Expression-based drug screening of neural progenitor cells from individuals with schizophrenia
Readhead, Benjamin, Hartley, Brigham J, Eastwood, Brian J, Collier, David A, Evans, David, Farias, Richard, He, Ching, Hoffman, Gabriel, Sklar, Pamela, Dudley, Joel T, Schadt, Eric E, Savić, Radoslav, Brennand, Kristen J
Published in Nature communications (24.10.2018)
Published in Nature communications (24.10.2018)
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A human tau seeded neuronal cell model recapitulates molecular responses associated with Alzheimer's disease
Ficulle, Elena, Kananathan, Sarubini, Airey, David, Gharbi, Severine I, Humphryes-Kirilov, Neil, Scherschel, James, Dunbar, Charlotte, Eastwood, Brian J, Laing, Emma, Collier, David A, Bose, Suchira
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Published in Scientific reports (17.02.2022)
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A Bayesian gene network reveals insight into the JAK-STAT pathway in systemic lupus erythematosus
Li, Yupeng, Higgs, Richard E, Hoffman, Robert W, Dow, Ernst R, Liu, Xiong, Petri, Michelle, Wallace, Daniel J, Dörner, Thomas, Eastwood, Brian J, Miller, Bradley B, Liu, Yushi
Published in PloS one (02.12.2019)
Published in PloS one (02.12.2019)
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Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model
Wang, Hong, Li, Yupeng, Ryder, John W, Hole, Justin T, Ebert, Philip J, Airey, David C, Qian, Hui-Rong, Logsdon, Benjamin, Fisher, Alice, Ahmed, Zeshan, Murray, Tracey K, Cavallini, Annalisa, Bose, Suchira, Eastwood, Brian J, Collier, David A, Dage, Jeffrey L, Miller, Bradley B, Merchant, Kalpana M, O'Neill, Michael J, Demattos, Ronald B
Published in Molecular neurodegeneration (17.12.2018)
Published in Molecular neurodegeneration (17.12.2018)
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Mechanism of action deconvolution of the small-molecule pathological tau aggregation inhibitor Anle138b
Hosseini-Gerami, Layla, Ficulle, Elena, Humphryes-Kirilov, Neil, Airey, David C, Scherschel, James, Kananathan, Sarubini, Eastwood, Brian J, Bose, Suchira, Collier, David A, Laing, Emma, Evans, David, Broughton, Howard, Bender, Andreas
Published in Alzheimer's research & therapy (14.03.2023)
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Myostatin Neutralization Results in Preservation of Muscle Mass and Strength in Preclinical Models of Tumor-Induced Muscle Wasting
Smith, Rosamund C, Cramer, Martin S, Mitchell, Pamela J, Capen, Andrew, Huber, Lysiane, Wang, Rong, Myers, Laura, Jones, Bryan E, Eastwood, Brian J, Ballard, Darryl, Hanson, Jeff, Credille, Kelly M, Wroblewski, Victor J, Lin, Boris K, Heuer, Josef G
Published in Molecular cancer therapeutics (01.07.2015)
Published in Molecular cancer therapeutics (01.07.2015)
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Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia
Readhead, Benjamin, Hartley, Brigham J, Eastwood, Brian J, Collier, David A, Evans, David, Farias, Richard, He, Ching, Hoffman, Gabriel, Sklar, Pamela, Dudley, Joel T, Schadt, Eric E, Savić, Radoslav, Brennand, Kristen J
Published in Nature communications (19.11.2018)
Published in Nature communications (19.11.2018)
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Quantitative propagation of assembled human Tau from Alzheimer's disease brain in microfluidic neuronal cultures
Katsikoudi, Antigoni, Ficulle, Elena, Cavallini, Annalisa, Sharman, Gary, Guyot, Amelie, Zagnoni, Michele, Eastwood, Brian J., Hutton, Michael, Bose, Suchira
Published in The Journal of biological chemistry (11.09.2020)
Published in The Journal of biological chemistry (11.09.2020)
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The minimum significant ratio: a statistical parameter to characterize the reproducibility of potency estimates from concentration-response assays and estimation by replicate-experiment studies
Eastwood, Brian J, Farmen, Mark W, Iversen, Philip W, Craft, Trelia J, Smallwood, Jeffrey K, Garbison, Kim E, Delapp, Neil W, Smith, Gerald F
Published in Journal of biomolecular screening (01.04.2006)
Published in Journal of biomolecular screening (01.04.2006)
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Analgesic effects of serotonergic, noradrenergic or dual reuptake inhibitors in the carrageenan test in rats: Evidence for synergism between serotonergic and noradrenergic reuptake inhibition
Jones, Carrie K., Eastwood, Brian J., Need, Anne B., Shannon, Harlan E.
