A review of Phase I trials of Ebola virus vaccines: what can we learn from the race to develop novel vaccines?
Lambe, Teresa, Bowyer, Georgina, Ewer, Katie J
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (26.05.2017)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (26.05.2017)
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Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial
Datoo, Mehreen S, Natama, Magloire H, Somé, Athanase, Traoré, Ousmane, Rouamba, Toussaint, Bellamy, Duncan, Yameogo, Prisca, Valia, Daniel, Tegneri, Moubarak, Ouedraogo, Florence, Soma, Rachidatou, Sawadogo, Seydou, Sorgho, Faizatou, Derra, Karim, Rouamba, Eli, Orindi, Benedict, Ramos Lopez, Fernando, Flaxman, Amy, Cappuccini, Federica, Kailath, Reshma, Elias, Sean, Mukhopadhyay, Ekta, Noe, Andres, Cairns, Matthew, Lawrie, Alison, Roberts, Rachel, Valéa, Innocent, Sorgho, Hermann, Williams, Nicola, Glenn, Gregory, Fries, Louis, Reimer, Jenny, Ewer, Katie J, Shaligram, Umesh, Hill, Adrian V S, Tinto, Halidou
Published in The Lancet (British edition) (15.05.2021)
Published in The Lancet (British edition) (15.05.2021)
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Viral vectors as vaccine platforms: from immunogenicity to impact
Ewer, Katie J, Lambe, Teresa, Rollier, Christine S, Spencer, Alexandra J, Hill, Adrian VS, Dorrell, Lucy
Published in Current opinion in immunology (01.08.2016)
Published in Current opinion in immunology (01.08.2016)
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Efficacy and immunogenicity of R21/Matrix-M vaccine against clinical malaria after 2 years' follow-up in children in Burkina Faso: a phase 1/2b randomised controlled trial
Datoo, Mehreen S, Natama, Hamtandi Magloire, Somé, Athanase, Bellamy, Duncan, Traoré, Ousmane, Rouamba, Toussaint, Tahita, Marc Christian, Ido, N Félix André, Yameogo, Prisca, Valia, Daniel, Millogo, Aida, Ouedraogo, Florence, Soma, Rachidatou, Sawadogo, Seydou, Sorgho, Faizatou, Derra, Karim, Rouamba, Eli, Ramos-Lopez, Fernando, Cairns, Matthew, Provstgaard-Morys, Samuel, Aboagye, Jeremy, Lawrie, Alison, Roberts, Rachel, Valéa, Innocent, Sorgho, Hermann, Williams, Nicola, Glenn, Gregory, Fries, Louis, Reimer, Jenny, Ewer, Katie J, Shaligram, Umesh, Hill, Adrian V S, Tinto, Halidou
Published in The Lancet infectious diseases (01.12.2022)
Published in The Lancet infectious diseases (01.12.2022)
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First field efficacy trial of the ChAd63 MVA ME-TRAP vectored malaria vaccine candidate in 5-17 months old infants and children
Tiono, Alfred B, Nébié, Issa, Anagnostou, Nicholas, Coulibaly, Aboubacar S, Bowyer, Georgina, Lam, Erika, Bougouma, Edith C, Ouedraogo, Alphonse, Yaro, Jean Baptist B, Barry, Aïssata, Roberts, Rachel, Rampling, Tommy, Bliss, Carly, Hodgson, Susanne, Lawrie, Alison, Ouedraogo, Amidou, Imoukhuede, Egeruan Babatunde, Ewer, Katie J, Viebig, Nicola K, Diarra, Amidou, Leroy, Odile, Bejon, Philip, Hill, Adrian V S, Sirima, Sodiomon B
Published in PloS one (12.12.2018)
Published in PloS one (12.12.2018)
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Safety, Immunogenicity and Efficacy of Prime-Boost Vaccination with ChAd63 and MVA Encoding ME-TRAP against Plasmodium falciparum Infection in Adults in Senegal
Mensah, Victorine A, Gueye, Aly, Ndiaye, Magatte, Edwards, Nick J, Wright, Danny, Anagnostou, Nicholas A, Syll, Massamba, Ndaw, Amy, Abiola, Annie, Bliss, Carly, Gomis, Jules-François, Petersen, Ines, Ogwang, Caroline, Dieye, Tandakha, Viebig, Nicola K, Lawrie, Alison M, Roberts, Rachel, Nicosia, Alfredo, Faye, Babacar, Gaye, Oumar, Leroy, Odile, Imoukhuede, Egeruan B, Ewer, Katie J, Bejon, Philip, Hill, Adrian V S, Cisse, Badara
Published in PloS one (15.12.2016)
Published in PloS one (15.12.2016)
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Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in HIV infection: a single-arm substudy of a phase 2/3 clinical trial
