Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease
Eyers, Patrick A, Keeshan, Karen, Kannan, Natarajan
Published in Trends in cell biology (01.04.2017)
Published in Trends in cell biology (01.04.2017)
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Journal Article
Day of the dead: pseudokinases and pseudophosphatases in physiology and disease
Reiterer, Veronika, Eyers, Patrick A, Farhan, Hesso
Published in Trends in cell biology (01.09.2014)
Published in Trends in cell biology (01.09.2014)
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Journal Article
Strong anion exchange‐mediated phosphoproteomics reveals extensive human non‐canonical phosphorylation
Hardman, Gemma, Perkins, Simon, Brownridge, Philip J, Clarke, Christopher J, Byrne, Dominic P, Campbell, Amy E, Kalyuzhnyy, Anton, Myall, Ashleigh, Eyers, Patrick A, Jones, Andrew R, Eyers, Claire E
Published in The EMBO journal (04.10.2019)
Published in The EMBO journal (04.10.2019)
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Journal Article
Bio-Zombie: the rise of pseudoenzymes in biology
Murphy, James M, Farhan, Hesso, Eyers, Patrick A
Published in Biochemical Society transactions (15.04.2017)
Published in Biochemical Society transactions (15.04.2017)
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Journal Article
Local protein kinase A action proceeds through intact holoenzymes
Smith, F. Donelson, Esseltine, Jessica L., Nygren, Patrick J., Veesler, David, Byrne, Dominic P., Vonderach, Matthias, Strashnov, Ilya, Eyers, Claire E., Eyers, Patrick A., Langeberg, Lorene K., Scott, John D.
Published in Science (American Association for the Advancement of Science) (23.06.2017)
Published in Science (American Association for the Advancement of Science) (23.06.2017)
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Journal Article
Tracing the origin and evolution of pseudokinases across the tree of life
Kwon, Annie, Scott, Steven, Taujale, Rahil, Yeung, Wayland, Kochut, Krys J, Eyers, Patrick A, Kannan, Natarajan
Published in Science signaling (23.04.2019)
Published in Science signaling (23.04.2019)
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Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential
Meyer, Bjoern, Chiaravalli, Jeanne, Gellenoncourt, Stacy, Brownridge, Philip, Bryne, Dominic P., Daly, Leonard A., Grauslys, Arturas, Walter, Marius, Agou, Fabrice, Chakrabarti, Lisa A., Craik, Charles S., Eyers, Claire E., Eyers, Patrick A., Gambin, Yann, Jones, Andrew R., Sierecki, Emma, Verdin, Eric, Vignuzzi, Marco, Emmott, Edward
Published in Nature communications (21.09.2021)
Published in Nature communications (21.09.2021)
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Journal Article
New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome
Wilson, Leah J, Linley, Adam, Hammond, Dean E, Hood, Fiona E, Coulson, Judy M, MacEwan, David J, Ross, Sarah J, Slupsky, Joseph R, Smith, Paul D, Eyers, Patrick A, Prior, Ian A
Published in Cancer research (Chicago, Ill.) (01.01.2018)
Published in Cancer research (Chicago, Ill.) (01.01.2018)
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Journal Article
BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-XL
Greaves, Georgia, Milani, Mateus, Butterworth, Michael, Carter, Rachel J., Byrne, Dominic P., Eyers, Patrick A., Luo, Xu, Cohen, Gerald M., Varadarajan, Shankar
Published in Cell death and differentiation (01.06.2019)
Published in Cell death and differentiation (01.06.2019)
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Journal Article
Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity
Byrne, Dominic P, Shrestha, Safal, Galler, Martin, Cao, Min, Daly, Leonard A, Campbell, Amy E, Eyers, Claire E, Veal, Elizabeth A, Kannan, Natarajan, Eyers, Patrick A
Published in Science signaling (07.07.2020)
Published in Science signaling (07.07.2020)
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Journal Article
Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes
Bury, Leah, Coelho, Paula A, Simeone, Angela, Ferries, Samantha, Eyers, Claire E, Eyers, Patrick A, Zernicka-Goetz, Magdalena, Glover, David M
Published in The Journal of cell biology (06.11.2017)
Published in The Journal of cell biology (06.11.2017)
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Journal Article
Randomized clinical trial of laparoscopic versus open abdominal rectopexy for rectal prolapse
Solomon, M. J., Young, C. J., Eyers, A. A., Roberts, R. A.
Published in British journal of surgery (01.01.2002)
Published in British journal of surgery (01.01.2002)
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Journal Article
Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells
Foulkes, Daniel M, Byrne, Dominic P, Yeung, Wayland, Shrestha, Safal, Bailey, Fiona P, Ferries, Samantha, Eyers, Claire E, Keeshan, Karen, Wells, Carrow, Drewry, David H, Zuercher, William J, Kannan, Natarajan, Eyers, Patrick A
Published in Science signaling (25.09.2018)
Published in Science signaling (25.09.2018)
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Journal Article
A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties
Murphy, James M, Zhang, Qingwei, Young, Samuel N, Reese, Michael L, Bailey, Fiona P, Eyers, Patrick A, Ungureanu, Daniela, Hammaren, Henrik, Silvennoinen, Olli, Varghese, Leila N, Chen, Kelan, Tripaydonis, Anne, Jura, Natalia, Fukuda, Koichi, Qin, Jun, Nimchuk, Zachary, Mudgett, Mary Beth, Elowe, Sabine, Gee, Christine L, Liu, Ling, Daly, Roger J, Manning, Gerard, Babon, Jeffrey J, Lucet, Isabelle S
Published in Biochemical journal (15.01.2014)
Published in Biochemical journal (15.01.2014)
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Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota
Luis, Ana S, Baslé, Arnaud, Byrne, Dominic P., Wright, Gareth S. A., London, James A., Jin, Chunsheng, Karlsson, Niclas G., Hansson, Gunnar C., Eyers, Patrick A., Czjzek, Mirjam, Barbeyron, Tristan, Yates, Edwin A., Martens, Eric C., Cartmell, Alan
Published in Nature chemical biology (01.08.2022)
Published in Nature chemical biology (01.08.2022)
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Journal Article
KinOrtho: a method for mapping human kinase orthologs across the tree of life and illuminating understudied kinases
Huang, Liang-Chin, Taujale, Rahil, Gravel, Nathan, Venkat, Aarya, Yeung, Wayland, Byrne, Dominic P, Eyers, Patrick A, Kannan, Natarajan
Published in BMC bioinformatics (18.09.2021)
Published in BMC bioinformatics (18.09.2021)
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Journal Article
A framework for identification of actionable cancer genome dependencies in small cell lung cancer
Sos, Martin L., Dietlein, Felix, Peifer, Martin, Schöttle, Jakob, Balke-Want, Hyatt, Müller, Christian, Koker, Mirjam, Richters, André, Heynck, Stefanie, Malchers, Florian, Heuckmann, Johannes M., Seidel, Danila, Eyers, Patrick A., Ullrich, Rolad T., Antonchick, Andrey P., Vintonyak, Viktor V., Schneider, Peter M., Ninomiya, Takashi, Waldmann, Herbert, Büttner, Reinhard, Rauh, Daniel, Heukamp, Lukas C., Thomas, Roman K.
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2012)
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Journal Article
The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner
Bailey, Fiona P, Byrne, Dominic P, Oruganty, Krishnadev, Eyers, Claire E, Novotny, Christopher J, Shokat, Kevan M, Kannan, Natarajan, Eyers, Patrick A
Published in Biochemical journal (01.04.2015)
Published in Biochemical journal (01.04.2015)
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