Published in Neuropharmacology (01.12.2006)
Published in Neuropharmacology (01.12.2006)
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The Dopamine D1 Receptor Positive Allosteric Modulator Mevidalen (LY3154207) Enhances Wakefulness in the Humanized D1 Mouse and in Sleep-Deprived Healthy Male Volunteers
McCarthy, Andrew P, Svensson, Kjell A, Shanks, Elaine, Brittain, Claire, Eastwood, Brian J, Kielbasa, William, Biglan, Kevin M, Wafford, Keith A
Published in The Journal of pharmacology and experimental therapeutics (01.03.2022)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2022)
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Preclinical profile of a dopamine D1 potentiator suggests therapeutic utility in neurological and psychiatric disorders
Bruns, Robert F., Mitchell, Stephen N., Wafford, Keith A., Harper, Alex J., Shanks, Elaine A., Carter, Guy, O'Neill, Michael J., Murray, Tracey K., Eastwood, Brian J., Schaus, John M., Beck, James P., Hao, Junliang, Witkin, Jeffrey M., Li, Xia, Chernet, Eyassu, Katner, Jason S., Wang, Hong, Ryder, John W., Masquelin, Meghane E., Thompson, Linda K., Love, Patrick L., Maren, Deanna L., Falcone, Julie F., Menezes, Michelle M., Zhang, Linli, Yang, Charles R., Svensson, Kjell A.
Published in Neuropharmacology (01.01.2018)
Published in Neuropharmacology (01.01.2018)
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Electroencephalographic, cognitive, and neurochemical effects of LY3130481 (CERC-611), a selective antagonist of TARP-γ8-associated AMPA receptors
Witkin, Jeffrey M., Li, Jennifer, Gilmour, Gary, Mitchell, Stephen N., Carter, Guy, Gleason, Scott D., Seidel, Wesley F., Eastwood, Brian J., McCarthy, Andrew, Porter, Warren J., Reel, Jon, Gardinier, Kevin M., Kato, Akihiko S., Wafford, Keith A.
Published in Neuropharmacology (01.11.2017)
Published in Neuropharmacology (01.11.2017)
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Activation of mesolimbic dopamine neurons during novel and daily limited access to palatable food is blocked by the opioid antagonist LY255582
Sahr, Allison E, Sindelar, Dana K, Alexander-Chacko, Jesline T, Eastwood, Brian J, Mitch, Charles H, Statnick, Michael A
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.08.2008)
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.08.2008)
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Dopamine D1/5 Receptor Modulation of Firing Rate and Bidirectional Theta Burst Firing in Medial Septal/Vertical Limb of Diagonal Band Neurons In Vivo
Fitch, Thomas E, Sahr, Robert N, Eastwood, Brian J, Zhou, Feng C, Yang, Charles R
Published in Journal of neurophysiology (01.05.2006)
Published in Journal of neurophysiology (01.05.2006)
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A randomized, placebo-controlled trial of erythromycin estolate chemoprophylaxis for household contacts of children with culture-positive bordetella pertussis infection
Halperin, S A, Bortolussi, R, Langley, J M, Eastwood, B J, De Serres, G
Published in Pediatrics (Evanston) (01.10.1999)
Published in Pediatrics (Evanston) (01.10.1999)
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