhofer, Helene, Ebbing, Eva A, Steins, Anne, Welling, Lieke, Tol, Johanna A, Krishnadath, Kausilia K, van Leusden, Tom, van de Vijver, Marc J, Besselink, Marc G, Busch, Olivier R, Henegouwen, Mark I van Berge, van Delden, Otto, Meijer, Sybren L, Dijk, Frederike, Medema, Jan Paul, van Laarhoven, Hanneke W, Bijlsma, Maarten F
Published in Journal of translational medicine (11.04.2015)
Published in Journal of translational medicine (11.04.2015)
Get full text
Journal Article
Esophageal Adenocarcinoma Cells and Xenograft Tumors Exposed to Erb-b2 Receptor Tyrosine Kinase 2 and 3 Inhibitors Activate Transforming Growth Factor Beta Signaling, Which Induces Epithelial to Mesenchymal Transition
Ebbing, Eva A, Steins, Anne, Fessler, Evelyn, Stathi, Phylicia, Lesterhuis, Willem Joost, Krishnadath, Kausilia K, Vermeulen, Louis, Medema, Jan Paul, Bijlsma, Maarten F, van Laarhoven, Hanneke W.M
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2017)
Published in Gastroenterology (New York, N.Y. 1943) (01.07.2017)
Get full text
Journal Article
Chemoradiation induces epithelial‐to‐mesenchymal transition in esophageal adenocarcinoma
Steins, Anne, Ebbing, Eva A., Creemers, Aafke, Zalm, Amber P., Jibodh, Rajni A., Waasdorp, Cynthia, Meijer, Sybren L., Delden, Otto M., Krishnadath, Kausilia K., Hulshof, Maarten C.C.M., Bennink, Roelof J., Punt, Cornelis J.A., Medema, Jan Paul, Bijlsma, Maarten F., Laarhoven, Hanneke W.M.
Published in International journal of cancer (15.11.2019)
Published in International journal of cancer (15.11.2019)
Get full text
Journal Article
ADAM10-mediated release of heregulin confers resistance to trastuzumab by activating HER3
Ebbing, Eva A, Medema, Jan Paul, Damhofer, Helene, Meijer, Sybren L, Krishnadath, Kausilia K, van Berge Henegouwen, Mark I, Bijlsma, Maarten F, van Laarhoven, Hanneke W M
Published in Oncotarget (01.03.2016)
Published in Oncotarget (01.03.2016)
Get full text
Journal Article
The dynamics of HER2 status in esophageal adenocarcinoma
Creemers, Aafke, Ebbing, Eva A, Hooijer, Gerrit K J, Stap, Lisanne, Jibodh-Mulder, Rajni A, Gisbertz, Susanne S, van Berge Henegouwen, Mark I, van Montfoort, Maurits L, Hulshof, Maarten C C M, Krishnadath, Kausilia K, van Oijen, Martijn G H, Bijlsma, Maarten F, Meijer, Sybren L, van Laarhoven, Hanneke W M
Published in Oncotarget (01.06.2018)
Published in Oncotarget (01.06.2018)
Get full text
Journal Article
Establishment of patient-derived xenograft models and cell lines for malignancies of the upper gastrointestinal tract
Damhofer, Helene, Ebbing, Eva A, Steins, Anne, Welling, Lieke, Tol, Johanna A, Krishnadath, Kausilia K, van Leusden, Tom, van de Vijver, Marc J, Besselink, Marc G, Busch, Olivier R, van Berge Henegouwen, Mark I, van Delden, Otto, Meijer, Sybren L, Dijk, Frederike, Medema, Jan Paul, van Laarhoven, Hanneke W, Bijlsma, Maarten F
Published in Journal of translational medicine (11.04.2015)
Published in Journal of translational medicine (11.04.2015)
Get full text
Journal Article
Abstract 350: HER3 mediates acquired resistance to HER2-targeted therapy in esophageal adenocarcinoma
Ebbing, Eva A., Medema, Jan Paul, Meijer, Sybren L., Krishnadath, Kausilia K., van Berge Henegouwen, Mark I., Bijlsma, Maarten F., van Laarhoven, Hanneke W. M.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Get full text
Journal Article