Frater, John, Ewer, Katie J, Ogbe, Ane, Pace, Mathew, Adele, Sandra, Adland, Emily, Alagaratnam, Jasmini, Aley, Parvinder K, Ali, Mohammad, Ansari, M Azim, Bara, Anna, Bittaye, Mustapha, Broadhead, Samantha, Brown, Anthony, Brown, Helen, Cappuccini, Federica, Cooney, Enya, Dejnirattisai, Wanwisa, Dold, Christina, Fairhead, Cassandra, Fok, Henry, Folegatti, Pedro M, Fowler, Jamie, Gibbs, Charlotte, Goodman, Anna L, Jenkin, Daniel, Jones, Mathew, Makinson, Rebecca, Marchevsky, Natalie G, Mujadidi, Yama F, Nguyen, Hanna, Parolini, Lucia, Petersen, Claire, Plested, Emma, Pollock, Katrina M, Ramasamy, Maheshi N, Rhead, Sarah, Robinson, Hannah, Robinson, Nicola, Rongkard, Patpong, Ryan, Fiona, Serrano, Sonia, Tipoe, Timothy, Voysey, Merryn, Waters, Anele, Zacharopoulou, Panagiota, Barnes, Eleanor, Dunachie, Susanna, Goulder, Philip, Klenerman, Paul, Screaton, Gavin R, Winston, Alan, Hill, Adrian V S, Gilbert, Sarah C, Pollard, Andrew J, Fidler, Sarah, Fox, Julie, Lambe, Teresa
Published in The lancet HIV (01.08.2021)
Published in The lancet HIV (01.08.2021)
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A single dose of ChAdOx1 Chik vaccine induces neutralizing antibodies against four chikungunya virus lineages in a phase 1 clinical trial
Folegatti, Pedro M., Harrison, Kate, Preciado-Llanes, Lorena, Lopez, Fernando Ramos, Bittaye, Mustapha, Kim, Young Chan, Flaxman, Amy, Bellamy, Duncan, Makinson, Rebecca, Sheridan, Jonathan, Azar, Sasha R., Campos, Rafael Kroon, Tilley, Mark, Tran, Nguyen, Jenkin, Daniel, Poulton, Ian, Lawrie, Alison, Roberts, Rachel, Berrie, Eleanor, Rossi, Shannan L., Hill, Adrian, Ewer, Katie J., Reyes-Sandoval, Arturo
Published in Nature communications (30.07.2021)
Published in Nature communications (30.07.2021)
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Tolerability and immunogenicity of an intranasally-administered adenovirus-vectored COVID-19 vaccine: An open-label partially-randomised ascending dose phase I trial
Madhavan, Meera, Ritchie, Adam J., Aboagye, Jeremy, Jenkin, Daniel, Provstgaad-Morys, Samuel, Tarbet, Iona, Woods, Danielle, Davies, Sophie, Baker, Megan, Platt, Abigail, Flaxman, Amy, Smith, Holly, Belij-Rammerstorfer, Sandra, Wilkins, Deidre, Kelly, Elizabeth J., Villafana, Tonya, Green, Justin A., Poulton, Ian, Lambe, Teresa, Hill, Adrian V.S., Ewer, Katie J., Douglas, Alexander D.
Published in EBioMedicine (01.11.2022)
Published in EBioMedicine (01.11.2022)
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Prime and target immunization protects against liver-stage malaria in mice
Gola, Anita, Silman, Daniel, Walters, Adam A, Sridhar, Saranya, Uderhardt, Stefan, Salman, Ahmed M, Halbroth, Benedict R, Bellamy, Duncan, Bowyer, Georgina, Powlson, Jonathan, Baker, Megan, Venkatraman, Navin, Poulton, Ian, Berrie, Eleanor, Roberts, Rachel, Lawrie, Alison M, Angus, Brian, Khan, Shahid M, Janse, Chris J, Ewer, Katie J, Germain, Ronald N, Spencer, Alexandra J, Hill, Adrian V S
Published in Science translational medicine (26.09.2018)
Published in Science translational medicine (26.09.2018)
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A phase Ia study to assess the safety and immunogenicity of new malaria vaccine candidates ChAd63 CS administered alone and with MVA CS
de Barra, Eoghan, Hodgson, Susanne H, Ewer, Katie J, Bliss, Carly M, Hennigan, Kerrie, Collins, Ann, Berrie, Eleanor, Lawrie, Alison M, Gilbert, Sarah C, Nicosia, Alfredo, McConkey, Samuel J, Hill, Adrian V S
Published in PloS one (18.12.2014)
Published in PloS one (18.12.2014)
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Clinical Assessment of a Recombinant Simian Adenovirus ChAd63: A Potent New Vaccine Vector
O'Hara, Geraldine A., Duncan, Christopher J. A., Ewer, Katie J., Collins, Katharine A., Elias, Sean C., Halstead, Fenella D., Goodman, Anna L., Edwards, Nick J., Reyes-Sandoval, Arturo, Bird, Prudence, Rowland, Rosalind, Sheehy, Susanne H., Poulton, Ian D., Hutchings, Claire, Todryk, Stephen, Andrews, Laura, Folgori, Antonella, Berrie, Eleanor, Moyle, Sarah, Nicosia, Alfredo, Colloca, Stefano, Cortese, Riccardo, Siani, Loredana, Lawrie, Alison M., Gilbert, Sarah C., Hill, Adrian V. S.
