CAR T Cells Targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors
Majzner, Robbie G, Theruvath, Johanna L, Nellan, Anandani, Heitzeneder, Sabine, Cui, Yongzhi, Mount, Christopher W, Rietberg, Skyler P, Linde, Miles H, Xu, Peng, Rota, Christopher, Sotillo, Elena, Labanieh, Louai, Lee, Daniel W, Orentas, Rimas J, Dimitrov, Dimiter S, Zhu, Zhongyu, Croix, Brad St, Delaidelli, Alberto, Sekunova, Alla, Bonvini, Ezio, Mitra, Siddhartha S, Quezado, Martha M, Majeti, Ravindra, Monje, Michelle, Sorensen, Poul H B, Maris, John M, Mackall, Crystal L
Published in Clinical cancer research (15.04.2019)
Published in Clinical cancer research (15.04.2019)
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Teplizumab Preserves C-Peptide in Recent-Onset Type 1 Diabetes
Hagopian, William, Ferry, Robert J., Sherry, Nicole, Carlin, David, Bonvini, Ezio, Johnson, Syd, Stein, Kathryn E., Koenig, Scott, Daifotis, Anastasia G., Herold, Kevan C., Ludvigsson, Johnny
Published in Diabetes (New York, N.Y.) (01.11.2013)
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A CD3xCD123 bispecific DART for redirecting host T cells to myelogenous leukemia: preclinical activity and safety in nonhuman primates
Chichili, Gurunadh R, Huang, Ling, Li, Hua, Burke, Steve, He, Leilei, Tang, Qin, Jin, Linda, Gorlatov, Sergey, Ciccarone, Valentina, Chen, Francine, Koenig, Scott, Shannon, Michele, Alderson, Ralph, Moore, Paul A, Johnson, Syd, Bonvini, Ezio
Published in Science translational medicine (27.05.2015)
Published in Science translational medicine (27.05.2015)
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Targeting CD123 in acute myeloid leukemia using a T-cell–directed dual-affinity retargeting platform
Al-Hussaini, Muneera, Rettig, Michael P., Ritchey, Julie K., Karpova, Darja, Uy, Geoffrey L., Eissenberg, Linda G., Gao, Feng, Eades, William C., Bonvini, Ezio, Chichili, Gurunadh R., Moore, Paul A., Johnson, Syd, Collins, Lynne, DiPersio, John F.
Published in Blood (07.01.2016)
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Efficacy of Margetuximab vs Trastuzumab in Patients With Pretreated ERBB2-Positive Advanced Breast Cancer: A Phase 3 Randomized Clinical Trial
Rugo, Hope S, Im, Seock-Ah, Cardoso, Fatima, Cortés, Javier, Curigliano, Giuseppe, Musolino, Antonino, Pegram, Mark D, Wright, Gail S, Saura, Cristina, Escrivá-de-Romaní, Santiago, De Laurentiis, Michelino, Levy, Christelle, Brown-Glaberman, Ursa, Ferrero, Jean-Marc, de Boer, Maaike, Kim, Sung-Bae, Petráková, Katarína, Yardley, Denise A, Freedman, Orit, Jakobsen, Erik H, Kaufman, Bella, Yerushalmi, Rinat, Fasching, Peter A, Nordstrom, Jeffrey L, Bonvini, Ezio, Koenig, Scott, Edlich, Sutton, Hong, Shengyan, Rock, Edwin P, Gradishar, William J
Published in JAMA oncology (01.04.2021)
Published in JAMA oncology (01.04.2021)
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Combinatorial Anti-Tumor Activity in Animal Models of a Novel CD123 x CD3 Bispecific Dart® Molecule (MGD024) with Cytarabine, Venetoclax or Azacitidine Supports Combination Therapy in Acute Myeloid Leukemia
Alderson, Ralph F., Huang, Ling, Zhang, Xiaoyu, Li, Haiquan, Kaufman, Thomas, Diedrich, Gundo, Moore, Paul, Bonvini, Ezio
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Functional Independence and Interdependence of the Src Homology Domains of Phospholipase C-γ1 in B-Cell Receptor Signal Transduction
DeBell, Karen E., Stoica, Bogdan A., Verí, Maria-Concetta, Di Baldassarre, Angela, Miscia, Sebastiano, Graham, Laurie J., Rellahan, Barbara L., Ishiai, Masamichi, Kurosaki, Tomohiro, Bonvini, Ezio
Published in Molecular and Cellular Biology (01.11.1999)
Published in Molecular and Cellular Biology (01.11.1999)
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70Z/3 Cbl induces PLCγ1 activation in T lymphocytes via an alternate Lat- and Slp-76-independent signaling mechanism
GRAHAM, Laurie J, VERI, Maria-Concetta, DEBELL, Karen E, NOVIELLO, Cristiana, RAWAT, Rashmi, JEN, Sandy, BONVINI, Ezio, RELLAHAN, Barbara
Published in Oncogene (24.04.2003)
Published in Oncogene (24.04.2003)
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Teplizumab Preserves C-Peptide in Recent-Onset Type 1 Diabetes: Two-Year Results From the Randomized, Placebo-Controlled Protégé Trial
HAGOPIAN, William, FERRY, Robert J, LUDVIGSSON, Johnny, SHERRY, Nicole, CARLIN, David, BONVINI, Ezio, JOHNSON, Syd, STEIN, Kathryn E, KOENIG, Scott, DAIFOTIS, Anastasia G, HEROLD, Kevan C
Published in Diabetes (New York, N.Y.) (01.11.2013)
Published in Diabetes (New York, N.Y.) (01.11.2013)
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Abstract 1555: Enhanced HER2-dependent immune activation by margetuximab, an investigational Fc-engineered anti-HER2 mAb, supports combination with checkpoint blockade
Zhang, Xiaoyu, Li, Haiquan, Yang, Yinhua, Xu, Qihong, Kaufman, Tom, Smith, Doug, Nordstrom, Jeffrey, Bonvini, Ezio, Moore, Paul
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Modeling Flotetuzumab-Associated CRS in AML Using inVitro and inVivo Preclinical Models
Patel, Dilan Anil, Chendamarai, Ezhilarasi, Ritchey, Julie K., Rettig, Michael P., Gehrs, Leah, Moore, Paul, Alderson, Ralph F., Bonvini, Ezio, Christopher, Matthew, DiPersio, John F.
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Modeling Flotetuzumab-Associated CRS in AML Using in Vitro and in Vivo Preclinical Models
Patel, Dilan Anil, Chendamarai, Ezhilarasi, Ritchey, Julie K., Rettig, Michael P., Gehrs, Leah, Moore, Paul, Alderson, Ralph F., Bonvini, Ezio, Christopher, Matthew, DiPersio, John F.
Published in Blood (15.11.2022)
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Flotetuzumab and other T-cell immunotherapies upregulate MHC class II expression on acute myeloid leukemia cells
Rimando, Joseph C., Chendamarai, Ezhilarasi, Rettig, Michael P., Jayasinghe, Reyka, Christopher, Matthew J., Ritchey, Julie K., Christ, Stephanie, Kim, Miriam Y., Bonvini, Ezio, DiPersio, John F.
Published in Blood (06.04.2023)
Published in Blood (06.04.2023)
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Application of dual affinity retargeting molecules to achieve optimal redirected T-cell killing of B-cell lymphoma
Moore, Paul A., Zhang, Wenjun, Rainey, G. Jonah, Burke, Steve, Li, Hua, Huang, Ling, Gorlatov, Sergey, Veri, Maria Concetta, Aggarwal, Sudeepta, Yang, Yinhua, Shah, Kalpana, Jin, Linda, Zhang, Sunan, He, Leilei, Zhang, Tengfei, Ciccarone, Valentina, Koenig, Scott, Bonvini, Ezio, Johnson, Syd
Published in Blood (28.04.2011)
Published in Blood (28.04.2011)
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AML-080 Modeling Flotetuzumab-Associated Cytokine Release Syndrome (CRS) in AML Using In Vitro and In Vivo Preclinical Models
Patel, Dilan, Chendamarai, Ezhil, Ritchey, Julie, Rettig, Michael, Gehrs, Leah, Moore, Paul, Alderson, Ralph, Bonvini, Ezio, Christopher, Matthew, DiPersio, John
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
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POSTER: AML-080 Modeling Flotetuzumab-Associated Cytokine Release Syndrome (CRS) in AML Using In Vitro and In Vivo Preclinical Models
Patel, Dilan, Chendamarai, Ezhil, Ritchey, Julie, Rettig, Michael, Gehrs, Leah, Moore, Paul, Alderson, Ralph, Bonvini, Ezio, Christopher, Matthew, DiPersio, John
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2023)
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Abstract 950: Targeting B7-H3 in squamous cell carcinoma of the head and neck: Preclinical proof-of-concept with the investigational anti-B7-H3 antibody-drug conjugate, MGC018
Scribner, Juniper A., Chen, Francine Z., Li, Ying, Chiechi, Michael, Son, Thomas, Hooley, Jeff, Koenig, Scott, Moore, Paul A., Bonvini, Ezio, Bohac, Chet, Loo, Deryk
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Effector Cell Recruitment with Novel Fv-based Dual-affinity Re-targeting Protein Leads to Potent Tumor Cytolysis and in Vivo B-cell Depletion
Johnson, Syd, Burke, Stephen, Huang, Ling, Gorlatov, Sergey, Li, Hua, Wang, Weili, Zhang, Wenjun, Tuaillon, Nadine, Rainey, Jonah, Barat, Bhaswati, Yang, Yinhua, Jin, Linda, Ciccarone, Valentina, Moore, Paul A., Koenig, Scott, Bonvini, Ezio
Published in Journal of molecular biology (11.06.2010)
Published in Journal of molecular biology (11.06.2010)
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Development of an Fc-Enhanced Anti―B7-H3 Monoclonal Antibody with Potent Antitumor Activity
LOO, Deryk, ALDERSON, Ralph F, SON, Tom, YAN CHEN, EASTON, Ann N, LI, Jonathan C, RILLEMA, Jill R, LICEA, Monica, FIEGER, Claudia, LIANG, Tony W, MATHER, Jennie P, KOENIG, Scott, CHEN, Francine Z, STEWART, Stanford J, JOHNSON, Syd, BONVINI, Ezio, MOORE, Paul A, LING HUANG, WENJUN ZHANG, GORLATOV, Sergey, BURKE, Steve, CICCARONE, Valentina, HUA LI, YINHUA YANG
Published in Clinical cancer research (15.07.2012)
Published in Clinical cancer research (15.07.2012)
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