Published in The Journal of infectious diseases (01.03.2012)
Published in The Journal of infectious diseases (01.03.2012)
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Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species
Colloca, Stefano, Barnes, Eleanor, Folgori, Antonella, Ammendola, Virginia, Capone, Stefania, Cirillo, Agostino, Siani, Loredana, Naddeo, Mariarosaria, Grazioli, Fabiana, Esposito, Maria Luisa, Ambrosio, Maria, Sparacino, Angela, Bartiromo, Marta, Meola, Annalisa, Smith, Kira, Kurioka, Ayako, O'Hara, Geraldine A, Ewer, Katie J, Anagnostou, Nicholas, Bliss, Carly, Hill, Adrian V S, Traboni, Cinzia, Klenerman, Paul, Cortese, Riccardo, Nicosia, Alfredo
Published in Science translational medicine (04.01.2012)
Published in Science translational medicine (04.01.2012)
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Reduced Ebola vaccine responses in CMV+ young adults is associated with expansion of CD57+KLRG1+ T cells
Bowyer, Georgina, Sharpe, Hannah, Venkatraman, Navin, Ndiaye, Pierre Birahim, Wade, Djibril, Brenner, Nicole, Mentzer, Alex, Mair, Catherine, Waterboer, Tim, Lambe, Teresa, Dieye, Tandakha, Mboup, Souleymane, Hill, Adrian V S, Ewer, Katie J
Published in The Journal of experimental medicine (06.07.2020)
Published in The Journal of experimental medicine (06.07.2020)
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Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation
Ewer, Katie J., O’Hara, Geraldine A., Duncan, Christopher J. A., Collins, Katharine A., Sheehy, Susanne H., Reyes-Sandoval, Arturo, Goodman, Anna L., Edwards, Nick J., Elias, Sean C., Halstead, Fenella D., Longley, Rhea J., Rowland, Rosalind, Poulton, Ian D., Draper, Simon J., Blagborough, Andrew M., Berrie, Eleanor, Moyle, Sarah, Williams, Nicola, Siani, Loredana, Folgori, Antonella, Colloca, Stefano, Sinden, Robert E., Lawrie, Alison M., Cortese, Riccardo, Gilbert, Sarah C., Nicosia, Alfredo, Hill, Adrian V. S.
Published in Nature communications (28.11.2013)
Published in Nature communications (28.11.2013)
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Evaluation of the Efficacy of ChAd63-MVA Vectored Vaccines Expressing Circumsporozoite Protein and ME-TRAP Against Controlled Human Malaria Infection in Malaria-Naive Individuals
Hodgson, Susanne H., Ewer, Katie J., Bliss, Carly M., Edwards, Nick J., Rampling, Thomas, Anagnostou, Nicholas A., de Barra, Eoghan, Havelock, Tom, Bowyer, Georgina, Poulton, Ian D., de Cassan, Simone, Longley, Rhea, Illingworth, Joseph J., Douglas, Alexander D., Mange, Pooja B., Collins, Katharine A., Roberts, Rachel, Gerry, Stephen, Berrie, Eleanor, Moyle, Sarah, Colloca, Stefano, Cortese, Riccardo, Sinden, Robert E., Gilbert, Sarah C., Bejon, Philip, Lawrie, Alison M., Nicosia, Alfredo, Faust, Saul N., Hill, Adrian V. S.
Published in The Journal of infectious diseases (01.04.2015)
Published in The Journal of infectious diseases (01.04.2015)
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Assessment of humoral immune responses to blood-stage malaria antigens following ChAd63-MVA immunization, controlled human malaria infection and natural exposure
Biswas, Sumi, Choudhary, Prateek, Elias, Sean C, Miura, Kazutoyo, Milne, Kathryn H, de Cassan, Simone C, Collins, Katharine A, Halstead, Fenella D, Bliss, Carly M, Ewer, Katie J, Osier, Faith H, Hodgson, Susanne H, Duncan, Christopher J A, O'Hara, Geraldine A, Long, Carole A, Hill, Adrian V S, Draper, Simon J
Published in PloS one (25.09.2014)
Published in PloS one (25.09.2014)
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